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Protein

Probable hydrogen peroxide-inducible genes activator

Gene

oxyR

Organism
Mycobacterium marinum
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi25 – 44H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable hydrogen peroxide-inducible genes activator
Gene namesi
Name:oxyR
OrganismiMycobacterium marinum
Taxonomic identifieri1781 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057361 – 311Probable hydrogen peroxide-inducible genes activatorAdd BLAST311

Proteomic databases

PRIDEiO87324.

Structurei

3D structure databases

ProteinModelPortaliO87324.
SMRiO87324.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 65HTH lysR-typePROSITE-ProRule annotationAdd BLAST58

Phylogenomic databases

eggNOGiENOG4105C5Q. Bacteria.
ENOG410XNR2. LUCA.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS50931. HTH_LYSR. 1 hit.

Sequencei

Sequence statusi: Complete.

O87324-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKSYQPTL AGLRAFVAVA EKQHFGSAAN ALGVSQSTLS QALAALEAGL
60 70 80 90 100
NLHLVERSTR RVFLTTEGRS LLPHAQAAVE AVEAFTTAAA GEADPLNGSI
110 120 130 140 150
RFGIIPTVAP YVLPTVLAGL TRRLPTLTVR VIEDQTERLL TALREGSLDT
160 170 180 190 200
ALIALPADYR GLTEMPIYEE DFVLALPPGH PMADRHGVPV AALSELPLLL
210 220 230 240 250
LDEGHCLRDQ ALDVCQNAGV RAELADTRAA SLATAVQCVN GGLGVTLIPQ
260 270 280 290 300
SAVSVEAARS RVGLAHFAAP TPGRRIGLVY RASSGRDEAY RQLAAIMGES
310
IGNEQQVRLV N
Length:311
Mass (Da):32,865
Last modified:November 1, 1998 - v1
Checksum:i8111B2726090C096
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF034861 Genomic DNA. Translation: AAC61302.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiOXYR_MYCMR
AccessioniPrimary (citable) accession number: O87324
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: July 5, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program