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Protein
Submitted name:

Epsilon 3 globin

Gene

Hbg1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi64Iron (heme distal ligand)PROSITE-ProRule annotation1
Metal bindingi93Iron (heme proximal ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

  • heme binding Source: RGD
  • hemoglobin alpha binding Source: RGD
  • metal ion binding Source: UniProtKB-KW
  • oxygen binding Source: InterPro
  • oxygen carrier activity Source: UniProtKB-KW

GO - Biological processi

Keywordsi

Biological processOxygen transportPROSITE-ProRule annotationSAAS annotation, Transport
LigandHemePROSITE-ProRule annotationSAAS annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-RNO-983231 Factors involved in megakaryocyte development and platelet production

Names & Taxonomyi

Protein namesi
Submitted name:
Epsilon 3 globinImported
Submitted name:
Globin b2Imported
Submitted name:
Hemoglobin subunit gamma 1Imported
Submitted name:
Hemoglobin, gamma AImported
Submitted name:
RCG39434, isoform CRA_aImported
Gene namesi
Name:Hbg1Imported
Synonyms:epsilon 3Imported, Glnb2Imported
ORF Names:rCG_39434Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi620306 Hbg1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000030879

Interactioni

GO - Molecular functioni

  • hemoglobin alpha binding Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000043418

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 147GLOBINInterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3378 Eukaryota
COG1018 LUCA
GeneTreeiENSGT00760000119197
HOGENOMiHOG000036868
HOVERGENiHBG009709
KOiK13825
OMAiRIRAHGK
OrthoDBiEOG091G0R7W
TreeFamiTF333268

Family and domain databases

CDDicd08925 Hb-beta_like, 1 hit
Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002337 Haemoglobin_b
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00814 BETAHAEM
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

O88754-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHFTAEEKA AIISIWEKVD LEKIGGETLG RLLIVYPWTQ RFFDKFGNLS
60 70 80 90 100
SALAIMGNPR IRAHGKKVLT SLGSAVENMD NLKETFAHLS ELHCDKLHVD
110 120 130 140
PQNFKLLGNM LVIVLSTHFA KEFTPEVQAA WQKLVMGVAN ALSHKYH
Length:147
Mass (Da):16,540
Last modified:November 1, 1998 - v1
Checksum:i39BF594C21B3DC1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113925 Genomic DNA No translation available.
BC157810 mRNA Translation: AAI57811.1
X56328 Genomic DNA Translation: CAA39767.1
CH473956 Genomic DNA Translation: EDM18108.1
LT548166 Genomic DNA Translation: SAI82213.1
RefSeqiNP_742090.1, NM_172093.1
UniGeneiRn.203045

Genome annotation databases

EnsembliENSRNOT00000039946; ENSRNOP00000043418; ENSRNOG00000030879
GeneIDi94164
KEGGirno:94164

Similar proteinsi

Entry informationi

Entry nameiO88754_RAT
AccessioniPrimary (citable) accession number: O88754
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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