Insulin receptor substrate 2 - Rattus norvegicus (Rat)

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Unreviewed, UniProtKB/TrEMBL O88948 (O88948_RAT)

Last modified January 19, 2010. Version 34. History...

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Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Insulin receptor substrate 2 EMBL AAC36726.1

Gene names

Name:	Irs2 RGD 69316
Synonyms:	IRS-2 EMBL AAC36726.1

Organism

Rattus norvegicus (Rat) EMBL AAC36726.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	156 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Receptor EMBL AAC36726.1
Gene Ontology (GO)
Biological process	brain development Inferred from electronic annotation. Source: Compara cell proliferation Inferred from electronic annotation. Source: Compara insulin receptor signaling pathway Inferred from mutant phenotype. Source: RGD mammary gland development Inferred from electronic annotation. Source: Compara negative regulation of plasma membrane long-chain fatty acid transport Inferred from electronic annotation. Source: Compara positive regulation of cell migration Inferred from electronic annotation. Source: Compara positive regulation of fatty acid beta-oxidation Inferred from electronic annotation. Source: Compara positive regulation of glucose import Inferred from electronic annotation. Source: Compara positive regulation of glucose metabolic process Inferred from electronic annotation. Source: Compara positive regulation of glycogen biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of mesenchymal cell proliferation Inferred from electronic annotation. Source: Compara
Molecular function	insulin receptor binding Inferred from mutant phenotype. Source: RGD phosphoinositide 3-kinase binding Inferred from mutant phenotype. Source: RGD protein domain specific binding Inferred from physical interaction. Source: RGD protein kinase binding Inferred from electronic annotation. Source: Compara protein phosphatase binding Inferred from physical interaction. Source: RGD receptor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

1

EMBL AAC36726.1

Non-terminal residue

1

EMBL AAC36726.1

Sequences

Sequence

Length

Mass (Da)

Tools

O88948-1 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 8A5299EB7157CAC6
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156

16,152

        10         20         30         40         50         60 
ERLEPQATPG AGTFGAAGGS HTQPHHSAVP SSMRPSGIVG RPEGFLGQRC RAVRPTRLSL 

        70         80         90        100        110        120 
EGLQTLPSMQ EYPLPTEPKS PGEYINIDFG EGGTRLSPPA PPLLASAASS SSLLSASSPA 

       130        140        150 
SSLGSGTPGT SRDSRQRSPL SDYMNLDFSS PKSPKP

References

[1]	Vassen L., Wegrzyn W., Klein-Hitpass L. Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Sprague-Dawley EMBL AAC36726.1. Tissue: Brain EMBL AAC36726.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF087674 mRNA. Translation: AAC36726.1.
IPI	IPI00390437.
UniGene	Rn.10718
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000032918; ENSRNOP00000036862; ENSRNOG00000023509; Rattus norvegicus. [Genome view]
UCSC	C25A1.7.3. c. elegans.
Phylogenomic databases
HOVERGEN	O88948.
Gene expression databases
Genevestigator	O88948.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

O88948_RAT

Accession

Primary (citable) accession number: O88948

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	January 19, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information