O90777 (O90777_9PLVG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
HIV-1 protease EMBL CAA09312.1

Gene names

Name:

HIV-1 protease EMBL CAA09312.1

Organism

Human immunodeficiency virus EMBL CAA09312.1

Taxonomic identifier

12721 [NCBI]

Taxonomic lineage

Viruses › Retro-transcribing viruses › Retroviridae › Orthoretrovirinae › Lentivirus › Primate lentivirus group › unclassified Primate lentivirus group

Protein attributes

Sequence length	99 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 peptidase A2 domain. SAAS SAAS009007

Ontologies

Keywords
Molecular function	Aspartyl protease RuleBase RU000453 Hydrolase Protease
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aspartic-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAA09312.1
	Non-terminal residue	99	1	EMBL CAA09312.1

Sequences

	Sequence		Length	Mass (Da)
	O90777 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 672070B055E66B52	FASTA	99	10,725
	10 20 30 40 50 60 PQVTLWQRPI VTIKIGGQLK EALLDTGADD TVLEEMSLPG KWKPKMIGGI GGFIKVRQYD 70 80 90 QVSIEICGHK AIGTVLIGPT PVNIIGRNLL TQLGCTLNF

References

[1]	"Natural polymorphism of human immunodeficiency virus type 1 protease." Servais J.A. AIDS 0:0-0(0) Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Variant human immunodeficiency virus type 1 proteases and response to combination therapy including a protease inhibitor." Servais J., Lambert C., Fontaine E., Plesseria J.M., Robert I., Arendt V., Staub T., Schneider F., Hemmer R., Burtonboy G., Schmit J.C. Antimicrob. Agents Chemother. 45:893-900(2001) [PubMed: 11181376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Comparison of DNA sequencing and a line probe assay for detection of human immunodeficiency virus Type 1 in patients failing highly active antiretroviral therapy." Servais J., Lambert C., Fontaine E., Plesseria J.M., Robert I., Arendt V., Staub T., Schneider F., Hemmer R., Burtonboy G., Schmit J.C. J. Clin. Microbiol. 39:454-459(2001) [PubMed: 11158089] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[4]	Servais J.A. Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ010714 mRNA. Translation: CAA09312.1.
3D structure databases
ProteinModelPortal	O90777.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR018061. Pept_A2A_retrovirus_sg. IPR001995. Peptidase_A2_cat. IPR021109. Peptidase_aspartic. IPR001969. Peptidase_aspartic_AS. IPR009007. Peptidase_aspartic_catalytic. [Graphical view]
Gene3D	G3DSA:2.40.70.10. Pept_Aspartc_cat. 1 hit.
Pfam	PF00077. RVP. 1 hit. [Graphical view]
SUPFAM	SSF50630. Pept_Aspartic. 1 hit.
PROSITE	PS50175. ASP_PROT_RETROV. 1 hit. PS00141. ASP_PROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O90777_9PLVG

Accession

Primary (citable) accession number: O90777

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	November 16, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)