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Protein
Submitted name:

Dharma

Gene

dharma

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi115 – 174HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

  • axial mesoderm formation Source: ZFIN
  • axial mesoderm morphogenesis Source: ZFIN
  • brain morphogenesis Source: ZFIN
  • determination of left/right asymmetry in lateral mesoderm Source: ZFIN
  • determination of left/right symmetry Source: ZFIN
  • developmental pigmentation Source: ZFIN
  • embryonic heart tube morphogenesis Source: ZFIN
  • embryonic pattern specification Source: ZFIN
  • eye morphogenesis Source: ZFIN
  • floor plate development Source: ZFIN
  • heart looping Source: ZFIN
  • notochord development Source: ZFIN
  • notochord formation Source: ZFIN
  • positive regulation of fibroblast growth factor receptor signaling pathway Source: ZFIN
  • regulation of BMP signaling pathway involved in heart jogging Source: ZFIN
  • somite development Source: ZFIN
  • Spemann organizer formation Source: ZFIN

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
DharmaImported
Submitted name:
NieuwkoidImported
Gene namesi
Name:dharmaImported
Synonyms:nwkImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990415-22. dharma.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 173HomeoboxInterPro annotationAdd BLAST61

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0484. Eukaryota.
ENOG4111YNP. LUCA.
HOVERGENiHBG105660.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like_sf.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR000047. HTH_motif.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00031. HTHREPRESSR.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O93236-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATQKFSNFS IDYILGDTSR QTAESPGVDH PASSQDFQGH LRKLDLLYQE
60 70 80 90 100
GCRGHCDRAA LMVNFPCPSW PGMYCCCVPV SYYQSTYYAG QPWPYAVAGC
110 120 130 140 150
ETAENHYHTI AQRPRGRIRT VFTDNQTEQL ERLFAVTDYP TVETRAELAQ
160 170 180 190
NTGLSEETVR VWFKNRRARR KRQTTCADKH ANRALEDHQE SD
Length:192
Mass (Da):22,007
Last modified:November 1, 1999 - v2
Checksum:iA75CF8E37F928C2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF098202 mRNA. Translation: AAC78640.1.
BC122095 mRNA. Translation: AAI22096.1.
AB010103 mRNA. Translation: BAA32030.2.
RefSeqiNP_571054.1. NM_130979.3.
UniGeneiDr.75841.

Genome annotation databases

GeneIDi30170.

Similar proteinsi

Entry informationi

Entry nameiO93236_DANRE
AccessioniPrimary (citable) accession number: O93236
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1999
Last modified: November 22, 2017
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)