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Protein
Submitted name:

ArfGAP with dual PH domains 1

Gene

Adap1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • inositol phosphate-mediated signaling Source: RGD
  • regulation of GTPase activity Source: RGD

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
ArfGAP with dual PH domains 1Imported
Submitted name:
IP4/PIP3 binding proteinImported
Gene namesi
Name:Adap1Imported
Synonyms:Centa1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi621418 Adap1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000054033

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001736

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 126Arf-GAPInterPro annotationAdd BLAST121
Domaini129 – 230PHInterPro annotationAdd BLAST102
Domaini252 – 356PHInterPro annotationAdd BLAST105

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0703 Eukaryota
COG5347 LUCA
GeneTreeiENSGT00900000140892
HOVERGENiHBG050888
TreeFamiTF324540

Family and domain databases

CDDicd13252 PH1_ADAP, 1 hit
cd01251 PH2_ADAP, 1 hit
Gene3Di2.30.29.30, 2 hits
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR011993 PH-like_dom_sf
IPR037849 PH1_ADAP
IPR037851 PH2_ADAP
IPR001849 PH_domain
PfamiView protein in Pfam
PF01412 ArfGap, 1 hit
PF00169 PH, 2 hits
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00105 ArfGap, 1 hit
SM00233 PH, 2 hits
SUPFAMiSSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50115 ARFGAP, 1 hit
PS50003 PH_DOMAIN, 2 hits

Sequencei

Sequence statusi: Complete.

O88768-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGERRRALL ELLTRPGNSR CADCGAPDPD WASYTLGVFI CLSCSGIHRN
60 70 80 90 100
IPQVSKVKSV RLDAWDETQV EFMTSHGNEA ARATFESKVP PFYYRPTFSD
110 120 130 140 150
CQLLREQWIR AKYERQEFLH VEKQEPYSTG YREGLLWKRG RDNGQFLSRK
160 170 180 190 200
FVLTEREGAL KYFNKNDAKE PKAVMKIEHL NATFQPAKIG HPHGLQVTYL
210 220 230 240 250
KDNSTRNIFI YHEDGKEIVD WFNALRAARF HYLQVAFPGA SDADLVPKLS
260 270 280 290 300
RNYLKEGYME KTGPKQTEGF RKRWFTMDDR RLMYFKDPLD AFARGEVFIG
310 320 330 340 350
SKESGYTVLE GLPPSTQSHH WPHGITIVTP DRKFLFTCET ESDQREWIAA
360 370
FQKVVDRPML PQEYAVEAHF KHKP
Length:374
Mass (Da):43,426
Last modified:November 1, 1998 - v1
Checksum:i8EA0A0300BC3078E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127903 Genomic DNA No translation available.
BC099775 mRNA Translation: AAH99775.1
AJ007422 mRNA Translation: CAA07496.1
RefSeqiNP_598251.1, NM_133567.2
UniGeneiRn.10539

Genome annotation databases

EnsembliENSRNOT00000089590; ENSRNOP00000075236; ENSRNOG00000054033
GeneIDi171097
KEGGirno:171097

Similar proteinsi

Entry informationi

Entry nameiO88768_RAT
AccessioniPrimary (citable) accession number: O88768
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health