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Protein
Submitted name:

T-Box protein 4

Gene

TBX4

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

  • DNA binding Source: UniProtKB-UniRule
  • DNA binding transcription factor activity Source: InterPro
  • LIM domain binding Source: AgBase

GO - Biological processi

  • angiogenesis Source: Ensembl
  • embryonic hindlimb morphogenesis Source: AgBase
  • forelimb morphogenesis Source: AgBase
  • limb bud formation Source: AgBase
  • limb morphogenesis Source: UniProtKB
  • lung development Source: Ensembl
  • morphogenesis of an epithelium Source: Ensembl
  • regulation of gene expression Source: AgBase
  • skeletal system morphogenesis Source: UniProtKB
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
T-Box protein 4Imported
Submitted name:
T-box 4Imported
Gene namesi
Name:TBX4Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000005285
ExpressionAtlasiO93288 baseline and differential

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PDLIM7Q679P33EBI-6663926,EBI-6693710

GO - Molecular functioni

  • LIM domain binding Source: AgBase

Protein-protein interaction databases

IntActiO93288, 1 interactor

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118897
HOVERGENiHBG007310
KOiK10178
OrthoDBiEOG091G0I8R

Family and domain databases

CDDicd00182 TBOX, 1 hit
Gene3Di2.60.40.820, 1 hit
InterProiView protein in InterPro
IPR008967 p53-like_TF_DNA-bd
IPR036960 T-box_sf
IPR001699 TF_T-box
IPR018186 TF_T-box_CS
PANTHERiPTHR11267 PTHR11267, 1 hit
PfamiView protein in Pfam
PF00907 T-box, 1 hit
PRINTSiPR00937 TBOX
SMARTiView protein in SMART
SM00425 TBOX, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS01283 TBOX_1, 1 hit
PS01264 TBOX_2, 1 hit
PS50252 TBOX_3, 1 hit

Sequencei

Sequence statusi: Complete.

O93288-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQEKSLSET EEGFPTAPAP GHADSSAGSP VLGVAGGSST PLSSPQLPDP
60 70 80 90 100
EQTIENIKVY LHEKELWKKF HEAGTEMIIT KAGRRMFPSY KVKVTGMNPK
110 120 130 140 150
TKYILLIDIV PADDHRYKFC DNKWMVAGKA EPAMPGRLYV HPDSPATGAH
160 170 180 190 200
WMRQLVSFQK LKLTNNHLDP FGHIILNSMH KYQPRLHIVK ADENNAFGSK
210 220 230 240 250
NTAFCTHVFP ETSFISVTSY QNHKITQLKI ENNPFAKGFR GSDDSDLRVA
260 270 280 290 300
RLQSKEYPVI SKSIMRQRLV SSHGQLSTKP DVNPLHGSHQ TLQHYQYENG
310 320 330 340 350
AHMQFAASDT QDLSLNTFTA QRDSGLFYHC LKRRESARHL DLPCKRSYLE
360 370 380 390 400
ASSSVGDDHY FRSPPPYEQQ MLSPSYCSEV APREACMYSG SGAEIAGVPA
410 420 430 440 450
VDDLPPPPPP LSCNMWTSVA PYTSYSVQTM ETVPYQPFPA HFTATTMMPR
460 470 480 490 500
LPSIAGQGSQ PPGNSHFSVY NQLAQSQVRE RVPPSSFPRE RVHPSVCERK
510 520 530 540
PPSPHLNAAN EFLYSQSFSL SRESSLQYHS GMGTVENWTD G
Length:541
Mass (Da):60,381
Last modified:November 1, 1998 - v1
Checksum:i5744194A87CC22EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000066 Genomic DNA No translation available.
AF033670 mRNA Translation: AAC41298.1
RefSeqiNP_001025708.1, NM_001030537.1
UniGeneiGga.489

Genome annotation databases

EnsembliENSGALT00000008476; ENSGALP00000008462; ENSGALG00000005285
GeneIDi373989
KEGGigga:373989

Similar proteinsi

Entry informationi

Entry nameiO93288_CHICK
AccessioniPrimary (citable) accession number: O93288
Secondary accession number(s): E1C1W1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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