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Protein

Blood group Rh(D) polypeptide

Gene

Rhd

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Blood group Rh(D) polypeptide
Alternative name(s):
Erythrocyte membrane glycoprotein Rh30
CD_antigen: CD240D
Gene namesi
Name:Rhd
Synonyms:Rh30, Rhced
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi620451 Rhd

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei13 – 33HelicalSequence analysisAdd BLAST21
Transmembranei43 – 63HelicalSequence analysisAdd BLAST21
Transmembranei76 – 96HelicalSequence analysisAdd BLAST21
Transmembranei113 – 135HelicalSequence analysisAdd BLAST23
Transmembranei137 – 159HelicalSequence analysisAdd BLAST23
Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
Transmembranei215 – 235HelicalSequence analysisAdd BLAST21
Transmembranei244 – 266HelicalSequence analysisAdd BLAST23
Transmembranei272 – 292HelicalSequence analysisAdd BLAST21
Transmembranei294 – 314HelicalSequence analysisAdd BLAST21
Transmembranei335 – 355HelicalSequence analysisAdd BLAST21
Transmembranei372 – 392HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003833271 – 422Blood group Rh(D) polypeptideAdd BLAST422

Post-translational modificationi

Palmitoylated.By similarity

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiO88298
PRIDEiO88298

Expressioni

Gene expression databases

BgeeiENSRNOG00000017130
GenevisibleiO88298 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023187

Structurei

3D structure databases

ProteinModelPortaliO88298
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3796 Eukaryota
ENOG410XTF8 LUCA
GeneTreeiENSGT00390000005787
HOGENOMiHOG000007656
InParanoidiO88298
KOiK06579
OMAiMTHIHNA
OrthoDBiEOG091G06KX
PhylomeDBiO88298
TreeFamiTF314450

Family and domain databases

Gene3Di1.10.3430.10, 1 hit
InterProiView protein in InterPro
IPR029020 Ammonium/urea_transptr
IPR024041 NH4_transpt_AmtB-like_dom
IPR002229 RhesusRHD
PfamiView protein in Pfam
PF00909 Ammonium_transp, 1 hit
PRINTSiPR00342 RHESUSRHD

Sequencei

Sequence statusi: Complete.

O88298-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSKYPRSLR CCLPLWAFGL QVTFILLFYF LIGQDPIQAD HKFMAIYQVI
60 70 80 90 100
QDLTLVAALG FGFLSSSFRR HGWSSVAFSF FMLALGVQGT ILLDYFLNWV
110 120 130 140 150
LDWNMIKNPF SPFLSIQRAT ISTLPLLISA GAVLGKVNLV QLAVMVLVEA
160 170 180 190 200
MTFGAIRVAD KKVFRIEDHI IMMYGHVFGA YFGLTVAWWL SKSLPRRRHE
210 220 230 240 250
NAQTEKVQMT TSSSLFAMLG TLFLWIFWPS INSALLEGTK KKNAVFNTYY
260 270 280 290 300
ALAVSTVTAT SMSALSHPKG KINMVHIHNA VLAGGVAVGA PSCLISSPWI
310 320 330 340 350
AMVLGLTAGL ISIWGAKCPQ VCLSDLLLNP SGIHYTFGLP GLLGALTYYC
360 370 380 390 400
LHIIAESRPS NLWIVTQTIT DVGALSFAMA MGMVTGLLTG CLLSVKVWRA
410 420
PHAVKYFDDQ AFWEFPHLAV EF
Length:422
Mass (Da):46,583
Last modified:November 1, 1998 - v1
Checksum:i3039E4C72464E66A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB015191 mRNA Translation: BAA32440.1
AF531096 mRNA Translation: AAQ10013.1
BC127471 mRNA Translation: AAI27472.1
RefSeqiNP_071950.1, NM_022505.2
UniGeneiRn.1943

Genome annotation databases

EnsembliENSRNOT00000023187; ENSRNOP00000023187; ENSRNOG00000017130
GeneIDi60414
KEGGirno:60414

Similar proteinsi

Entry informationi

Entry nameiRHD_RAT
AccessioniPrimary (citable) accession number: O88298
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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