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O88799

- ZAN_MOUSE

UniProt

O88799 - ZAN_MOUSE

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Protein
Zonadhesin
Gene
Zan
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.

GO - Biological processi

  1. cell adhesion Source: UniProtKB-KW
  2. regulation of binding of sperm to zona pellucida Source: MGI
Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Names & Taxonomyi

Protein namesi
Recommended name:
Zonadhesin
Gene namesi
Name:Zan
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:106656. Zan.

Subcellular locationi

Cell membrane; Single-pass type I membrane protein
Note: Exclusively on the apical region of the sperm head.

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini18 – 53105293Extracellular Reviewed prediction
Add
BLAST
Transmembranei5311 – 533727Helical; Reviewed prediction
Add
BLAST
Topological domaini5338 – 537639Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717 Reviewed prediction
Add
BLAST
Chaini18 – 53765359Zonadhesin
PRO_0000007784Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi339 – 3391N-linked (GlcNAc...) Reviewed prediction
Glycosylationi499 – 4991N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1216 – 12161N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1239 – 12391N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1314 – 13141N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1814 – 18141N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1908 – 19081N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1933 – 19331N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2028 – 20281N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2111 – 21111N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2142 – 21421N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2332 – 23321N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2533 – 25331N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2575 – 25751N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2692 – 26921N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2812 – 28121N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3052 – 30521N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3065 – 30651N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3144 – 31441N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3172 – 31721N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3288 – 32881N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3292 – 32921N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3782 – 37821N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4005 – 40051N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4136 – 41361N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4243 – 42431N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4254 – 42541N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4335 – 43351N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4376 – 43761N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4586 – 45861N-linked (GlcNAc...) Reviewed prediction
Glycosylationi5136 – 51361N-linked (GlcNAc...) Reviewed prediction
Glycosylationi5252 – 52521N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi5263 ↔ 5274 By similarity
Disulfide bondi5268 ↔ 5283 By similarity
Disulfide bondi5285 ↔ 5294 By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiO88799.
PRIDEiO88799.

PTM databases

PhosphoSiteiO88799.

Expressioni

Tissue specificityi

In testis, primarily in haploid spermatids.

Gene expression databases

CleanExiMM_ZAN.
GenevestigatoriO88799.

Interactioni

Subunit structurei

Probably forms covalent oligomers.

Structurei

3D structure databases

ProteinModelPortaliO88799.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 210166MAM 1
Add
BLAST
Domaini215 – 374160MAM 2
Add
BLAST
Domaini377 – 542166MAM 3
Add
BLAST
Domaini1171 – 122050TIL 1
Add
BLAST
Domaini1227 – 127549VWFC 1
Add
BLAST
Domaini1281 – 1500220VWFD 1
Add
BLAST
Domaini1555 – 160854TIL 2
Add
BLAST
Domaini1609 – 166456VWFC 2
Add
BLAST
Domaini1670 – 1887218VWFD 2
Add
BLAST
Domaini1941 – 199555TIL 3
Add
BLAST
Domaini1996 – 205257VWFC 3
Add
BLAST
Domaini2057 – 2273217VWFD 3
Add
BLAST
Domaini2340 – 239859TIL 4
Add
BLAST
Domaini2399 – 245456VWFC 4
Add
BLAST
Domaini2460 – 251859TIL 5
Add
BLAST
Domaini2519 – 257456VWFC 5
Add
BLAST
Domaini2580 – 263859TIL 6
Add
BLAST
Domaini2639 – 269456VWFC 6
Add
BLAST
Domaini2700 – 275859TIL 7
Add
BLAST
Domaini2759 – 281456VWFC 7
Add
BLAST
Domaini2820 – 287859TIL 8
Add
BLAST
Domaini2879 – 293456VWFC 8
Add
BLAST
Domaini2940 – 299859TIL 9
Add
BLAST
Domaini2999 – 305456VWFC 9
Add
BLAST
Domaini3060 – 311859TIL 10
Add
BLAST
Domaini3119 – 317456VWFC 10
Add
BLAST
Domaini3180 – 323859TIL 11
Add
BLAST
Domaini3239 – 329456VWFC 11
Add
BLAST
Domaini3300 – 335556TIL 12
Add
BLAST
Domaini3356 – 341156VWFC 12
Add
BLAST
Domaini3417 – 347559TIL 13
Add
BLAST
Domaini3476 – 353156VWFC 13
Add
BLAST
Domaini3537 – 359559TIL 14
Add
BLAST
Domaini3596 – 365156VWFC 14
Add
BLAST
Domaini3657 – 371559TIL 15
Add
BLAST
Domaini3716 – 377156VWFC 15
Add
BLAST
Domaini3777 – 383559TIL 16
Add
BLAST
Domaini3836 – 389156VWFC 16
Add
BLAST
Domaini3893 – 395159TIL 17
Add
BLAST
Domaini3952 – 400756VWFC 17
Add
BLAST
Domaini4029 – 408759TIL 18
Add
BLAST
Domaini4088 – 414356VWFC 18
Add
BLAST
Domaini4149 – 420759TIL 19
Add
BLAST
Domaini4208 – 426255VWFC 19
Add
BLAST
Domaini4264 – 432259TIL 20
Add
BLAST
Domaini4323 – 437856VWFC 20
Add
BLAST
Domaini4384 – 444259TIL 21
Add
BLAST
Domaini4443 – 449856VWFC 21
Add
BLAST
Domaini4504 – 456259TIL 22
Add
BLAST
Domaini4563 – 461856VWFC 22
Add
BLAST
Domaini4624 – 468259TIL 23
Add
BLAST
Domaini4683 – 473856VWFC 23
Add
BLAST
Domaini4744 – 480259TIL 24
Add
BLAST
Domaini4803 – 485856VWFC 24
Add
BLAST
Domaini4864 – 5065202VWFD 4
Add
BLAST
Domaini5150 – 520354TIL 25
Add
BLAST
Domaini5204 – 525855VWFC 25
Add
BLAST
Domaini5259 – 529537EGF-like
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni547 – 117062480 X heptapeptide repeats (approximate) (mucin-like domain)
Add
BLAST

Domaini

The MAM domains probably mediates sperm adhesion to the zona pellucida.
During sperm migration through the reproductive tracts, the mucin-like domain might inhibit inappropriate trapping of spermatozoa or promoting adhesion to the oviductal isthmus.
The VWFD domain 2 may mediate covalent oligomerization By similarity.

Sequence similaritiesi

Contains 1 EGF-like domain.
Contains 3 MAM domains.
Contains 25 VWFC domains.
Contains 4 VWFD domains.

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG12793.
HOVERGENiHBG003977.
PhylomeDBiO88799.

Family and domain databases

InterProiIPR008985. ConA-like_lec_gl_sf.
IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR003645. Fol_N.
IPR000998. MAM_dom.
IPR002919. TIL_dom.
IPR025615. TILa_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR001007. VWF_C.
IPR001846. VWF_type-D.
[Graphical view]
PfamiPF00629. MAM. 3 hits.
PF01826. TIL. 25 hits.
PF12714. TILa. 25 hits.
PF00094. VWD. 4 hits.
[Graphical view]
SMARTiSM00832. C8. 4 hits.
SM00181. EGF. 2 hits.
SM00274. FOLN. 20 hits.
SM00137. MAM. 3 hits.
SM00214. VWC. 17 hits.
SM00216. VWD. 4 hits.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 3 hits.
SSF57567. SSF57567. 25 hits.
PROSITEiPS00022. EGF_1. 1 hit.
PS01186. EGF_2. 18 hits.
PS50026. EGF_3. 1 hit.
PS00740. MAM_1. 1 hit.
PS50060. MAM_2. 3 hits.
PS51233. VWFD. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O88799-1 [UniParc]FASTAAdd to Basket

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MALPVWTLML LVGAAWGQEQ VPAWRPNSPD LGPMVHTSRE DSILSKCDFE     50
DNSRPFCDWS QMSADDGDWI RTTGPSLTGT SGPPGGYPNG EGYYLHMDPK 100
TFPQGGVARL RSPDIWEQGP LCVHFAFHMF GLSWGAQLRL LLLRGRKHLR 150
PYVLWKHVNT QSPSWMPTTV TVPADHDIPS WLMFEGMRGN TAYLDISLDG 200
LSIQRGTCNQ VCMSQMCTFD TLNDLCGWSW VPTATGAKWT QKKGPTGKQG 250
VGPAEDFSNP GNGYYMLLDS TNARPGQKAV LLSPLSHSRG CMTLSFHYIM 300
HGQGHEEGLF VYATFLGNIR KYTLFSGHPG PDWQAVSVNY TGQGQIQFMV 350
VGMFGNIPEP AIAVDAISIA PCGESFPQCD FEDRVHPFCD WNQVYGDMGH 400
WSWGSKSVPT LIAGSPREFP YGGEHYIFFD SVKLSQEGQS ARLVSPPFCA 450
PGGICVEFAY HMYGLGKGTT LKLLLGSPAG SSPIPLWNRV GSQSSGWMNS 500
SVTIPKGYQQ PMQLFIEATR GTSTAFVVAL NFILISHGPC RVLLQTEIPS 550
SPLLPPTGPS ESTVPTLPME QPTSPTKATT VTIEIPTTPT EEATIPTETT 600
TVPTEVINVS PKETSIPPEV TIPTEVITVS PEEIISPTEV TPVPTDVTAA 650
YVEATNASPE ETSVPPEVTI LTEVTTVSPE ETTVPTEVPI VLIEATAFPT 700
GETTLYTEVP TVPTEVTGVH TEVTNVSPEE TSVPTEETIS TEVTTVSPEE 750
TTVPTEVPIV LIEATASPTG EITLYTEVPT VPTEVTGVHT EVTNVSPEET 800
SVPTEETIST EVTTVSPEET TLPTEVPTVS TEVTNVSPEE TSVPPEETIL 850
TTLYTEVPTV PTEVTGVHTE VTNVSPEETS VPTEETISTE VTTVSPEETT 900
LPTEVPTVST EVTNVSPEET SVPPEETILT EITTVSPEET VFPIEGTTLP 950
TEVLTVPIEV TTFPTGETTV PTEVPTVSTE MTGVHTEVTT VFPEETSIPT 1000
EVATVLPASI PPEETTTPTE VTTTPPEETT IPAEVTTVPP ASIPPEETAS 1050
LTEVTTTPPE ETTTPTEVTT VPPEKTTIPT EVTTVPPASI FPEETTVPPE 1100
ETTIASEETT VSTQETTLLT EQSAVTQTSI ACRPPCPSPP LMPIGPLLSK 1150
PPGVSMFSLA PTTGVSTTES CPPNAHIELC ACPASCESPK PSCQPPCIPG 1200
CVCNPGFLFS NNQCINESSC NCPYNNKHYK PGEEWFTPNC TERCRCLPGS 1250
LMECQISQCG THTVCQLKSD QYQCEPYGKA TCLVYGDLHF VTFDERHIGF 1300
TGTCTYILTQ TCSNSTDHFF RITANTEERG VEGVSCLDKV VISLPETTVT 1350
MISGRHTLIG DQEVTLPAIL SDDTYVGLSG RFVELRTTFG LRVRWDGDQQ 1400
LFVTVSSTFS GKLCGFCGNY DGDSSNDNLK SDGMMTHDEE ELRLSWQVEE 1450
DEDKDWVSSR CQKKKNPPSC DAALGSTMSG PKLCGQLVNP SGPFEACLLH 1500
LKASSFLDNC VTDMCSFQGL QQKLCARMSA MTATCQDAGY PVKPWREPQF 1550
CPLVCPKNSR YSLCAKPCPE TCHPISTTQH CSDKCVEGCE CDPGFILSGS 1600
ECVPSSQCGC TSFQGRYFKL QEQWFNPDCK EICTCESHNH ILCKPWKCKA 1650
QEACSYKNGV LGCHAQGAAT CMVSGDPHYL TFDGALHHFM GTCTYVLTQP 1700
CWSKSQENNF VVSATNEIHD GNLEVSYVKA VHVQVFDLKI SMFKGQKVVL 1750
NNQRVVLPVW PSQGRVTIRL SGIFVLLYTN FGLQVRYDGR HLVEVTVPSS 1800
YTGSLCGLCG NYNNNSMDDN LRADMKPAGN SLLLGAAWKI LEASDPGCFL 1850
AGGKPSRCAD SDMDDVWTKK CAILMNPLGP FSNCHEAVPP QASFSSCVYG 1900
QCETNGDNLT FCHSLQAYAS LCAQAGQVTT WRNSTFCPMR CPPRSSYNPC 1950
ANSCPATCLT LSTPRDCPTL PCVEGCECQS GHILSGTTCV PLRQCGCSDQ 2000
DGSYHLLGES WYTEKTCTTL CTCSAHSNIT CSPTACKANH VCLRQEGLLR 2050
CAAEMGECRI SEDSQIVSFD DHSHPIQDTC TYILVKVCHP NTNMPFFMIS 2100
AKTDINTNGK NKTFGVYQLY IDIFNFHITL QKDHLVLISL INDSIVTLPT 2150
TTHIPGVSVM TEDVYTIVTI KDEIQVKFES NNFLDVKIPA SSNGKVCGVC 2200
GNFNGEEEDE LMTPSGELAE DEQEFMNSWK DKSMDPNCQK IEGQNLQVEQ 2250
QEIMNGKCRP IDFEKAQANC QTALQGPAWA HCSSRVPIKP FLLKCMNSFC 2300
EFRELFRALC DSLQSFEDAC QNQGLKPPIW RNSSFCPLEC PAHSHYTNCL 2350
PSCPPSCLDP DSRCEGSGHK VPATCREGCI CQPDYVLLND KCVLRSHCGC 2400
KDAQGVFIPA GKTWISEDCT QSCTCMKGSM RCWDFQCPPG TYCKNSNDGS 2450
SNCVKISLQC PAHSKFTDCL PPCHPSCSDP DGHCEGISTN AHSNCKEGCV 2500
CQPGYVLRND KCVLRIECGC QHTQGGFIPA GKNWTSRGCS QSCDCMEGVI 2550
RCQNFQCPSG TYCQDIEDGT SNCANITLQC PAHSSFTNCL PPCQPSCSDP 2600
EGHCGGSTTK APSACQEGCV CEPDYVVLNN KCVPRIECGC KDAQGVLIPA 2650
DKIWINKGCT QTCACVTGTI HCRDFQCPSG TYCKDIKDDA SNCTEIILQC 2700
PDHSLYTHCL PSCLLSCSDP DGLCRGTSPE APSTCKEGCV CDPDYVLSND 2750
KCVLRIECGC KDAQGVLIPA GKTWINRGCT QSCSCMGGAI QCQNFKCPSE 2800
AYCQDMEDGN SNCTSIPLQC PAHSHYTNCL PTCQPSCSDP DGHCEGSSTK 2850
APSACKEGCV CEPDYVMLNN KCVPRIECGC KDTQGVLIPA DKTWINRGCT 2900
QSCTCRGGAI QCQKYHCSSG TYCKDMEDDS SSCATITLQC PAHSHFTNCL 2950
PPCQPSCLDS EGHCEGSTTK APSACQEGCV CEPDYVVLNN KCVPRIECGC 3000
KDAQGVLIPA DKTWINRGCT QSCTCKGGAI QCQKFQCPSE TYCKDIEDGN 3050
SNCTRISLQC PANSNFTSCL PSCQPSCSNT DVHCEGSSPN TLSSCREGCV 3100
CQSGYVLHND KCILRNQCGC KDAQGALIPE GKTWITSGCT QSCNCTGGAI 3150
QCQNFQCPLK TYCKDLKDGS SNCTNIPLQC PAHSRYTNCL PSCPPLCLDP 3200
EGLCEGTSPK VPSTCREGCI CQPGYLMHKN KCVLRIFCGC KNTQGAFISA 3250
DKTWISRGCT QSCTCPAGAI HCRNFKCPSG TYCKNGDNGS SNCTEITLQC 3300
PTNSQFTDCL PSCVPSCSNR CEVTSPSVPS SCREGCLCNH GFVFSEDKCV 3350
PRTQCGCKDA RGAIIPAGKT WTSKGCTQSC ACVEGNIQCQ NFQCPPETYC 3400
KDNSEGSSTC TKITLQCPAH TQYTSCLPSC LPSCLDPEGL CKDISPKVPS 3450
TCKEGCVCQS GYVLNSDKCV LRAECDCKDA QGALIPAGKT WTSPGCTQSC 3500
ACMGGAVQCQ SSQCPPGTYC KDNEDGNSNC AKITLQCPAH SLFTNCLPPC 3550
LPSCLDPDGL CKGASPKVPS TCKEGCICQS GYVLSNNKCL LRNRCGCKDA 3600
HGALIPEDKT WVSRGCTQSC VCTGGSIQCL SSQCPPGAYC KDNEDGSSNC 3650
ARIPPQCPAN SHYTDCFPPC PPSCSDPEGH CEASGPRVLS TCREGCLCNP 3700
GFVLDRDKCV PRVECGCKDA QGALIPSGKT WTSPGCTQSC ACMGGVVQCQ 3750
SSQCPPGTYC KDNEDGNSNC AKITLQCPTH SNYTDCLPFC LPSCLDPSAL 3800
CGGTSPKGPS TCKEGCVCQP GYVLDKDKCI LKIECGCRDT QGAVIPAGKT 3850
WLSTGCIQSC ACVEGTIQCQ NFQCPPGTYC NHNNNCAKIP LQCPAHSHFT 3900
SCLPSCPPSC ANLDGSCEQT SPKVPSTCKE GCLCQPGYFL NNGKCVLQTH 3950
CDCKDAEGGL VPAGKTWTSK DCTQSCACTG GAVQCQNFQC PLGTYCKDSG 4000
DGSSNCTKIH KGAMGDGVLM AGGIRALQCP AHSHFTSCLP SCPPSCSNLD 4050
GSCVESNFKA PSVCKKGCIC QPGYLLNNDK CVLRIQCGCK DTQGGLIPAG 4100
RTWISSDCTK SCSCMGGIIQ CRDFQCPPGT YCKESNDSSR TCAKIPLQCP 4150
AHSHYTNCLP ACSRSCTDLD GHCEGTSPKV PSPCKEGCLC QPGYVVHNHK 4200
CVLQIHCGCK DAQGGFVPAG KTWISRGCTQ SCACVGGAVQ CHNFTCPTGT 4250
QCQNSSCSKI TVQCPAHSQY TTCLPSCLPS CFDPEGLCGG ASPRAPSTCR 4300
EGCVCEADYV LREDKCVLRT QCGCKDAQGD LIPANKTWLT RGCAQKCTCK 4350
GGNIHCWNFK CPLGTECKDS VDGGSNCTKI ALQCPAHSHH TYCLPSCIPS 4400
CSNVNDRCES TSLQRPSTCI EGCLCHSGFV FSKDKCVPRT QCGCKDSQGT 4450
LIPAGKNWIT TGCSQRCTCT GGLVQCHDFQ CPSGAECQDI EDGNSNCVEI 4500
TVQCPAHSHY SKCLPPCQPS CSDPDGHCEG TSPEAPSTCE EGCVCEPDYV 4550
LSNDKCVPSS ECGCKDAHGV LIPESKTWVS RGCTKNCTCK GGTVQCHDFS 4600
CPTGSRCLDN NEGNSNCVTY ALKCPAHSLY TNCLPSCLPS CSDPEGLCGG 4650
TSPEVPSTCK EGCICQSGYV LHKNKCMLRI HCDCKDFQGS LIKTGQTWIS 4700
SGCSKICTCK GGFFQCQSYK CPSGTQCEES EDGSSNCVSS TMKCPANSLY 4750
THCLPTCLPS CSNPDGRCEG TSHKAPSTCR EGCVCQPGYL LNKDTCVHKN 4800
QCGCKDIRGN IIPAGNTWIS SDCTQSCACT DGVIQCQNFV CPSGSHCQYN 4850
EDGSSDCAAN KLERCTIFGD PYYLTFDGFT YHFLGRMNYY LIKTVDKLPR 4900
GIEPLIMEGR NKISPKGSST LHEVTTIVYG YKIQLQEELV VLVNDEKVAV 4950
PYNPNEHLRV MLRAQRLLLV TDFEMVLDFD GKHSAVISLP TTYRGLTRGL 5000
CGNYDRDQSN ELMLPSGVLT SNVHVFGNSW EVKAQHAFFR FPRALPEDEE 5050
RDEEPDLLQS ECSQEQTALI SSTQACRVLV DPQGPFAACH QIIAPEPFEQ 5100
RCMLDMCTGW KTKEEEELRC RVLSGYAIIC QEAGANMTGW RDHTHCAMTC 5150
PANTVYQRCM TPCPASCAKF VTPKVCEGPC VEGCASLPGY IYSDTQSLPV 5200
THCGCTADGI YYKLGDSFVT NDCSQHCTCA SQGILLCEPY GCRAGESCMV 5250
ANFTRGCFQD SPCLQNPCHN DGRCEEQGAT FICHCDFGYG GEFCTEPQDI 5300
TTRKKIEASS LVAILPGVLV MVLVPVLLPR VYVYMATRTT MGRRRMKRKE 5350
KKLLRQSRLR LEDADVPEPT FKATEF 5376
Length:5,376
Mass (Da):579,913
Last modified:November 1, 1998 - v1
Checksum:i0E44DB77DF2A2620
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U97068 mRNA. Translation: AAC26680.1.
U83190 mRNA. Translation: AAC53125.1.
PIRiT42215.
UniGeneiMm.7984.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U97068 mRNA. Translation: AAC26680.1 .
U83190 mRNA. Translation: AAC53125.1 .
PIRi T42215.
UniGenei Mm.7984.

3D structure databases

ProteinModelPortali O88799.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei O88799.

Proteomic databases

PaxDbi O88799.
PRIDEi O88799.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:106656. Zan.

Phylogenomic databases

eggNOGi NOG12793.
HOVERGENi HBG003977.
PhylomeDBi O88799.

Miscellaneous databases

PROi O88799.
SOURCEi Search...

Gene expression databases

CleanExi MM_ZAN.
Genevestigatori O88799.

Family and domain databases

InterProi IPR008985. ConA-like_lec_gl_sf.
IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR003645. Fol_N.
IPR000998. MAM_dom.
IPR002919. TIL_dom.
IPR025615. TILa_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR001007. VWF_C.
IPR001846. VWF_type-D.
[Graphical view ]
Pfami PF00629. MAM. 3 hits.
PF01826. TIL. 25 hits.
PF12714. TILa. 25 hits.
PF00094. VWD. 4 hits.
[Graphical view ]
SMARTi SM00832. C8. 4 hits.
SM00181. EGF. 2 hits.
SM00274. FOLN. 20 hits.
SM00137. MAM. 3 hits.
SM00214. VWC. 17 hits.
SM00216. VWD. 4 hits.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 3 hits.
SSF57567. SSF57567. 25 hits.
PROSITEi PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 18 hits.
PS50026. EGF_3. 1 hit.
PS00740. MAM_1. 1 hit.
PS50060. MAM_2. 3 hits.
PS51233. VWFD. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Species diversity in the structure of zonadhesin, a sperm-specific membrane protein containing multiple cell adhesion molecule-like domains."
    Gao Z., Garbers D.L.
    J. Biol. Chem. 273:3415-3421(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Testis.
  2. "Chromosome localization of the mouse zonadhesin gene and the human zonadhesin gene (ZAN)."
    Gao Z., Harumi T., Garbers D.L.
    Genomics 41:119-122(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4864-5376.
    Tissue: Testis.

Entry informationi

Entry nameiZAN_MOUSE
AccessioniPrimary (citable) accession number: O88799
Secondary accession number(s): O08647
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: November 1, 1998
Last modified: April 16, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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