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Protein
Submitted name:

Pr95

Gene

gag-pro

Organism
Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aspartyl proteaseUniRule annotation, Hydrolase, Protease

Keywords - Ligandi

Metal-binding, Zinc

Protein family/group databases

MEROPSiA02.009.

Names & Taxonomyi

Protein namesi
Submitted name:
Pr95Imported
Gene namesi
Name:gag-proImported
OrganismiMason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus)Imported
Taxonomic identifieri11855 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeBetaretrovirus
Virus hostiMacaca mulatta (Rhesus macaque) [TaxID: 9544]

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid proteinUniRule annotation, Virion

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3TPNX-ray1.65A608-759[»]
3TPSX-ray1.85A608-759[»]
3TPYX-ray1.75A608-759[»]
3TQ3X-ray1.85A608-759[»]
3TQ4X-ray1.60A608-759[»]
3TQ5X-ray1.40A608-759[»]
3TRLX-ray1.80A608-759[»]
3TRNX-ray1.83A608-759[»]
3TS6X-ray1.84A608-759[»]
3TSLX-ray2.20A608-759[»]
3TTAX-ray2.00A608-759[»]
ProteinModelPortaliO92810.
SMRiO92810. Positions 1-100, 574-605, 632-744, 760-866.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO92810.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini549 – 56214CCHC-typeInterPro annotationAdd
BLAST
Domaini780 – 85677Peptidase A2InterPro annotationAdd
BLAST
Domaini867 – 91145G-patchInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains CCHC-type zinc fingers.SAAS annotation
Contains peptidase A2 domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Family and domain databases

Gene3Di1.10.1200.30. 1 hit.
1.10.375.10. 1 hit.
2.40.70.10. 1 hit.
2.70.40.10. 1 hit.
4.10.60.10. 1 hit.
InterProiIPR001969. Aspartic_peptidase_AS.
IPR003322. B_retro_matrix.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
IPR000467. G_patch_dom.
IPR000721. Gag_p24.
IPR001995. Peptidase_A2_cat.
IPR021109. Peptidase_aspartic_dom.
IPR018061. Retropepsins.
IPR008916. Retrov_capsid_C.
IPR008919. Retrov_capsid_N.
IPR010999. Retrovr_matrix.
IPR001878. Znf_CCHC.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
PF01585. G-patch. 1 hit.
PF02337. Gag_p10. 1 hit.
PF00607. Gag_p24. 1 hit.
PF00077. RVP. 1 hit.
[Graphical view]
ProDomiPD004265. B_retro_matrix_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00443. G_patch. 1 hit.
SM00343. ZnF_C2HC. 2 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
SSF47836. SSF47836. 1 hit.
SSF47943. SSF47943. 1 hit.
SSF50630. SSF50630. 1 hit.
SSF51283. SSF51283. 1 hit.
SSF57756. SSF57756. 1 hit.
PROSITEiPS50175. ASP_PROT_RETROV. 1 hit.
PS00141. ASP_PROTEASE. 1 hit.
PS50174. G_PATCH. 1 hit.
PS50158. ZF_CCHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O92810-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQELSQHER YVEQLKQALK TRGVKVKYAD LLKFFDFVKD TCPWFPQEGT
60 70 80 90 100
IDIKRWRRVG DCFQDYYNTF GPEKVPVTAF SYWNLIKELI DKKEVNPQVM
110 120 130 140 150
AAVAQTEEIL KSNSQTDLTK TSQNPDLDLI SLDSDDEGAK SSSLQDKGLS
160 170 180 190 200
STKKPKRFPV LLTAQTSKDP EDPNPSEVDW DGLEDEAAKY HNPDWPPFLT
210 220 230 240 250
RPPPYNKATP SAPTVMAVVN PKEELKEKIA QLEEQIKLEE LHQALISKLQ
260 270 280 290 300
KLKTGNETVT HPDTAGGLSR TPHWPGQHIP KGKCCASREK EEQIPKDIFP
310 320 330 340 350
VTETVDGQGQ AWRHHNGFDF AVIKELKTAA SQYGATAPYT LAIVESVADN
360 370 380 390 400
WLTPTDWNTL VRAVLSGGDH LLWKSEFFEN CRDTAKRNQQ AGNGWDFDML
410 420 430 440 450
TGSGNYSSTD AQMQYDPGLF AQIQAAATKA WRKLPVKGDP GASLTGVKQG
460 470 480 490 500
PDEPFADFVH RLITTAGRIF GSAEAGVDYV KQLAYENANP ACQAAIRPYR
510 520 530 540 550
KKTDLTGYIR LCSDIGPSYQ QGLAMAAAFS GQTVKDFLNN KNKEKGGCCF
560 570 580 590 600
KCGKKGHFAK NCHEHAHNNA EPKVPGLCPR CKRGKHWANE CKSKTDNQGN
610 620 630 640 650
PIPPHQGNRV EGPAPGPETS LWGSQLCSSQ QKQPISKLTR ATPGSAGLDL
660 670 680 690 700
CSTSHTVLTP EMGPQALSTG IYGPLPPNTF GLILGRSSIT MKGLQVYPGV
710 720 730 740 750
IDNDYTGEIK IMAKAVNNIV TVSQGNRIAQ LILLPLIETD NKVQQPYRGQ
760 770 780 790 800
GSFGSSDIYW VQPITCQKPS LTLWLDDKMF TGLIDTGADV TIIKLEDWPP
810 820 830 840 850
NWPITDTLTN LRGIGQSNNP KQSSKYLTWR DKENNSGLIK PFVIPNLPVN
860 870 880 890 900
LWGRDLLSQM KIMMCSPNDI VTAQMLAQGY SPGKGLGKKE NGILHPIPNQ
910
GQSNKKGFGN F
Length:911
Mass (Da):100,648
Last modified:December 1, 2001 - v2
Checksum:iD9B65A6070A3CA7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033815 Genomic RNA. Translation: AAC82574.1.
RefSeqiNP_056892.1. NC_001550.1.

Genome annotation databases

GeneIDi2746973.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033815 Genomic RNA. Translation: AAC82574.1.
RefSeqiNP_056892.1. NC_001550.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3TPNX-ray1.65A608-759[»]
3TPSX-ray1.85A608-759[»]
3TPYX-ray1.75A608-759[»]
3TQ3X-ray1.85A608-759[»]
3TQ4X-ray1.60A608-759[»]
3TQ5X-ray1.40A608-759[»]
3TRLX-ray1.80A608-759[»]
3TRNX-ray1.83A608-759[»]
3TS6X-ray1.84A608-759[»]
3TSLX-ray2.20A608-759[»]
3TTAX-ray2.00A608-759[»]
ProteinModelPortaliO92810.
SMRiO92810. Positions 1-100, 574-605, 632-744, 760-866.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiA02.009.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2746973.

Miscellaneous databases

EvolutionaryTraceiO92810.

Family and domain databases

Gene3Di1.10.1200.30. 1 hit.
1.10.375.10. 1 hit.
2.40.70.10. 1 hit.
2.70.40.10. 1 hit.
4.10.60.10. 1 hit.
InterProiIPR001969. Aspartic_peptidase_AS.
IPR003322. B_retro_matrix.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
IPR000467. G_patch_dom.
IPR000721. Gag_p24.
IPR001995. Peptidase_A2_cat.
IPR021109. Peptidase_aspartic_dom.
IPR018061. Retropepsins.
IPR008916. Retrov_capsid_C.
IPR008919. Retrov_capsid_N.
IPR010999. Retrovr_matrix.
IPR001878. Znf_CCHC.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
PF01585. G-patch. 1 hit.
PF02337. Gag_p10. 1 hit.
PF00607. Gag_p24. 1 hit.
PF00077. RVP. 1 hit.
[Graphical view]
ProDomiPD004265. B_retro_matrix_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00443. G_patch. 1 hit.
SM00343. ZnF_C2HC. 2 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
SSF47836. SSF47836. 1 hit.
SSF47943. SSF47943. 1 hit.
SSF50630. SSF50630. 1 hit.
SSF51283. SSF51283. 1 hit.
SSF57756. SSF57756. 1 hit.
PROSITEiPS50175. ASP_PROT_RETROV. 1 hit.
PS00141. ASP_PROTEASE. 1 hit.
PS50174. G_PATCH. 1 hit.
PS50158. ZF_CCHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Appendix 2: Retroviral taxonomy, protein structure, sequences, and genetic maps."
    Petropoulos C.J.
    (In) Coffin, J.M. (eds.); RETROVIRUSES, pp.757-0, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, NY, USA (1997)
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Chappey C.
    Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize in-Line Attack and Inversion."
    Barabas O., Nemeth V., Bodor A., Perczel A., Rosta E., Kele Z., Zagyva I., Szabadka Z., Grolmusz V.I., Wilmanns M., Vertessy B.G.
    Submitted (SEP-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 608-759.
  4. "Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion."
    Barabas O., Nemeth V., Bodor A., Perczel A., Rosta E., Kele Z., Zagyva I., Szabadka Z., Grolmusz V.I., Wilmanns M., Vertessy B.G.
    Submitted (SEP-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 608-759.

Entry informationi

Entry nameiO92810_MPMV
AccessioniPrimary (citable) accession number: O92810
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: December 1, 2001
Last modified: April 13, 2016
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.