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Protein
Submitted name:

T-Box protein 4

Gene

TBX4

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • angiogenesis Source: Ensembl
  • embryonic hindlimb morphogenesis Source: AgBase
  • forelimb morphogenesis Source: AgBase
  • limb bud formation Source: AgBase
  • limb morphogenesis Source: UniProtKB
  • lung development Source: Ensembl
  • morphogenesis of an epithelium Source: Ensembl
  • regulation of gene expression Source: AgBase
  • skeletal system morphogenesis Source: Ensembl Source: UniProtKB
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
T-Box protein 4Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TBX4Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 19

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

  • actin filament Source: AgBase
  • cytoplasm Source: AgBase
  • nucleus Source: AgBase
  • stress fiber Source: AgBase
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000005285.

Interactioni

GO - Molecular functioni

  • LIM domain binding Source: AgBase

Protein-protein interaction databases

IntActiO93288. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliO93288.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118897.
HOVERGENiHBG007310.
KOiK10178.
OMAiAREACMY.
OrthoDBiEOG091G0I8R.
PhylomeDBiO93288.

Family and domain databases

CDDicd00182. TBOX. 1 hit.
Gene3Di2.60.40.820. 1 hit.
InterProiIPR008967. p53-like_TF_DNA-bd.
IPR001699. TF_T-box.
IPR018186. TF_T-box_CS.
[Graphical view]
PANTHERiPTHR11267. PTHR11267. 1 hit.
PfamiPF00907. T-box. 1 hit.
[Graphical view]
PRINTSiPR00937. TBOX.
SMARTiSM00425. TBOX. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS01283. TBOX_1. 1 hit.
PS01264. TBOX_2. 1 hit.
PS50252. TBOX_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O93288-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQEKSLSET EEGFPTAPAP GHADSSAGSP VLGVAGGSST PLSSPQLPDP
60 70 80 90 100
EQTIENIKVY LHEKELWKKF HEAGTEMIIT KAGRRMFPSY KVKVTGMNPK
110 120 130 140 150
TKYILLIDIV PADDHRYKFC DNKWMVAGKA EPAMPGRLYV HPDSPATGAH
160 170 180 190 200
WMRQLVSFQK LKLTNNHLDP FGHIILNSMH KYQPRLHIVK ADENNAFGSK
210 220 230 240 250
NTAFCTHVFP ETSFISVTSY QNHKITQLKI ENNPFAKGFR GSDDSDLRVA
260 270 280 290 300
RLQSKEYPVI SKSIMRQRLV SSHGQLSTKP DVNPLHGSHQ TLQHYQYENG
310 320 330 340 350
AHMQFAASDT QDLSLNTFTA QRDSGLFYHC LKRRESARHL DLPCKRSYLE
360 370 380 390 400
ASSSVGDDHY FRSPPPYEQQ MLSPSYCSEV APREACMYSG SGAEIAGVPA
410 420 430 440 450
VDDLPPPPPP LSCNMWTSVA PYTSYSVQTM ETVPYQPFPA HFTATTMMPR
460 470 480 490 500
LPSIAGQGSQ PPGNSHFSVY NQLAQSQVRE RVPPSSFPRE RVHPSVCERK
510 520 530 540
PPSPHLNAAN EFLYSQSFSL SRESSLQYHS GMGTVENWTD G
Length:541
Mass (Da):60,381
Last modified:November 1, 1998 - v1
Checksum:i5744194A87CC22EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000066 Genomic DNA. No translation available.
AF033670 mRNA. Translation: AAC41298.1.
RefSeqiNP_001025708.1. NM_001030537.1.
UniGeneiGga.489.

Genome annotation databases

EnsembliENSGALT00000008476; ENSGALP00000008462; ENSGALG00000005285.
GeneIDi373989.
KEGGigga:373989.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000066 Genomic DNA. No translation available.
AF033670 mRNA. Translation: AAC41298.1.
RefSeqiNP_001025708.1. NM_001030537.1.
UniGeneiGga.489.

3D structure databases

ProteinModelPortaliO93288.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO93288. 1 interactor.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000008476; ENSGALP00000008462; ENSGALG00000005285.
GeneIDi373989.
KEGGigga:373989.

Organism-specific databases

CTDi9496.

Phylogenomic databases

GeneTreeiENSGT00760000118897.
HOVERGENiHBG007310.
KOiK10178.
OMAiAREACMY.
OrthoDBiEOG091G0I8R.
PhylomeDBiO93288.

Gene expression databases

BgeeiENSGALG00000005285.

Family and domain databases

CDDicd00182. TBOX. 1 hit.
Gene3Di2.60.40.820. 1 hit.
InterProiIPR008967. p53-like_TF_DNA-bd.
IPR001699. TF_T-box.
IPR018186. TF_T-box_CS.
[Graphical view]
PANTHERiPTHR11267. PTHR11267. 1 hit.
PfamiPF00907. T-box. 1 hit.
[Graphical view]
PRINTSiPR00937. TBOX.
SMARTiSM00425. TBOX. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS01283. TBOX_1. 1 hit.
PS01264. TBOX_2. 1 hit.
PS50252. TBOX_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO93288_CHICK
AccessioniPrimary (citable) accession number: O93288
Secondary accession number(s): E1C1W1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.