O87361 (O87361_STAAU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nicking enzyme EMBL AAQ17176.1

Submitted name:
OriT nickase EMBL ACZ68642.1
Submitted name:
OriT nickase Nes EMBL AAC61938.1
Submitted name:
OriT relaxase Nes EMBL CAR62405.1

Gene names

Name:	nes EMBL AAC61938.1
ORF Names:	PGO1_p08 EMBL CAR62405.1, SAP014A_018 EMBL ADA61325.1, SAP015D_002 EMBL ADA62799.1, SAP068A_007 EMBL ACZ68642.1, SAP069A_033 EMBL ACZ68723.1, SAP079A_020 EMBL ADA62090.1, SAP080A_038 EMBL ADA62161.1, SAP082A_025 EMBL ADA62197.1, VRA0057 EMBL AAQ17176.1

Encoded on

Plasmid SAP068A Ref.5 Ref.6 Ref.8 EMBL ACZ68642.1
Plasmid pGO1 Ref.4 Ref.8 EMBL CAR62405.1
Plasmid pLW043 Ref.2 Ref.3 Ref.8 EMBL AAQ17176.1
Plasmid SAP014A Ref.5 Ref.6 Ref.8 EMBL ADA61325.1
Plasmid SAP015B Ref.5 Ref.6 Ref.8 EMBL ADA62799.1
Plasmid SAP082A Ref.5 Ref.7 Ref.8 EMBL ADA62197.1
Plasmid SAP069A Ref.5 Ref.6 Ref.8 EMBL ACZ68723.1
Plasmid SAP080A Ref.5 Ref.7 Ref.8 EMBL ADA62161.1
Plasmid SAP079A Ref.5 Ref.7 Ref.8 EMBL ADA62090.1
Plasmid pSK41 Ref.1 Ref.8 EMBL AAC61938.1

Organism

Staphylococcus aureus EMBL AAC61938.1

Taxonomic identifier

1280 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcaceae › Staphylococcus

Protein attributes

Sequence length	665 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 4HTE Plasmid EMBL AAC61938.1
Gene Ontology (GO)
Biological_process	unidirectional conjugation Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O87361 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 629A3615725E0D50	FASTA	665	78,909
	10 20 30 40 50 60 MAMYHFQNKF VSKANGQSAT AKSAYNSASR IKDFKENEFK DYSNKQCDYS EILLPNNADD 70 80 90 100 110 120 KFKDREYLWN KVHDVENRKN SQVAREIIIG LPNEFDPNSN IELAKEFAES LSNEGMIVDL 130 140 150 160 170 180 NIHKINEENP HAHLLCTLRG LDKNNEFEPK RKGNDYIRDW NTKEKHNEWR KRWENVQNKH 190 200 210 220 230 240 LEKNGFSVRV SADSYKNQNI DLEPTKKEGW KARKFEDETG KKSSISKHNE SIKKRNQQKI 250 260 270 280 290 300 DKMFNEVDDM KSHKLNAFSY MNKSDSTTLK NMAKDLKIYV TPINMYKENE RLYDLKQKTS 310 320 330 340 350 360 LITDDEDRLN KIEDIEDRQK KLESINEVFE KQAGIFFDKN YPDQSLNYSD DEKIFITRTI 370 380 390 400 410 420 LNDRDVLPAN NELEDIVKEK RIKEAQISLN TVLGNRDISL ESIEKESNFF ADKLSNILEK 430 440 450 460 470 480 NNLSFDDVLE NKHEGMEDSL KIDYYTNKLE VFRNAENILE DYYDVQIKEL FTDDEDYKAF 490 500 510 520 530 540 NEVTDIKEKQ QLIDFKTYHG TENTIEMLET GNFIPKYSDE DRKYITEQVK LLQEKEFKPN 550 560 570 580 590 600 KNQHDKFVFG AIQKKLLSEY DFDYSDNNDL KHLYQESNEV GDEISKDNIE EFYEGNDILV 610 620 630 640 650 660 DKETYNNYNR KQQAYGLINA GLDSMIFNFN EIFRERMPKY INHQYKGKNH SKQRHELKNK RGMHL

References

[1]	"Complete nucleotide sequence of pSK41: evolution of staphylococcal conjugative multiresistance plasmids." Berg T., Firth N., Apisiridej S., Hettiaratchi A., Leelaporn A., Skurray R.A. J. Bacteriol. 180:4350-4359(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus." Weigel L.M., Clewell D.B., Gill S.R., Clark N.C., McDougal L.K., Flannagan S.E., Kolonay J.F., Shetty J., Killgore G.E., Tenover F.C. Science 302:1569-1571(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Gill S., Kolonay J., Shetty J., Tenover F., Weigel L. Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	"Complete nucleotide sequence of pGO1, the prototype conjugative plasmid from the staphylococci." Caryl J.A., O'Neill A.J. Plasmid 0:0-0(2009) Cited for: NUCLEOTIDE SEQUENCE.
[5]	Gill J., Borman J., Shetty J., Hostetler J., Durkin S., Montgomery B. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: CDC58 EMBL ADA61325.1, CDC61 EMBL ADA62799.1, CDCGA672 EMBL ADA62090.1, CDCPANICU EMBL ADA62197.1, CDCTN147 EMBL ADA62161.1, PM64 EMBL ACZ68642.1 and PM79 EMBL ACZ68723.1.
[6]	Summers A.O., Shearer J., Wireman J. Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: CDC58 EMBL ADA61325.1, CDC61 EMBL ADA62799.1, PM64 EMBL ACZ68642.1 and PM79 EMBL ACZ68723.1.
[7]	"Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States." McDougal L.K., Fosheim G.E., Nicholson A., Bulens S.N., Limbago B.M., Shearer J.E., Summers A.O., Patel J.B. Antimicrob. Agents Chemother. 54:3804-3811(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CDCGA672 EMBL ADA62090.1, CDCPANICU EMBL ADA62197.1 and CDCTN147 EMBL ADA62161.1.
[8]	"Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus." Edwards J.S., Betts L., Frazier M.L., Pollet R.M., Kwong S.M., Walton W.G., Ballentine W.K., Huang J.J., Habibi S., Del Campo M., Meier J.L., Dervan P.B., Firth N., Redinbo M.R. Proc. Natl. Acad. Sci. U.S.A. 110:2804-2809(2013) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS) OF 243-594.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF051917 Genomic DNA. Translation: AAC61938.1.
AE017171 Genomic DNA. Translation: AAQ17176.1.
GQ900421 Genomic DNA. Translation: ACZ68642.1.
GQ900422 Genomic DNA. Translation: ACZ68723.1.
GQ900379 Genomic DNA. Translation: ADA61325.1.
GQ900432 Genomic DNA. Translation: ADA62090.1.
GQ900433 Genomic DNA. Translation: ADA62161.1.
GQ900434 Genomic DNA. Translation: ADA62197.1.
GQ900501 Genomic DNA. Translation: ADA62799.1.
FM207042 Genomic DNA. Translation: CAR62405.1.

RefSeq

NP_863609.1. NC_005024.1.
NP_878032.1. NC_005054.1.
YP_002790904.1. NC_012547.1.
YP_006937638.1. NC_013320.1.
YP_006938308.1. NC_013338.1.
YP_006938388.1. NC_013339.1.
YP_006938483.1. NC_013342.1.
YP_006938553.1. NC_013343.1.
YP_006938590.1. NC_013344.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4HTE	X-ray	3.00	A	243-594	[»]

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

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Genome annotation databases

GeneID

13874788.
13875504.
13875557.
13875654.
13875726.
13875763.
2598297.
2598342.
7751510.

Phylogenomic databases

ProtClustDB

CLSK523995.

Family and domain databases

InterPro

IPR005053. MobA_MobL.
[Graphical view]

Pfam

PF03389. MobA_MobL. 1 hit.
[Graphical view]

ProtoNet

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Entry information

Entry name

O87361_STAAU

Accession

Primary (citable) accession number: O87361

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)