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Protein
Submitted name:

G protein-coupled receptor

Gene
N/A
Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptorImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 48HelicalSequence analysisAdd BLAST26
Transmembranei60 – 80HelicalSequence analysisAdd BLAST21
Transmembranei100 – 122HelicalSequence analysisAdd BLAST23
Transmembranei142 – 161HelicalSequence analysisAdd BLAST20
Transmembranei181 – 208HelicalSequence analysisAdd BLAST28
Transmembranei249 – 265HelicalSequence analysisAdd BLAST17
Transmembranei285 – 308HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO88820.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000017317.

Structurei

3D structure databases

ProteinModelPortaliO88820.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 305G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST267

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000017249.
HOVERGENiHBG007549.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002120. TRH_rcpt_1.
[Graphical view]
PANTHERiPTHR24243:SF51. PTHR24243:SF51. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01654. TRHRECEPTOR2.
PR01846. TRHRFAMILY.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O88820-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGPSNVSLI HGDTTLGLPE YKVVSVFLVL LVCTLGIVGN AMVILVVLTS
60 70 80 90 100
RDMHTPTNCY LVSLALADLL VLLAAGLPNV SDSLVGHWIY GRAGCLGITY
110 120 130 140 150
FQYLGINVSS FSILAFTVER YIAICHPLRA QTVCTVARAK RIIAGIWGVT
160 170 180 190 200
SLYCLLWFFL VDLNVRDNQR LECGYKVPRG LYLPIYLLDF AVFFIGPLLV
210 220 230 240 250
TLVLYGLIGR ILFQSPLSQE AWQKERQPHG QSEAAPGNCS RAKSSRKQAT
260 270 280 290 300
RMLAVVVLLF AVLWTPYRTL VLLNSFVAQP FLDPWVLLFC RTCVYTNSAV
310 320 330 340 350
NPVVYSLMSQ KFRAAFLKLC WCRAAGPQRR AARVLTSNYS AAQETSVGTE

KM
Length:352
Mass (Da):39,000
Last modified:November 1, 1998 - v1
Checksum:iB8A0D0A4375E7236
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB015645 mRNA. Translation: BAA33437.1.
PIRiJE0296.
UniGeneiRn.30031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB015645 mRNA. Translation: BAA33437.1.
PIRiJE0296.
UniGeneiRn.30031.

3D structure databases

ProteinModelPortaliO88820.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000017317.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiO88820.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000017249.
HOVERGENiHBG007549.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002120. TRH_rcpt_1.
[Graphical view]
PANTHERiPTHR24243:SF51. PTHR24243:SF51. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01654. TRHRECEPTOR2.
PR01846. TRHRFAMILY.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO88820_RAT
AccessioniPrimary (citable) accession number: O88820
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.