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Protein
Submitted name:

T-box containing protein

Gene

tbx16

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

  • DNA binding Source: ZFIN
  • DNA binding transcription factor activity Source: InterPro
  • transcription regulatory region DNA binding Source: ZFIN

GO - Biological processi

  • angiogenesis Source: ZFIN
  • convergent extension involved in axis elongation Source: ZFIN
  • convergent extension involved in nephron morphogenesis Source: ZFIN
  • determination of left/right symmetry Source: ZFIN
  • digestive tract development Source: ZFIN
  • embryonic heart tube morphogenesis Source: ZFIN
  • erythrocyte development Source: ZFIN
  • erythrocyte differentiation Source: ZFIN
  • heart looping Source: ZFIN
  • hematopoietic stem cell differentiation Source: ZFIN
  • intermediate mesoderm development Source: ZFIN
  • Kupffer's vesicle development Source: ZFIN
  • liver development Source: ZFIN
  • mesodermal to mesenchymal transition involved in gastrulation Source: ZFIN
  • mesoderm development Source: ZFIN
  • myeloid cell development Source: ZFIN
  • pancreas development Source: ZFIN
  • paraxial mesoderm formation Source: ZFIN
  • pronephric duct morphogenesis Source: ZFIN
  • pronephric glomerulus morphogenesis Source: ZFIN
  • pronephros development Source: ZFIN
  • regulation of BMP signaling pathway involved in heart jogging Source: ZFIN
  • regulation of endodermal cell fate specification Source: ZFIN
  • somatic muscle development Source: ZFIN
  • somite development Source: ZFIN
  • somitogenesis Source: ZFIN
  • transcription, DNA-templated Source: UniProtKB-KW
  • vasculogenesis Source: ZFIN

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
T-box containing proteinImported
Gene namesi
Name:tbx16Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990615-5 tbx16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO93303
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3585 Eukaryota
ENOG410XSTS LUCA
HOVERGENiHBG003537

Family and domain databases

CDDicd00182 TBOX, 1 hit
Gene3Di2.60.40.820, 1 hit
InterProiView protein in InterPro
IPR008967 p53-like_TF_DNA-bd
IPR036960 T-box_sf
IPR001699 TF_T-box
IPR018186 TF_T-box_CS
PANTHERiPTHR11267 PTHR11267, 1 hit
PfamiView protein in Pfam
PF00907 T-box, 1 hit
PRINTSiPR00937 TBOX
SMARTiView protein in SMART
SM00425 TBOX, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS01283 TBOX_1, 1 hit
PS01264 TBOX_2, 1 hit
PS50252 TBOX_3, 1 hit

Sequencei

Sequence statusi: Complete.

O93303-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAIRDLKHN FSLPPPPSMP GAGDSYHQGN IRMTLEDPEL WRSFHEIGTE
60 70 80 90 100
MIITKPGRRM FPHCKISLSG LVPYAKYILL VDMVPEDGLR YKWNKDKWEV
110 120 130 140 150
AGKAEPQPPY RTYLHPDSPA PGSHWMKQPV SFLKLKLTNN ALDQHGHIIL
160 170 180 190 200
HSMHRYHPRF HIVQADDLYS VRWSVFQTFT FPETSFTAVT AYQNTKITKL
210 220 230 240 250
KIDHNPFAKG FRDEGTNSKR RANRNLPDPE RVAKKMSKES THGSPRDVQP
260 270 280 290 300
SSCEALDDEH AGRKELEVKA ERYSPWGGAC DRDSGHALRP ESPLGSDHRD
310 320 330 340 350
VFSSEQLVPG QNTYQPYRFH EYGKSPSPSS SSSVGGSSAC GSAGRPSFES
360 370 380 390 400
RVLDVATVPD TDSSSKPSSA PEFSLPPHPS AGHQEYAGVL NMAITQAKPG
410 420 430 440 450
MLGTHPLYSH YSTEQSLGQW SGAAASQYPP PPPPHHHLPT EYSNQAVHHG
460 470
YHHGNVGEWS QYPLFSYSCW
Length:470
Mass (Da):52,619
Last modified:November 1, 1998 - v1
Checksum:iE45618BA2E1491E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF044977 mRNA Translation: AAC25499.1
UniGeneiDr.75456

Similar proteinsi

Entry informationi

Entry nameiO93303_DANRE
AccessioniPrimary (citable) accession number: O93303
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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