Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Endo-1,4-beta-xylanase

Gene

xynA

Organism
Clostridium thermocellum (Ruminiclostridium thermocellum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Pathwayi: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei122NucleophilePROSITE-ProRule annotation1
Active sitei212Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidasePROSITE-ProRule annotation, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradation, Xylan degradationPROSITE-ProRule annotationImported

Enzyme and pathway databases

UniPathwayiUPA00114.

Protein family/group databases

CAZyiCBM6. Carbohydrate-Binding Module Family 6.
GH11. Glycoside Hydrolase Family 11.
mycoCLAPiXYN11A_CLOTH.

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanasePROSITE-ProRule annotation (EC:3.2.1.8PROSITE-ProRule annotation)
Gene namesi
Name:xynAImported
OrganismiClostridium thermocellum (Ruminiclostridium thermocellum)Imported
Taxonomic identifieri1515 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500416029429 – 683Endo-1,4-beta-xylanaseSequence analysisAdd BLAST655

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2C71X-ray1.05A477-683[»]
2C79X-ray1.50A477-683[»]
ProteinModelPortaliO87119.
SMRiO87119.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO87119.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 225GH11 (glycosyl hydrolase family 11)InterPro annotationAdd BLAST195
Domaini252 – 374CBM6 (carbohydrate binding type-6)InterPro annotationAdd BLAST123
Domaini388 – 456DockerinInterPro annotationAdd BLAST69
Domaini480 – 658NodB homologyInterPro annotationAdd BLAST179

Sequence similaritiesi

Belongs to the glycosyl hydrolase 11 (cellulase G) family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4107T94. Bacteria.
COG0726. LUCA.
COG5498. LUCA.

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
2.60.120.260. 1 hit.
InterProiView protein in InterPro
IPR006584. Cellulose-bd_IV.
IPR005084. CMB_fam6.
IPR013320. ConA-like_dom.
IPR002105. Dockerin_1_rpt.
IPR016134. Dockerin_dom.
IPR018247. EF_Hand_1_Ca_BS.
IPR008979. Galactose-bd-like.
IPR013319. GH11/12.
IPR018208. GH11_AS_1.
IPR033119. GH11_AS_2.
IPR033123. GH11_dom.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR001137. Glyco_hydro_11.
IPR002509. NODB_dom.
PfamiView protein in Pfam
PF03422. CBM_6. 1 hit.
PF00404. Dockerin_1. 2 hits.
PF00457. Glyco_hydro_11. 1 hit.
PF01522. Polysacc_deac_1. 1 hit.
PRINTSiPR00911. GLHYDRLASE11.
SMARTiView protein in SMART
SM00606. CBD_IV. 1 hit.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF49899. SSF49899. 1 hit.
SSF63446. SSF63446. 1 hit.
SSF88713. SSF88713. 1 hit.
PROSITEiView protein in PROSITE
PS51175. CBM6. 1 hit.
PS00448. CLOS_CELLULOSOME_RPT. 1 hit.
PS51766. DOCKERIN. 1 hit.
PS00018. EF_HAND_1. 1 hit.
PS00776. GH11_1. 1 hit.
PS00777. GH11_2. 1 hit.
PS51761. GH11_3. 1 hit.
PS51677. NODB. 1 hit.

Sequencei

Sequence statusi: Complete.

O87119-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQKLLITFL ILITFTVSLT LFPVNVRADV VITSNQTGTH GGYNFEYWKD
60 70 80 90 100
TGNGTMVLKD GGAFSCEWSN INNILFRKGF KYDETKTHDQ LGYITVTYSC
110 120 130 140 150
NYQPNGNSYL GVYGWTSNPL VEYYIIESWG TWRPPGATPK GTITVDGGTY
160 170 180 190 200
EIYETTRVNQ PSIKGTATFQ QYWSVRTSKR TSGTISVTEH FKAWERLGMK
210 220 230 240 250
MGKMYEVALV VEGYQSSGKA DVTSMTITVG NAPSTSSPPG PTPEPTPRSA
260 270 280 290 300
FSKIEAEEYN SLKSSTIQTI GTSDGGSGIG YIESGDYLVF NKINFGNGAN
310 320 330 340 350
SFKARVASGA DTPTNIQLRL GSPTGTLIGT LTVASTGGWN NYEEKSCSIT
360 370 380 390 400
NTTGQHDLYL VFSGPVNIDY FIFDSNGVNP TPTSQPQQGQ VLGDLNGDKQ
410 420 430 440 450
VNSTDYTALK RHLLNITRLS GTALANADLN GDGKVDSTDL MILHRYLLGI
460 470 480 490 500
ISSFPRSNPQ PSSNPQPSSN PQPTINPNAK LVALTFDDGP DNVLTARVLD
510 520 530 540 550
KLDKYNVKAT FMVVGQRVND STAAIIRRMV NSGHEIGNHS WSYSGMANMS
560 570 580 590 600
PDQIRKSIAD TNAVIQKYAG TTPKFFRPPN LETSPTLFNN VDLVFVGGLT
610 620 630 640 650
ANDWIPSTTA EQRAAAVING VRDGTIILLH DVQPEPHPTP EALDIIIPTL
660 670 680
KSRGYEFVTL TELFTLKGVP IDPSVKRMYN SVP
Length:683
Mass (Da):74,513
Last modified:November 1, 1998 - v1
Checksum:iC5F39D05C2145ABF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010958 Genomic DNA. Translation: BAA33543.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO87119_CLOTM
AccessioniPrimary (citable) accession number: O87119
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: July 5, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources