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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Vibrio harveyi (Beneckea harveyi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
OrganismiVibrio harveyi (Beneckea harveyi)
Taxonomic identifieri669 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 640640Chaperone protein DnaKPRO_0000078582Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei200 – 2001Phosphothreonine; by autocatalysisBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiO87384.

Expressioni

Inductioni

By stress conditions e.g. heat shock (By similarity).By similarity

Interactioni

Protein-protein interaction databases

STRINGi338187.VIBHAR_01134.

Structurei

3D structure databases

ProteinModelPortaliO87384.
SMRiO87384. Positions 3-383, 390-606.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O87384-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIIGIDLG TTNSCVAVLD GDKPRVIENA EGERTTASVI AYTDGETLVG
60 70 80 90 100
QPGGNVNAVT NPTRYTLFAI KRLIGRRFED EEVQRDIEIM PYKIVKADNG
110 120 130 140 150
DAWVEAKGQK MAAPQVSAEV LKKMKKTAED FLGEEVTGAV ITVPAYFNDA
160 170 180 190 200
QAQATKDAGR IAGLEVKRII NEPTAAALAY GLDKSGGDRT IAVYDLGGGT
210 220 230 240 250
FDISIIEIDE VEGEKTFEVL ATNGDTHLGG EDFDNRLINY LVDEFNKEQG
260 270 280 290 300
INLKNDPLAM QRVKEAAEKA KIELSSTSQT DVNLPYVTAD ATGPKHMNIK
310 320 330 340 350
VTRAKLESLV EDLVQRSLEP LKVALADADL SVNDITDVIL VGGQTRMPMV
360 370 380 390 400
QAKVAEFFGK EARRDVNPDE AVAMGAAVQG GVLAGEVKDV LLLDVTPLSL
410 420 430 440 450
GIETMGAVMT KLVEKNTTIP TKANQVFSTA EDNQSAVTIH VLQGERKQAS
460 470 480 490 500
FNKSLGQFNL EGIQAAPRGM PQIEVTFDLD ADGILHVSAK DKQTGKEQKI
510 520 530 540 550
TIQASGGLSD DDIEKMVQEA EANKEADKKF EELATARNQA DQMIHGTRKQ
560 570 580 590 600
VEEAGEALPA EEKEKIEAAI SELETARKGD DKEAIDAKVQ ALMTAAQKLM
610 620 630 640
EIAQQQAQAQ QAQGGYAGAQ QSQEDDVVDA EFEEVKDDKK
Length:640
Mass (Da):69,077
Last modified:November 1, 1998 - v1
Checksum:i470246409008B5FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY639008 Genomic DNA. Translation: AAT39536.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY639008 Genomic DNA. Translation: AAT39536.1.

3D structure databases

ProteinModelPortaliO87384.
SMRiO87384. Positions 3-383, 390-606.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi338187.VIBHAR_01134.

Proteomic databases

PRIDEiO87384.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and characterization of the dnaK heat shock operon of the marine bacterium Vibrio harveyi."
    Klein G., Zmijewski M., Krzewska J., Czeczatka M., Lipinska B.
    Mol. Gen. Genet. 259:179-189(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiDNAK_VIBHA
AccessioniPrimary (citable) accession number: O87384
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: November 1, 1998
Last modified: November 11, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.