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O88737 (BSN_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified September 21, 2011. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein bassoon
Gene names
Name:Bsn
Synonyms:Kiaa0434
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length3942 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses By similarity. Involved in the formation of the retinal photoreceptor ribbon synapses. Ref.4 Ref.5

Subunit structure

Interacts with ERC2/CAST1, RIMS1 and UNC13A. Part of a complex consisting of ERC2, RIMS1 and BSN By similarity.

Subcellular location

Cytoplasm. Cell junction › synapse › synaptosome. Cytoplasm › cytoskeleton. Note: Localized to the active zone of presynaptic density. Ref.4 Ref.5

Tissue specificity

Expressed in brain and retina. Ref.4 Ref.5

Post-translational modification

Myristoylated. The N-terminal myristoylation is not sufficient for presynaptic localization By similarity.

Disruption phenotype

Mice show a reduced excitability attributed to inactivation of a fraction of brain glutamatergic synapses. At these synapses, vesicles are clustered and docked in normal numbers, but were unable to fuse. In retina, mutants lacking functional BSN showed normal retinal anatomy, but synapses lacked anchoring of the photoreceptor ribbon to the presynaptic active zone resulting in impaired photoreceptor synaptic transmission. Ref.4

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: O88737-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: O88737-2)

The sequence of this isoform differs from the canonical sequence as follows:
     2833-2889: Missing.
Note: Incompl.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 39423941Protein bassoon
PRO_0000065003

Regions

Repeat570 – 57671
Repeat577 – 58372
Repeat584 – 59073
Repeat591 – 59774
Repeat598 – 60475
Zinc finger167 – 19024C4-type Potential
Zinc finger195 – 21723C4-type Potential
Zinc finger464 – 48724C4-type Potential
Zinc finger492 – 51423C4-type Potential
Region62 – 71105 X 2 AA tandem repeats of P-G
Region570 – 604355 X 7 AA tandem repeats of K-A-S-P-Q-[AT]-[AT]
Compositional bias2608 – 26147Poly-Arg
Compositional bias2635 – 26406Poly-Arg
Compositional bias3784 – 379815Poly-Gln

Amino acid modifications

Modified residue61Phosphoserine Ref.6
Modified residue1051Phosphoserine Ref.11
Modified residue1351Phosphoserine By similarity
Modified residue1401Phosphoserine By similarity
Modified residue1421Phosphoserine Ref.11
Modified residue9801Phosphoserine Ref.11
Modified residue10191Phosphoserine Ref.7
Modified residue11021Phosphothreonine Ref.6
Modified residue11051Phosphoserine Ref.6
Modified residue11081Phosphoserine Ref.6 Ref.7
Modified residue11141Phosphoserine Ref.6 Ref.7
Modified residue11161Phosphothreonine Ref.11
Modified residue11361Phosphotyrosine Ref.11
Modified residue12361Phosphoserine Ref.7
Modified residue14061Phosphothreonine Ref.11
Modified residue14811Phosphoserine Ref.6
Modified residue14821Phosphoserine Ref.6 Ref.11
Modified residue14861Phosphoserine Ref.6
Modified residue14931Phosphoserine Ref.6
Modified residue14951Phosphothreonine Ref.6
Modified residue14971Phosphoserine Ref.6
Modified residue15101Phosphoserine Ref.6
Modified residue15531Phosphoserine Ref.6
Modified residue15541Phosphoserine Ref.6
Modified residue20291Phosphoserine Ref.6
Modified residue20441Phosphotyrosine Ref.11
Modified residue20731Phosphotyrosine Ref.9
Modified residue21221Phosphoserine Ref.6
Modified residue21241Phosphoserine Ref.6
Modified residue25781Phosphoserine Ref.7
Modified residue25951Phosphothreonine Ref.7 Ref.11
Modified residue26221Phosphothreonine Ref.7
Modified residue26941Phosphoserine Ref.10
Modified residue27031Phosphothreonine Ref.10
Modified residue28081Phosphoserine Ref.6
Modified residue28111Phosphoserine Ref.6 Ref.11
Modified residue28221Phosphoserine Ref.6
Modified residue28581Phosphoserine Ref.6 Ref.11
Modified residue28601Phosphoserine Ref.6 Ref.7 Ref.11
Modified residue28661Phosphoserine Ref.6 Ref.7 Ref.11
Modified residue29081Phosphoserine Ref.6 Ref.11
Modified residue30221Phosphoserine Ref.11
Modified residue33011Phosphoserine Ref.7 Ref.11
Modified residue33821Phosphoserine Ref.7 Ref.11
Modified residue34311Phosphotyrosine Ref.10
Modified residue34321Phosphotyrosine Ref.10
Modified residue34591Phosphotyrosine Ref.11
Lipidation21N-myristoyl glycine By similarity
Glycosylation13541O-linked (GlcNAc) By similarity
Glycosylation13951O-linked (GlcNAc) Ref.8
Glycosylation17071O-linked (GlcNAc) Ref.8
Glycosylation19341O-linked (GlcNAc) Ref.8
Glycosylation23181O-linked (GlcNAc) Ref.8
Glycosylation25241O-linked (GlcNAc) Ref.8
Glycosylation27001O-linked (GlcNAc) Ref.8
Glycosylation29451O-linked (GlcNAc) Ref.8

Natural variations

Alternative sequence2833 – 288957Missing in isoform 2.
VSP_011375

Experimental info

Sequence conflict3811Q → P in CAA76598. Ref.1
Sequence conflict4181M → T in CAA76598. Ref.1
Sequence conflict4621S → A in CAA76598. Ref.1
Sequence conflict4731M → V in CAA76598. Ref.1
Sequence conflict624 – 6263VTS → ATP in CAA76598. Ref.1
Sequence conflict7831T → M in CAA76598. Ref.1
Sequence conflict22921A → T in CAA76598. Ref.1
Sequence conflict23491V → A in CAA76598. Ref.1
Sequence conflict28921A → V in CAA76598. Ref.1
Sequence conflict39021S → G in CAA76598. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified July 27, 2011. Version 4.
Checksum: E8BEE60189570857

FASTA3,942418,843
        10         20         30         40         50         60 
MGNEASLEGG AGEGPLPPGG SGLGPGPGAG KPPSALAGGG QLPVAGAARA AGPPTPGLGP 

        70         80         90        100        110        120 
VPGPGPGPGP GSVPRRLDPK EPLGSQRTTS PTPKQASATA PGRESPRETR AQGPSGQEAE 

       130        140        150        160        170        180 
SPRRTLQVDS RTQRSGRSPS VSPDRGSTPT SPYSVPQIAP LPSSTLCPIC KTSDLTSTPS 

       190        200        210        220        230        240 
QPNFNTCTQC HNKVCNQCGF NPNPHLTQVK EWLCLNCQMQ RALGMDMTTA PRSKSQQQLH 

       250        260        270        280        290        300 
SPALSPAHSP AKQPLGKPEQ ERSPRGPGAT QSGPRQAEAA RATSVPGPTQ ATAPPEVGRV 

       310        320        330        340        350        360 
SPQPPLSTKP STAEPRPPAG EAQGKSATTV PSGLGAGEQT QEGLTGKLFG LGASLLTQAS 

       370        380        390        400        410        420 
TLMSVQPEAD TQGQPSPSKG QPKIVFSDAS KEAGPRPPGS GPGPGPTPGA KTEPGARMGP 

       430        440        450        460        470        480 
GSGPGALAKT GGTASPKHGR AEHQAASKAA AKPKTMPKER ASACPLCQAE LNMGSRGPAN 

       490        500        510        520        530        540 
YNTCTACKLQ VCNLCGFNPT PHLVEKTEWL CLNCQTKRLL EGSLGEPAPL PLPTPQQPPA 

       550        560        570        580        590        600 
GVPHRAAGAA PLKQKGPQGL GQPSGSLPAK ASPQATKASP QATKASPQAT KASPQTTKAS 

       610        620        630        640        650        660 
PQAKPLRATE PSKTSSSAQE KKTVTSAKAE PVPKPPPETT VPPGTPKAKS GVKRTDPATP 

       670        680        690        700        710        720 
VVKPVPEAPK GGEAEEPVPK PYSQDLSRSP QSLSDTGYSS DGVSSSQSEI TGVVQQEVEQ 

       730        740        750        760        770        780 
LDSAGVTGPR PPSPSELHKV GSSLRPSLEA QAVAPSAEWS KPPRSSSSAV EDQKRRPHSL 

       790        800        810        820        830        840 
SITPEAFDSD EELGDILEED DSLAWGRQRE QQDTAESSDD FGSQLRHDYV EDSSEGGLSP 

       850        860        870        880        890        900 
LPPQPPARAD MTDEEFMRRQ ILEMSAEEDN LEEDDTAVSG RGLAKHSAQK ASARPRPESS 

       910        920        930        940        950        960 
QEPKRRLPHN ATTGYEELLS EAGPAEPTDS SGALQGGLRR FKTIELNSTG SYGHELDLGQ 

       970        980        990       1000       1010       1020 
GPDPNLDREP ELEMESLTGS PEDRSRGEHS STLPASTPSY TSGTSPTSLS SLEEDSDSSP 

      1030       1040       1050       1060       1070       1080 
SRRQRLEEAK QQRKARHRSH GPLLPTIEDS SEEEELREEE ELLREQEKMR EVEQQRIRST 

      1090       1100       1110       1120       1130       1140 
ARKTRRDKEE LRAQRRRERS KTPPSNLSPI EDASPTEELR QAAEMEELHR SSCSEYSPSP 

      1150       1160       1170       1180       1190       1200 
SLDSEAETLD GGPTRLYKSG SEYNLPAFMS LYSPTETPSG SSTTPSSGRP LKSAEEAYED 

      1210       1220       1230       1240       1250       1260 
MMRKAEMLQR QQGQVAGARG PHGGPSQPTG PRSQGSFEYQ DTQDHDYGGR ASQPVAESTP 

      1270       1280       1290       1300       1310       1320 
AGLGAAVYEE ILQTSQSIAR MRQASSRDLG FTEDKKKEKQ FLNAESAYMD PMKQNGGPLT 

      1330       1340       1350       1360       1370       1380 
PGTSPTQLAA PVSFSTSTSS DSSGGRVIPD VRVTQHFAKE PQDPLKLHSS PVSSTLTSKE 

      1390       1400       1410       1420       1430       1440 
VGMTFSQGPG SPATTASPTR GYMTPTSPAG SERSPSTSST IHSYGQPPTT ANYGSQTEEL 

      1450       1460       1470       1480       1490       1500 
PHAPSGPPGS GRAPREKPLS GGDSEVGAPQ PSRGYSYFTG SSPPLSPSTP SESPTFSPGK 

      1510       1520       1530       1540       1550       1560 
LGPRATAEFS TQTPSLTLSS DIPRSPGPPS PMVAQGTQTP HRPSTPRLVW QQSSQEAPIM 

      1570       1580       1590       1600       1610       1620 
VITLASDASS QTRMVHASAS TSPLCSPTDS QPTSHSYSQT TPPSASQMPS EPAGPPGFPR 

      1630       1640       1650       1660       1670       1680 
APSAGTDGPL ALYGWGALPA ENISLCRISS VPGTSRVEPG PRPPGTAVVD LRTAVKPTPI 

      1690       1700       1710       1720       1730       1740 
ILTDQGMDLT SLAVEARKYG LALDPVSGRQ STAVQPLVIN LNAQEQTHTF LATATTVSIT 

      1750       1760       1770       1780       1790       1800 
MASSVLMAQQ KQPVVYGDPF QSRLDFGQGS GSPVCLAQVK QVEQAVQTAP YRGGPRGRPR 

      1810       1820       1830       1840       1850       1860 
EAKFARYNLP NQVTPLARRD ILITQMGTAQ GVGLKPGPVP EPGAEPHRAT PAELRSHAPP 

      1870       1880       1890       1900       1910       1920 
GTRKPHTVVV QMGEGTAGTV TTLLPEEPAG ALDLTGMRPE SQLACCDMVY KFPFGSSCTG 

      1930       1940       1950       1960       1970       1980 
TFHPAPSAPD KSVTDTALPG QSSGPFYSPR DPEPPEPLTF RTQGVVGPGP HEEQRPYPQG 

      1990       2000       2010       2020       2030       2040 
LPGRLYSSMS DTNLAEAGLN YHAQRLGQLF QGPGRDSAVD LSSLKHSYSL GFADGRYLGQ 

      2050       2060       2070       2080       2090       2100 
GLQYGSFTDL RHPTDLLSHP LPLRRYSSVS NIYSDHRYGP RGDAVGFQEA SLAQYSATTA 

      2110       2120       2130       2140       2150       2160 
REISRMCAAL NSMDQYGGRH GSGSGGPDLV QYQPQHGPGL SAPQGLAPLR SGLLGNPTYP 

      2170       2180       2190       2200       2210       2220 
EGQPSPGNLA QYGPAASQAT AVRQLLPSTA TVRAADGMIY STINTPIAAT LPITTQPASV 

      2230       2240       2250       2260       2270       2280 
LRPMVRGGMY RPYVSGGVTA VPLTSLTRVP MIAPRVPLGP AGLYRYPAPR FPIASSVPPA 

      2290       2300       2310       2320       2330       2340 
EGPVYLGKPA AAKASGAGGP PRPELPAGVA REEPFSTTAP AVIKEAPVAP APGPAPAPPP 

      2350       2360       2370       2380       2390       2400 
GQKPAGEAVA GSGSGVLSRP ASEKEEASQE DRQRKQQEQL LQLERERVEL EKLRQLRLQE 

      2410       2420       2430       2440       2450       2460 
ELERERVELQ RHREEEQLLV QRELQELQTI KQHVLQQQQE ERQAQFALQR EQLAQQRLQL 

      2470       2480       2490       2500       2510       2520 
EQIQQLQQQL QLQLEEQKQR QKAPFPATCE APSRGPPPAA TELAQNGQYW PPLTHAAFIA 

      2530       2540       2550       2560       2570       2580 
VAGTEGPGQP REPVLHRGLP SSASDMSLQT EEQWEAGRSG IKKRHSMPRL RDACEPESGP 

      2590       2600       2610       2620       2630       2640 
DPSTVRRIAD SSVQTDDEEG EGRYLVTRRR RTRRSADCSV QTDDEDNADW EQPVRRRRSR 

      2650       2660       2670       2680       2690       2700 
LSRHSDSGSD SKHDATASSS TTAAATARAM SSVGIQTISD CSVQTEPEQL PRVSPAIHIT 

      2710       2720       2730       2740       2750       2760 
AATDPKVEIV RYISAPEKTG RGESLACQTE PDGQAQGVAG PQLIGPTAIS PYLPGIQIVT 

      2770       2780       2790       2800       2810       2820 
PGALGRFEKK KPDPLEIGYQ AHLPPESLSQ LVSRQPPKSP QVLYSPVSPL SPHRLLDTSF 

      2830       2840       2850       2860       2870       2880 
ASSERLNKAH VSPQKQFIAD STLRQQTLPR PMKTLQRSLS DPKPLSPTAE ESAKERFSLY 

      2890       2900       2910       2920       2930       2940 
QHQGGLGSQV SALPPNGLVR KVKRTLPSPP PEEAHLPLAG QVPSQLYAAS LLQRGLAGPT 

      2950       2960       2970       2980       2990       3000 
TVPATKASLL RELDRDLRLV EHESTKLRKK QAELDEEEKE IDAKLKYLEL GITQRKESLA 

      3010       3020       3030       3040       3050       3060 
KDRGGRDYPP LRGLGEHRDY LSDSELNQLR LQGCTTPAGQ YVDYPASAAV PATPSGPTAF 

      3070       3080       3090       3100       3110       3120 
QQPRFPPAAP QYTAGSSGPT QNGFPAHQAP TYTGPSTYPA PTYPPGTGYP AEPGLPSQPA 

      3130       3140       3150       3160       3170       3180 
FHPTGHYAAP TPMPTTQSAP FPVQADSRAA HQKPRQTSLA DLEQKVPTNY EVIGSPAVTM 

      3190       3200       3210       3220       3230       3240 
SSAPPETGYS GPAVSGSYEQ GKAPEHPRGS DRSSVSQSPA PTYPSDSHYT SLEQNVPRNY 

      3250       3260       3270       3280       3290       3300 
VMIDDISELT KDSTPTASES QRLEPLGPGG VSGRPGKDPG EPAVLEGPTL PCCYGRGEEE 

      3310       3320       3330       3340       3350       3360 
SEEDSYDPRG KSGHHRSMES NGRPSTHYYG DSDYRHGARA DKYGPGPMGP KHPSKSLAPA 

      3370       3380       3390       3400       3410       3420 
AISSKRSKHR KQGMEQKISK FSPIEEAKDV ESDLASYPPP TVSSSLTSRG RKFQDEITYG 

      3430       3440       3450       3460       3470       3480 
LKKNVYEQQR YYGVSSRDAA EEDERMYGSS SRSRMASAYS GEKLSSHDYS SRGKGYERER 

      3490       3500       3510       3520       3530       3540 
DTAERLQKAG SKPSSLSMAH GRARPPMRSQ ASEEESPVSP LGRPRPAGGA LPPGDTCPQF 

      3550       3560       3570       3580       3590       3600 
CSSHSMPDVQ EHVKDGPRAH AYKREEGYML DDSHCVVSDS EAYHLGQEET DWFDKPRDAR 

      3610       3620       3630       3640       3650       3660 
SDRFRHHGGH TVSSSQKRGP ARHSYHDYDE PPEEGLWPHD EGGPGRHTSA KEHRHHSDHG 

      3670       3680       3690       3700       3710       3720 
RHSGRHAGEE PGRRAAKPHA RDMGRHEARP HPQASPAPAM QKKGQPGYPS SADYSQSSRA 

      3730       3740       3750       3760       3770       3780 
PSAYHHASES KKGSRQAHTG PSALQPKADT QAQPQMQGRQ AAPGPQQSQP PSSRQTPSGT 

      3790       3800       3810       3820       3830       3840 
ASRQPQTQQQ QQQQQQQQGL GQQAPQQAPS QARLQPQSQP TTRGTAPAAS QPAGKPQPGP 

      3850       3860       3870       3880       3890       3900 
TTAPGPQPAG PPRAEQASSS KPPAAKAPQQ GRAPQAQTTP GPGPAGAKPG ARPGGTPGAP 

      3910       3920       3930       3940 
ASQPGAEGES VFSKILPGGA AEQAGKLTEA VSAFGKKFSS FW

« Hide

Isoform 2 [UniParc].

Checksum: FA881C3C47BE33F6
Show »

FASTA3,885412,451

References

« Hide 'large scale' references
[1]"Bassoon, a novel zinc-finger CAG/Glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals."
tom Dieck S., Sanmarti-Vila L., Langnaese K., Richter K., Kindler S., Soyke A., Wex H., Smalla K.-H., Kaempf U., Fraenzer J.-T., Stumm M., Garner C.C., Gundelfinger E.D.
J. Cell Biol. 142:499-509(1998) [PubMed: 9679147] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1).
Strain: 129/SvJ.
[2]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6.
[3]"Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
DNA Res. 10:167-180(2003) [PubMed: 14621295] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2714-3942 (ISOFORM 2).
Tissue: Brain.
[4]"The presynaptic active zone protein bassoon is essential for photoreceptor ribbon synapse formation in the retina."
Dick O., tom Dieck S., Altrock W.D., Ammermueller J., Weiler R., Garner C.C., Gundelfinger E.D., Brandstaetter J.H.
Neuron 37:775-786(2003) [PubMed: 12628168] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.
[5]"Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon."
Altrock W.D., tom Dieck S., Sokolov M., Meyer A.C., Sigler A., Brakebusch C., Faessler R., Richter K., Boeckers T.M., Potschka H., Brandt C., Loescher W., Grimberg D., Dresbach T., Hempelmann A., Hassan H., Balschun D., Frey J.U. expand/collapse author list , Brandstaetter J.H., Garner C.C., Rosenmund C., Gundelfinger E.D.
Neuron 37:787-800(2003) [PubMed: 12628169] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[6]"Proteomic analysis of in vivo phosphorylated synaptic proteins."
Collins M.O., Yu L., Coba M.P., Husi H., Campuzano I., Blackstock W.P., Choudhary J.S., Grant S.G.
J. Biol. Chem. 280:5972-5982(2005) [PubMed: 15572359] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-6; THR-1102; SER-1105; SER-1108; SER-1114; SER-1481; SER-1482; SER-1486; SER-1493; THR-1495; SER-1497; SER-1510; SER-1553; SER-1554; SER-2029; SER-2122; SER-2124; SER-2808; SER-2811; SER-2822; SER-2858; SER-2860; SER-2866 AND SER-2908, MASS SPECTROMETRY.
Tissue: Forebrain.
[7]"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
Mol. Cell. Proteomics 5:914-922(2006) [PubMed: 16452087] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1019; SER-1108; SER-1114; SER-1236; SER-2578; THR-2595; THR-2622; SER-2860; SER-2866; SER-3301 AND SER-3382, MASS SPECTROMETRY.
Tissue: Brain.
[8]"O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry."
Vosseller K., Trinidad J.C., Chalkley R.J., Specht C.G., Thalhammer A., Lynn A.J., Snedecor J.O., Guan S., Medzihradszky K.F., Maltby D.A., Schoepfer R., Burlingame A.L.
Mol. Cell. Proteomics 5:923-934(2006) [PubMed: 16452088] [Abstract]
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT THR-1395; SER-1707; THR-1934; THR-2318; THR-2524; THR-2700 AND THR-2945, MASS SPECTROMETRY.
Tissue: Brain.
[9]"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.
J. Proteome Res. 7:311-318(2008) [PubMed: 18034455] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-2073, MASS SPECTROMETRY.
Tissue: Brain.
[10]"Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry."
Dai J., Jin W.-H., Sheng Q.-H., Shieh C.-H., Wu J.-R., Zeng R.
J. Proteome Res. 6:250-262(2007) [PubMed: 17203969] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2694; THR-2703; TYR-3431 AND TYR-3432, MASS SPECTROMETRY.
Tissue: Liver.
[11]"Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F., Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D., Gerrits B., Panse C., Schlapbach R., Mansuy I.M.
Mol. Cell. Proteomics 6:283-293(2007) [PubMed: 17114649] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-105; SER-142; SER-980; THR-1116; TYR-1136; THR-1406; SER-1482; TYR-2044; THR-2595; SER-2811; SER-2858; SER-2860; SER-2866; SER-2908; SER-3022; SER-3301; SER-3382 AND TYR-3459, MASS SPECTROMETRY.
Tissue: Brain cortex.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Y17034 expand/collapse EMBL AC list , Y17035, Y17036, Y17037, Y17038 Genomic DNA. Translation: CAA76598.1.
AC137678 Genomic DNA. No translation available.
AC168217 Genomic DNA. No translation available.
AK129141 mRNA. Translation: BAC97951.1.
IPIIPI00134093.
IPI00461199.
PIRT42730.
RefSeqNP_031593.2. NM_007567.2.
UniGeneMm.20425.

3D structure databases

ProteinModelPortalO88737.
ModBaseSearch...

Protein-protein interaction databases

IntActO88737. 3 interactions.
MINTMINT-136785.
STRINGO88737.

PTM databases

PhosphoSiteO88737.

Proteomic databases

PRIDEO88737.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000035208; ENSMUSP00000035208; ENSMUSG00000032589.
GeneID12217.
KEGGmmu:12217.
UCSCuc009rov.1. mouse.

Organism-specific databases

CTD8927.
MGIMGI:1277955. Bsn.
RougeSearch...

Phylogenomic databases

eggNOGroNOG04262.
HOGENOMHBG447034.
HOVERGENHBG080934.
InParanoidO88737.
OrthoDBEOG4G4GPH.

Gene expression databases

ArrayExpressO88737.
BgeeO88737.
CleanExMM_BSN.
GenevestigatorO88737.
GermOnlineENSMUSG00000032589. Mus musculus.

Family and domain databases

InterProIPR011011. Znf_FYVE_PHD.
IPR008899. Znf_piccolo.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
Gene3DG3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 2 hits.
PfamPF05715. zf-piccolo. 2 hits.
[Graphical view]
SUPFAMSSF57903. FYVE_PHD_ZnF. 2 hits.
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameBSN_MOUSE
AccessionPrimary (citable) accession number: O88737
Secondary accession number(s): E9QMZ3, Q6ZQB5
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: July 27, 2011
Last modified: September 21, 2011
This is version 87 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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