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Protein
Submitted name:

Epsilon 3 globin

Gene

Hbg1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi64Iron (heme distal ligand)PROSITE-ProRule annotation1
Metal bindingi93Iron (heme proximal ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

  • heme binding Source: RGD
  • hemoglobin alpha binding Source: RGD
  • iron ion binding Source: InterPro
  • oxygen binding Source: InterPro
  • oxygen transporter activity Source: UniProtKB-KW

GO - Biological processi

  • protein heterooligomerization Source: RGD

Keywordsi

Biological processOxygen transportPROSITE-ProRule annotationSAAS annotation, Transport
LigandHemePROSITE-ProRule annotationSAAS annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-RNO-983231. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Submitted name:
Epsilon 3 globinImported
Submitted name:
Globin b2Imported
Submitted name:
Hemoglobin subunit gamma 1Imported
Submitted name:
Hemoglobin, gamma AImported
Submitted name:
RCG39434, isoform CRA_aImported
Gene namesi
Name:Hbg1Imported
Synonyms:epsilon 3Imported, Glnb2Imported
ORF Names:rCG_39434Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi620306. Hbg1.

Subcellular locationi

GO - Cellular componenti

  • hemoglobin complex Source: RGD

Interactioni

GO - Molecular functioni

  • hemoglobin alpha binding Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000043418.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 147GLOBINInterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
GeneTreeiENSGT00760000119197.
HOGENOMiHOG000036868.
HOVERGENiHBG009709.
KOiK13825.
OMAiRIRAHGK.
OrthoDBiEOG091G0R7W.
TreeFamiTF333268.

Family and domain databases

CDDicd08925. Hb-beta_like. 1 hit.
InterProiView protein in InterPro
IPR000971. Globin.
IPR009050. Globin-like.
IPR002337. Haemoglobin_b.
PfamiView protein in Pfam
PF00042. Globin. 1 hit.
PRINTSiPR00814. BETAHAEM.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiView protein in PROSITE
PS01033. GLOBIN. 1 hit.

Sequencei

Sequence statusi: Complete.

O88754-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHFTAEEKA AIISIWEKVD LEKIGGETLG RLLIVYPWTQ RFFDKFGNLS
60 70 80 90 100
SALAIMGNPR IRAHGKKVLT SLGSAVENMD NLKETFAHLS ELHCDKLHVD
110 120 130 140
PQNFKLLGNM LVIVLSTHFA KEFTPEVQAA WQKLVMGVAN ALSHKYH
Length:147
Mass (Da):16,540
Last modified:November 1, 1998 - v1
Checksum:i39BF594C21B3DC1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113925 Genomic DNA. No translation available.
BC157810 mRNA. Translation: AAI57811.1.
X56328 Genomic DNA. Translation: CAA39767.1.
CH473956 Genomic DNA. Translation: EDM18108.1.
LT548166 Genomic DNA. Translation: SAI82213.1.
RefSeqiNP_742090.1. NM_172093.1.
UniGeneiRn.203045.

Genome annotation databases

EnsembliENSRNOT00000039946; ENSRNOP00000043418; ENSRNOG00000030879.
GeneIDi94164.
KEGGirno:94164.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO88754_RAT
AccessioniPrimary (citable) accession number: O88754
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: July 5, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported