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Protein

Testis-specific Y-encoded-like protein 1

Gene

Tspyl1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-specific Y-encoded-like protein 1
Short name:
TSPY-like protein 1
Gene namesi
Name:Tspyl1
Synonyms:Tspyl
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1298395. Tspyl1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001856711 – 379Testis-specific Y-encoded-like protein 1Add BLAST379

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki109Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

EPDiO88852.
MaxQBiO88852.
PaxDbiO88852.
PeptideAtlasiO88852.
PRIDEiO88852.

PTM databases

iPTMnetiO88852.
PhosphoSitePlusiO88852.

Expressioni

Tissue specificityi

Highly expressed in testis, ovary, liver, spleen, brain, kidney, prostate, lung, and heart. Low expression in liver.1 Publication

Developmental stagei

Detected in embryo at 10.5 dpc.1 Publication

Gene expression databases

BgeeiENSMUSG00000047514.
CleanExiMM_TSPYL1.
GenevisibleiO88852. MM.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063051.

Structurei

3D structure databases

ProteinModelPortaliO88852.
SMRiO88852.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1508. Eukaryota.
ENOG410XQRX. LUCA.
GeneTreeiENSGT00530000062882.
HOGENOMiHOG000004793.
HOVERGENiHBG014779.
InParanoidiO88852.
KOiK11284.
OMAiIWHPGHE.
OrthoDBiEOG091G00YT.
PhylomeDBiO88852.
TreeFamiTF313386.

Family and domain databases

InterProiView protein in InterPro
IPR037231. NAP-like_sf.
IPR002164. NAP_family.
PANTHERiPTHR11875. PTHR11875. 1 hit.
PfamiView protein in Pfam
PF00956. NAP. 1 hit.
SUPFAMiSSF143113. SSF143113. 1 hit.

Sequencei

Sequence statusi: Complete.

O88852-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPERDEGT PVPDSRGHCD ADTVSGTPDR RPLLGEEKAV TGEGRAGIVG
60 70 80 90 100
SPAPRDVEGL VPQIRVAAAR QGESPPSVRG PAAAVFVTPK YVEKAQETRG
110 120 130 140 150
AESQARDVKT EPGTVAAAAE KSEVATPGSE EVMEVEQKPA GEEMEMLEAS
160 170 180 190 200
GGVREAPEEA GPWHLGIDLR RNPLEAIQLE LDTVNAQADR AFQHLEQKFG
210 220 230 240 250
RMRRHYLERR NYIIQNIPGF WMTAFRNHPQ LSAMIRGRDA EMLRYVTSLE
260 270 280 290 300
VKELRHPKTG CKFKFFFRRN PYFRNKLIVK EYEVRSSGRV VSLSTPIIWR
310 320 330 340 350
RGHEPQSFIR RNQDLICSFF TWFSDHSLPE SDRIAEIIKE DLWPNPLQYY
360 370
LCREGIRRPR RRPIREPVEI PRPFGFQSG
Length:379
Mass (Da):42,994
Last modified:November 1, 1998 - v1
Checksum:i9286C9CAA557FC2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF042180 mRNA. Translation: AAC62383.1.
AK053812 mRNA. Translation: BAC35536.1.
AK159432 mRNA. Translation: BAE35079.1.
AK166805 mRNA. Translation: BAE39033.1.
AK166893 mRNA. Translation: BAE39098.1.
BC011213 mRNA. Translation: AAH11213.1.
CCDSiCCDS23777.1.
RefSeqiNP_033459.1. NM_009433.3.
UniGeneiMm.20445.

Genome annotation databases

EnsembliENSMUST00000061372; ENSMUSP00000063051; ENSMUSG00000047514.
GeneIDi22110.
KEGGimmu:22110.
UCSCiuc007eut.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiTSYL1_MOUSE
AccessioniPrimary (citable) accession number: O88852
Secondary accession number(s): Q3TKW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome