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O88015

- G6PI1_STRCO

UniProt

O88015 - G6PI1_STRCO

Protein

Glucose-6-phosphate isomerase 1

Gene

pgi1

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei358 – 3581Proton donorBy similarity
    Active sitei389 – 3891By similarity
    Active sitei513 – 5131By similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomerase 1 (EC:5.3.1.9)
    Short name:
    GPI 1
    Alternative name(s):
    Phosphoglucose isomerase 1
    Short name:
    PGI 1
    Phosphohexose isomerase 1
    Short name:
    PHI 1
    Gene namesi
    Name:pgi1
    Synonyms:pgi
    Ordered Locus Names:SCO6659
    ORF Names:SC5A7.09c
    OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    Taxonomic identifieri100226 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
    ProteomesiUP000001973: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 550550Glucose-6-phosphate isomerase 1PRO_0000180749Add
    BLAST

    Proteomic databases

    PRIDEiO88015.

    Interactioni

    Protein-protein interaction databases

    STRINGi100226.SCO6659.

    Structurei

    3D structure databases

    ProteinModelPortaliO88015.
    SMRiO88015. Positions 5-547.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.Curated

    Phylogenomic databases

    HOGENOMiHOG000261371.
    KOiK01810.
    OMAiMMVEFDG.
    OrthoDBiEOG64R61J.
    PhylomeDBiO88015.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O88015-1 [UniParc]FASTAAdd to Basket

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    MSDTPKLNQR PEWTALADHA KGTLPHPDLR ELFAQDPGRA ERYVVRVGDL    50
    RIDYSKHLVT DETLALLQEL AAATGVSGLR DAMFRGERIN ITEDRAVLHT 100
    ALRAPRDAVI EVDGENVVPQ VHAVLDKMAG FADRVRSGEW TGHTGRRIRN 150
    VVNIGIGGSD LGPAMAYEAL RAFTDRSLTL RFVSNVDGAD LHEAVRDLDP 200
    AETLFIIASK TFTTIETITN ATSARSWLLD GLGGDEKAVA KHFVALSTNA 250
    EKVADFGIDT ANMFEFWDWV GGRYSFDSAI GLSLMIAIGP DRFREMLDGF 300
    RIVDEHFRNA EAPANAPLLL GLLGVWYGDF LGAQSHAVLP YSHYLSKFTA 350
    YLQQLDMESN GKSVDREGNP VQWQTGPVVW GTPGTNGQHA YYQLIHQGTK 400
    LIPADFIGFA RPVDELSEEL KAQHDLLMAN FFAQTQALAF GKTPDEVRAE 450
    GVPEELVPHK TFRGNHPTTT VLAAELTPSV LGQLIALYEH KVFVQGAIWN 500
    IDSFDQWGVE LGKVLAKRVE PALTEGADVP GLDPSTAALV AAYRELKEVH 550
    Length:550
    Mass (Da):60,424
    Last modified:November 1, 1998 - v1
    Checksum:i4348783E9E4921DF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939128 Genomic DNA. Translation: CAA19938.1.
    PIRiT35158.
    RefSeqiNP_630734.1. NC_003888.3.
    WP_011031083.1. NC_003888.3.

    Genome annotation databases

    EnsemblBacteriaiCAA19938; CAA19938; CAA19938.
    GeneIDi1102098.
    KEGGisco:SCO6659.
    PATRICi23743239. VBIStrCoe124346_6765.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939128 Genomic DNA. Translation: CAA19938.1 .
    PIRi T35158.
    RefSeqi NP_630734.1. NC_003888.3.
    WP_011031083.1. NC_003888.3.

    3D structure databases

    ProteinModelPortali O88015.
    SMRi O88015. Positions 5-547.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 100226.SCO6659.

    Proteomic databases

    PRIDEi O88015.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAA19938 ; CAA19938 ; CAA19938 .
    GeneIDi 1102098.
    KEGGi sco:SCO6659.
    PATRICi 23743239. VBIStrCoe124346_6765.

    Phylogenomic databases

    HOGENOMi HOG000261371.
    KOi K01810.
    OMAi MMVEFDG.
    OrthoDBi EOG64R61J.
    PhylomeDBi O88015.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-471 / A3(2) / M145.

    Entry informationi

    Entry nameiG6PI1_STRCO
    AccessioniPrimary (citable) accession number: O88015
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 2, 2001
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3