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Protein

CD160 antigen

Gene

Cd160

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Receptor showing broad specificity for both classical and non-classical MHC class I molecules.

GO - Molecular functioni

GO - Biological processi

  • defense response to Gram-negative bacterium Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Names & Taxonomyi

Protein namesi
Recommended name:
CD160 antigen
Alternative name(s):
Natural killer cell receptor BY55
CD_antigen: CD160
Gene namesi
Name:Cd160
Synonyms:By55
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1860383. Cd160.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000001454528 – 160CD160 antigenAdd BLAST133
PropeptideiPRO_0000014546161 – 185Removed in mature formSequence analysisAdd BLAST25

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi47 ↔ 115PROSITE-ProRule annotation
Disulfide bondi64 ↔ 71PROSITE-ProRule annotation
Glycosylationi138N-linked (GlcNAc...)Sequence analysis1
Glycosylationi156N-linked (GlcNAc...)Sequence analysis1
Lipidationi160GPI-anchor amidated serineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

PaxDbiO88875.
PRIDEiO88875.

PTM databases

PhosphoSitePlusiO88875.

Expressioni

Gene expression databases

BgeeiENSMUSG00000038304.
CleanExiMM_CD160.
ExpressionAtlasiO88875. baseline and differential.
GenevisibleiO88875. MM.

Interactioni

Subunit structurei

Homomultimer; disulfide-linked.By similarity

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliO88875.
SMRiO88875.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 125Ig-like V-typeAdd BLAST98

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

eggNOGiENOG410IX7D. Eukaryota.
ENOG411156J. LUCA.
GeneTreeiENSGT00390000007258.
HOGENOMiHOG000095285.
HOVERGENiHBG018849.
InParanoidiO88875.
KOiK06542.
OMAiGTYQCCA.
OrthoDBiEOG091G0NW8.
TreeFamiTF338321.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O88875-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRILMAPGQ SCCALAILLA IVNFQHGGCI HVTSSASQKG GRLDLTCTLW
60 70 80 90 100
HKKDEAEGLI LFWCKDNPWN CSPETNLEQL RVKRDPETDG ITEKSSQLVF
110 120 130 140 150
TIEQATPSDS GTYQCCARSQ KPEIYIHGHF LSVLVTGNHT EIRQRQRSHP
160 170 180
DFSHINGTLS SGFLQVKAWG MLVTSLVALQ ALYTL
Length:185
Mass (Da):20,570
Last modified:October 3, 2012 - v2
Checksum:i37071CB339E032E2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti45L → P in AAC62227 (PubMed:9743336).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF060982 mRNA. Translation: AAC62227.1.
AK042093 mRNA. Translation: BAC31162.1.
AK145332 mRNA. Translation: BAE26372.1.
AC127297 Genomic DNA. No translation available.
CCDSiCCDS17648.1.
RefSeqiNP_001156968.1. NM_001163496.1.
NP_061237.3. NM_018767.3.
UniGeneiMm.34693.

Genome annotation databases

EnsembliENSMUST00000047702; ENSMUSP00000037466; ENSMUSG00000038304.
ENSMUST00000107074; ENSMUSP00000102689; ENSMUSG00000038304.
GeneIDi54215.
KEGGimmu:54215.
UCSCiuc008qof.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF060982 mRNA. Translation: AAC62227.1.
AK042093 mRNA. Translation: BAC31162.1.
AK145332 mRNA. Translation: BAE26372.1.
AC127297 Genomic DNA. No translation available.
CCDSiCCDS17648.1.
RefSeqiNP_001156968.1. NM_001163496.1.
NP_061237.3. NM_018767.3.
UniGeneiMm.34693.

3D structure databases

ProteinModelPortaliO88875.
SMRiO88875.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSitePlusiO88875.

Proteomic databases

PaxDbiO88875.
PRIDEiO88875.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000047702; ENSMUSP00000037466; ENSMUSG00000038304.
ENSMUST00000107074; ENSMUSP00000102689; ENSMUSG00000038304.
GeneIDi54215.
KEGGimmu:54215.
UCSCiuc008qof.2. mouse.

Organism-specific databases

CTDi11126.
MGIiMGI:1860383. Cd160.

Phylogenomic databases

eggNOGiENOG410IX7D. Eukaryota.
ENOG411156J. LUCA.
GeneTreeiENSGT00390000007258.
HOGENOMiHOG000095285.
HOVERGENiHBG018849.
InParanoidiO88875.
KOiK06542.
OMAiGTYQCCA.
OrthoDBiEOG091G0NW8.
TreeFamiTF338321.

Miscellaneous databases

PROiO88875.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038304.
CleanExiMM_CD160.
ExpressionAtlasiO88875. baseline and differential.
GenevisibleiO88875. MM.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBY55_MOUSE
AccessioniPrimary (citable) accession number: O88875
Secondary accession number(s): Q8C9H4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: October 3, 2012
Last modified: November 2, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.