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Protein

Chemotaxis protein methyltransferase 1

Gene

cheR1

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.By similarity

Catalytic activityi

S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei72S-adenosyl-L-methionineBy similarity1
Binding sitei74S-adenosyl-L-methionineBy similarity1
Binding sitei78S-adenosyl-L-methionineBy similarity1
Binding sitei115S-adenosyl-L-methionineBy similarity1
Binding sitei144S-adenosyl-L-methionineBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-3412-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis protein methyltransferase 1 (EC:2.1.1.80)
Gene namesi
Name:cheR1
Ordered Locus Names:PA3348
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3348

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001760371 – 274Chemotaxis protein methyltransferase 1Add BLAST274

Proteomic databases

PaxDbiO87131

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3348

Structurei

Secondary structure

1274
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 19Combined sources14
Helixi28 – 42Combined sources15
Helixi47 – 53Combined sources7
Beta strandi58 – 60Combined sources3
Helixi61 – 69Combined sources9
Turni76 – 79Combined sources4
Helixi81 – 88Combined sources8
Helixi90 – 95Combined sources6
Beta strandi103 – 108Combined sources6
Turni111 – 113Combined sources3
Helixi114 – 129Combined sources16
Beta strandi138 – 144Combined sources7
Helixi148 – 155Combined sources8
Beta strandi157 – 159Combined sources3
Helixi160 – 163Combined sources4
Beta strandi164 – 166Combined sources3
Helixi169 – 175Combined sources7
Beta strandi176 – 178Combined sources3
Beta strandi183 – 186Combined sources4
Helixi188 – 192Combined sources5
Beta strandi194 – 198Combined sources5
Helixi206 – 208Combined sources3
Beta strandi211 – 215Combined sources5
Helixi220 – 222Combined sources3
Helixi225 – 238Combined sources14
Beta strandi239 – 246Combined sources8
Turni257 – 259Combined sources3
Beta strandi260 – 264Combined sources5
Beta strandi266 – 273Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5XLXX-ray1.97A/B/C/D1-274[»]
5XLYX-ray1.76A1-274[»]
5Y4RX-ray2.30A/B2-274[»]
5Y4SX-ray3.40A/B/C/D/E/F/G/H/I/J2-274[»]
ProteinModelPortaliO87131
SMRiO87131
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 274CheR-type methyltransferasePROSITE-ProRule annotationAdd BLAST274

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni200 – 201S-adenosyl-L-methionine bindingBy similarity2
Regioni217 – 218S-adenosyl-L-methionine bindingBy similarity2

Phylogenomic databases

eggNOGiENOG4105BZU Bacteria
ENOG410XNMH LUCA
HOGENOMiHOG000254354
InParanoidiO87131
KOiK00575
OMAiKSRVEFR
PhylomeDBiO87131

Family and domain databases

Gene3Di1.10.155.10, 1 hit
InterProiView protein in InterPro
IPR026024 Chemotaxis_MeTrfase_CheR
IPR022642 CheR_C
IPR000780 CheR_MeTrfase
IPR022641 CheR_N
IPR036804 CheR_N_sf
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01739 CheR, 1 hit
PF03705 CheR_N, 1 hit
PIRSFiPIRSF000410 CheR, 1 hit
PRINTSiPR00996 CHERMTFRASE
SMARTiView protein in SMART
SM00138 MeTrc, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS50123 CHER, 1 hit

Sequencei

Sequence statusi: Complete.

O87131-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAANADFEL FRVFLEKTCG IVLGSNKQYL VSSRLNKLME QQGIKSLGEL
60 70 80 90 100
VQRIQTQRGG LREMVVDAMT TNETLWFRDT YPFEVLKQRV LPELIKANGG
110 120 130 140 150
QRLRIWSAAC SSGQEPYSLS MAIDEFEKTN LGQLKAGVQI VATDLSGSML
160 170 180 190 200
TAAKAGEYDT LAMGRGLSPE RLQRYFDAKG PGRWAVKPAI RSRVEFRALN
210 220 230 240 250
LLDSYASLGK FDMVFCRNVL IYFSAEVKRD ILLRIHGTLK PGGYLFLGAS
260 270
EALNNLPDHY QMVQCSPGII YRAK
Length:274
Mass (Da):30,647
Last modified:November 1, 1998 - v1
Checksum:i9B5DD76DFD2012BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012768 Genomic DNA Translation: BAA33556.1
AE004091 Genomic DNA Translation: AAG06736.1
PIRiA83227
RefSeqiNP_252038.1, NC_002516.2
WP_003091728.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG06736; AAG06736; PA3348
GeneIDi882515
KEGGipae:PA3348
PATRICifig|208964.12.peg.3507

Similar proteinsi

Entry informationi

Entry nameiCHER1_PSEAE
AccessioniPrimary (citable) accession number: O87131
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

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