O88018 (TAL1_STRCO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase 1
EC=2.2.1.2

Gene names

Name:	tal1
Synonyms:	tal
Ordered Locus Names:	SCO6662
ORF Names:	SC5A7.12c

Organism

Streptomyces coelicolor

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00493
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00493
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00493
Subcellular location	Cytoplasm By similarity HAMAP MF_00493.
Sequence similarities	Belongs to the transaldolase family. Type 2 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 381	381	Transaldolase 1 HAMAP MF_00493		PRO_0000173641
Sites
	Active site	149	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	O88018 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 44068BD43598F5B5	FASTA	381	40,407
	10 20 30 40 50 60 MITVTEATAT AGALQRLADQ GVSVWLDDLS RRRIESGNLA ELIRTKNVVG VTTNPSIFQA 70 80 90 100 110 120 AIGSGEGYEE QLADLATRGV TVDEAVRMMT TADVRAAADV LRGVYDASGG RDGRVSIEVD 130 140 150 160 170 180 PRLAHDTAAT VAEARQLSWL VDRPNVMIKI PATKAGLPAI TEVIGAGISV NVTLIFSLER 190 200 210 220 230 240 YREVMDAYLA GLEKAQAAGI DLAGIHSVAS FFVSRVDSEI DKRLSLLGTE EALGLRGRAA 250 260 270 280 290 300 LANARLAYEA YENVFAGDRF TALAGARANA QRPLWASTGV KDPAFRDTLY VEELVAPGTV 310 320 330 340 350 360 NTMPEATLDA AADHGDVRGD TVTGGYAQAR ADLAAVERLG VSYDEVVEQL EQEGVAKFEA 370 380 AWQELLAAVT KSLDSKGVDG E

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL939128 Genomic DNA. Translation: CAA19941.1.
PIR	T35161.
RefSeq	NP_630737.1. NC_003888.3.
3D structure databases
ProteinModelPortal	O88018.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1102101.
GenomeReviews	Gene locus SCO6662 in contig AL645882_GR.
KEGG	sco:SCO6662.
NMPDR	fig|100226.1.peg.6599.
PATRIC	23743245. VBIStrCoe124346_6768.
Phylogenomic databases
HOGENOM	HBG321149.
OMA	ERYREVM.
ProtClustDB	PRK03343.
Family and domain databases
HAMAP	MF_00493. Transaldolase_2. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004732. Transaldolase_2. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
PIRSF	PIRSF036915. Trnald_Bac_Plnt. 1 hit.
TIGRFAMs	TIGR00876. Tal_mycobact. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL1_STRCO

Accession

Primary (citable) accession number: O88018

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 5, 2001
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program