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O88015

- G6PI1_STRCO

UniProt

O88015 - G6PI1_STRCO

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Protein
Glucose-6-phosphate isomerase 1
Gene
pgi1, pgi, SCO6659, SC5A7.09c
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei358 – 3581Proton donor By similarity
Active sitei389 – 3891 By similarity
Active sitei513 – 5131 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase 1 (EC:5.3.1.9)
Short name:
GPI 1
Alternative name(s):
Phosphoglucose isomerase 1
Short name:
PGI 1
Phosphohexose isomerase 1
Short name:
PHI 1
Gene namesi
Name:pgi1
Synonyms:pgi
Ordered Locus Names:SCO6659
ORF Names:SC5A7.09c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 550550Glucose-6-phosphate isomerase 1UniRule annotation
PRO_0000180749Add
BLAST

Proteomic databases

PRIDEiO88015.

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO6659.

Structurei

3D structure databases

ProteinModelPortaliO88015.
SMRiO88015. Positions 5-547.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

HOGENOMiHOG000261371.
KOiK01810.
OMAiMMVEFDG.
OrthoDBiEOG64R61J.
PhylomeDBiO88015.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O88015-1 [UniParc]FASTAAdd to Basket

« Hide

MSDTPKLNQR PEWTALADHA KGTLPHPDLR ELFAQDPGRA ERYVVRVGDL    50
RIDYSKHLVT DETLALLQEL AAATGVSGLR DAMFRGERIN ITEDRAVLHT 100
ALRAPRDAVI EVDGENVVPQ VHAVLDKMAG FADRVRSGEW TGHTGRRIRN 150
VVNIGIGGSD LGPAMAYEAL RAFTDRSLTL RFVSNVDGAD LHEAVRDLDP 200
AETLFIIASK TFTTIETITN ATSARSWLLD GLGGDEKAVA KHFVALSTNA 250
EKVADFGIDT ANMFEFWDWV GGRYSFDSAI GLSLMIAIGP DRFREMLDGF 300
RIVDEHFRNA EAPANAPLLL GLLGVWYGDF LGAQSHAVLP YSHYLSKFTA 350
YLQQLDMESN GKSVDREGNP VQWQTGPVVW GTPGTNGQHA YYQLIHQGTK 400
LIPADFIGFA RPVDELSEEL KAQHDLLMAN FFAQTQALAF GKTPDEVRAE 450
GVPEELVPHK TFRGNHPTTT VLAAELTPSV LGQLIALYEH KVFVQGAIWN 500
IDSFDQWGVE LGKVLAKRVE PALTEGADVP GLDPSTAALV AAYRELKEVH 550
Length:550
Mass (Da):60,424
Last modified:November 1, 1998 - v1
Checksum:i4348783E9E4921DF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939128 Genomic DNA. Translation: CAA19938.1.
PIRiT35158.
RefSeqiNP_630734.1. NC_003888.3.
WP_011031083.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAA19938; CAA19938; CAA19938.
GeneIDi1102098.
KEGGisco:SCO6659.
PATRICi23743239. VBIStrCoe124346_6765.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939128 Genomic DNA. Translation: CAA19938.1 .
PIRi T35158.
RefSeqi NP_630734.1. NC_003888.3.
WP_011031083.1. NC_003888.3.

3D structure databases

ProteinModelPortali O88015.
SMRi O88015. Positions 5-547.
ModBasei Search...

Protein-protein interaction databases

STRINGi 100226.SCO6659.

Proteomic databases

PRIDEi O88015.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAA19938 ; CAA19938 ; CAA19938 .
GeneIDi 1102098.
KEGGi sco:SCO6659.
PATRICi 23743239. VBIStrCoe124346_6765.

Phylogenomic databases

HOGENOMi HOG000261371.
KOi K01810.
OMAi MMVEFDG.
OrthoDBi EOG64R61J.
PhylomeDBi O88015.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145.

Entry informationi

Entry nameiG6PI1_STRCO
AccessioniPrimary (citable) accession number: O88015
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: November 1, 1998
Last modified: September 3, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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