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Protein

Replication enhancer

Gene

AC3

Organism
Tomato leaf curl New Delhi virus-[Lucknow]
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enhances infectivity and symptom expression.UniRule annotation
Increases viral DNA accumulation.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interactionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Replication enhancerUniRule annotation
Short name:
REnUniRule annotation
Gene namesi
Name:AC3Imported
OrganismiTomato leaf curl New Delhi virus-[Lucknow]Imported
Taxonomic identifieri223348 [NCBI]
Taxonomic lineageiVirusesssDNA virusesGeminiviridaeBegomovirus

Interactioni

Subunit structurei

Homooligomer. Interacts with the replication-associated protein (REP). Interacts with host proliferating cell nuclear antigen (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1), and may thereby deregulate the host cell cycle. Oligomerization and interaction with PCNA are necessary for optimal replication enhancement.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the geminiviridae replication enhancer protein family.UniRule annotation

Family and domain databases

InterProiIPR000657. Gemini_AL3.
[Graphical view]
PfamiPF01407. Gemini_AL3. 1 hit.
[Graphical view]
PRINTSiPR00231. GEMCOATAL3.
ProDomiPD001172. Gemini_AL3. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

O91274-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITDSRTGEY ITADRAESGV YTWEIRNPLY FKILKHDSRP FLTQHDIIKI
60 70 80 90 100
QIQFNHNLRK ALGLHKCFLT FQIWTGLRPQ IGIFLRVFKT QVLKYLDMLG
110 120 130
VIGIYNVIRA VYHVLDNVLE QTIDVWTSYD IKLDIY
Length:136
Mass (Da):16,106
Last modified:May 1, 1999 - v2
Checksum:iC31E1DF9A9A548C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y16421 Genomic DNA. Translation: CAA76214.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y16421 Genomic DNA. Translation: CAA76214.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000657. Gemini_AL3.
[Graphical view]
PfamiPF01407. Gemini_AL3. 1 hit.
[Graphical view]
PRINTSiPR00231. GEMCOATAL3.
ProDomiPD001172. Gemini_AL3. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. Hallan V., Saxena S.
    Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO91274_9GEMI
AccessioniPrimary (citable) accession number: O91274
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: May 1, 1999
Last modified: June 8, 2016
This is version 30 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.