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Protein
Submitted name:

Integrin alpha E1

Gene
N/A
Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IntegrinUniRule annotationSAAS annotationImported, ReceptorUniRule annotationSAAS annotation

Keywords - Biological processi

Cell adhesionUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin alpha E1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1115 – 113723HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919UniRule annotationAdd
BLAST
Chaini20 – 11671148UniRule annotationPRO_5001425690Add
BLAST

Expressioni

Gene expression databases

GenevisibleiO88340. RN.

Structurei

3D structure databases

ProteinModelPortaliO88340.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini195 – 375181VWFAInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the integrin alpha chain family.UniRule annotationSAAS annotation
Contains FG-GAP repeats.SAAS annotation
Contains VWFA domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG006187.

Family and domain databases

InterProiIPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
IPR032695. Integrin_dom.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01839. FG-GAP. 2 hits.
PF00357. Integrin_alpha. 1 hit.
PF08441. Integrin_alpha2. 1 hit.
PF00092. VWA. 1 hit.
[Graphical view]
PRINTSiPR01185. INTEGRINA.
SMARTiSM00191. Int_alpha. 4 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 2 hits.
PROSITEiPS51470. FG_GAP. 6 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
PS50234. VWFA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O88340-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWLFHTLLC MASLKPQGAF NMDVDWAWVT ALQPGAPAVL SSLLHLDPSN
60 70 80 90 100
NQTCLLVARR SSNRNTAALY RCAISISPDE IACQPVEHIC MPKGRYQGVT
110 120 130 140 150
LVGNHNGVLV CIQVQARKFR SLNSELTGAC SLLTPNLDLQ AQAYFSDLEG
160 170 180 190 200
FLDPGAHVDS GDYCRSKGGS TGEEKKSARR RRTVEEEDEE EDGTEIAIVL
210 220 230 240 250
DGSGSIEPSD FQKAKNFIST MMRNFYEKCF ECNFALVQYG AVIQTEFDLQ
260 270 280 290 300
ESRDINASLA KVQSIVQVKE VTKTASAMQH VLDNIFIPSR GSRKKALKVM
310 320 330 340 350
VVLTDGDIFG DPLNLTTVIN SPKMQGVVRF AIGVGDAFKN NNTYRELKLI
360 370 380 390 400
ASDPKEAHTF KVTNYSALDG LLSKLQQRIV HMEGTVGDAL QYQLAQTGFS
410 420 430 440 450
AQILDKGQVL LGTVGAFNWS GGALLYSTQN GRGCFLNQTA KEDSRTVQYS
460 470 480 490 500
YLGYSLAVLH KAHGISYVAG APRHKLRGAV FELRKEDREE DAFVRRIEGE
510 520 530 540 550
QMGSYFGSVL CPVDIDMDGT TDFLLVAAPF YHIRGEEGRV YVYQVPEQDA
560 570 580 590 600
SFSLAHTLSG HPGLTNSRFG FAMAAVGDIN QDKFTDVAIG APLEGFGAGD
610 620 630 640 650
GASYGSVYIY NGHSGGLYDS PSQQIRASSV ASGLHYFGMS VSGGLDFNGD
660 670 680 690 700
GLADITVGSR DSAVVLRSRP VVDLTVSMTF TPDALPMVFI GKMDVNLCFE
710 720 730 740 750
VDSSVVASEP GLREMFLNFT VDVDVTKQRQ RLQCEDSSGC QSCLRKWNGG
760 770 780 790 800
SFLCEHFWLI STEELCEEDC FSNITIKVTY EFQTSGGRRD YPNPTLDHYK
810 820 830 840 850
EPSAIFQLPY EKDCKNKVFC IAEIQLTTNI SQQELVVGVT KEVTMNISLT
860 870 880 890 900
NSGEDSYMTN MALNYPRNLQ FKKIQKPVSP DVQCDDPKPV ASVLVMNCKI
910 920 930 940 950
GHPILKRSSV NVSVTWQLEE SVFPNRTADI TVTISNSNEK SLARETRSLQ
960 970 980 990 1000
FRHAFIAVLS RPSVMYMNTS QSPSDHKEFF FNVHGENLFG AVFQLQICVP
1010 1020 1030 1040 1050
IKLQDFQIVR VKNLTKTQDH TECTQSQEPA CGSDPVQHVK EWHSVVCAIT
1060 1070 1080 1090 1100
SNKENVTVAA EISVGHTKQL LRDVSELPIL GEISFNKSLY EGLNAENHRT
1110 1120 1130 1140 1150
KITVIFLKEE ETRSLPLIIG SSIGGLLVLV VIIAILFKCG FFKRKYQQLN
1160
LESTRRAQLK ADSLLQD
Length:1,167
Mass (Da):128,970
Last modified:November 1, 1998 - v1
Checksum:iD88A2C38ACDC2AAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020045 mRNA. Translation: AAC23662.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020045 mRNA. Translation: AAC23662.1.

3D structure databases

ProteinModelPortaliO88340.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG006187.

Gene expression databases

GenevisibleiO88340. RN.

Family and domain databases

InterProiIPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
IPR032695. Integrin_dom.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01839. FG-GAP. 2 hits.
PF00357. Integrin_alpha. 1 hit.
PF08441. Integrin_alpha2. 1 hit.
PF00092. VWA. 1 hit.
[Graphical view]
PRINTSiPR01185. INTEGRINA.
SMARTiSM00191. Int_alpha. 4 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 2 hits.
PROSITEiPS51470. FG_GAP. 6 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
PS50234. VWFA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO88340_RAT
AccessioniPrimary (citable) accession number: O88340
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: June 8, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.