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Protein
Submitted name:

Zinc finger protein 54

Gene

Zfp54

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein 54Imported
Gene namesi
Name:Zfp54Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99201. Zfp54.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO88631.

Interactioni

Protein-protein interaction databases

IntActiO88631. 1 interaction.
MINTiMINT-1577357.
STRINGi10090.ENSMUSP00000007884.

Structurei

3D structure databases

ProteinModelPortaliO88631.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini92 – 17483KRABInterPro annotationAdd
BLAST
Domaini262 – 28928C2H2-typeInterPro annotationAdd
BLAST
Domaini290 – 31728C2H2-typeInterPro annotationAdd
BLAST
Domaini322 – 34928C2H2-typeInterPro annotationAdd
BLAST
Domaini350 – 37728C2H2-typeInterPro annotationAdd
BLAST
Domaini378 – 40528C2H2-typeInterPro annotationAdd
BLAST
Domaini406 – 43328C2H2-typeInterPro annotationAdd
BLAST
Domaini434 – 46128C2H2-typeInterPro annotationAdd
BLAST
Domaini462 – 48928C2H2-typeInterPro annotationAdd
BLAST
Domaini490 – 51728C2H2-typeInterPro annotationAdd
BLAST
Domaini518 – 54528C2H2-typeInterPro annotationAdd
BLAST
Domaini546 – 57328C2H2-typeInterPro annotationAdd
BLAST
Domaini574 – 60128C2H2-typeInterPro annotationAdd
BLAST
Domaini602 – 62928C2H2-typeInterPro annotationAdd
BLAST
Domaini630 – 65728C2H2-typeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains KRAB domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.

Family and domain databases

Gene3Di3.30.160.60. 14 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 3 hits.
PF13912. zf-C2H2_6. 2 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 12 hits.
PS50157. ZINC_FINGER_C2H2_2. 14 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O88631-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHRGESCDAD LESEDTRRVS GGRKNYPEPQ CRAGHPGRVS RQQPNRWNHS
60 70 80 90 100
PVGEGCNLPG PLAIYSLFFK EKFKEEKQEM ADSSVNLSQG LLTFRDVTVD
110 120 130 140 150
FSQEEWECLD SAQRALYIEV MLENYSNLVY VENYCICDTV CQHVKTEKES
160 170 180 190 200
CNELGEMLHE PSNCALYNRS DTTEASNNYR CCKDQDASLD SSNPDRLKST
210 220 230 240 250
HTGKERCESK DCAKSSSLCS SIAQDQRTNS TNKEQRQEKY DDHYISTHSL
260 270 280 290 300
MQQAIYIGEN PHQCMKYGKC FSSASSLGVQ QRTDTGNKPY KCNICDKSFT
310 320 330 340 350
ECSSLKEHRK THQRLRAGTN PYKCNDCGKS FSYLSALQSH HKRHTGEKRY
360 370 380 390 400
KCKECGKSYA YRTGLKRHQK IHTAEECYSC QYCGKVFHQL SHFKSHFTLH
410 420 430 440 450
TGEKPYKCNE CHRSFPHYVF FRRHKKNHSL QKSHKCKECG KSFFILSHLK
460 470 480 490 500
THYRIHTGGK PYKCTKCDKL FTQYSHLRRH QRIYTGKKLY RCEVCDKWFT
510 520 530 540 550
LSSSLSRHQK IHTEAKTYKC KDCDIFFNHY SSLRRHQKVH TGERHYTCKQ
560 570 580 590 600
CGKSFTRGST LRVHQRIHTG EKPYKCSECD KSFTQASQLR THQRVHTGEK
610 620 630 640 650
PYVCKECGKS LTTCAILRAH QKIHTGEKPY KCMECDRSYI QYSHLKRHQK
660
VHTGEKHKIV NNVT
Length:664
Mass (Da):77,322
Last modified:November 1, 1998 - v1
Checksum:i9E47FECDD1FB7F4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF080070 mRNA. Translation: AAC29445.1.
PIRiC40984.
UniGeneiMm.12916.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF080070 mRNA. Translation: AAC29445.1.
PIRiC40984.
UniGeneiMm.12916.

3D structure databases

ProteinModelPortaliO88631.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO88631. 1 interaction.
MINTiMINT-1577357.
STRINGi10090.ENSMUSP00000007884.

Proteomic databases

PaxDbiO88631.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:99201. Zfp54.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di3.30.160.60. 14 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 3 hits.
PF13912. zf-C2H2_6. 2 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 12 hits.
PS50157. ZINC_FINGER_C2H2_2. 14 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A cluster of related zinc finger protein genes is deleted in the mouse embryonic lethal mutation tw18."
    Crossley P.H., Little P.F.
    Proc. Natl. Acad. Sci. U.S.A. 88:7923-7927(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Molecular characterization of the mouse Zfp54 gene."
    Shannon M., Stubbs L.
    Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO88631_MOUSE
AccessioniPrimary (citable) accession number: O88631
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.