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Protein

Polar flagellin F

Gene

flaF

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-2318-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Polar flagellin F
Gene namesi
Name:flaF
Ordered Locus Names:VP2261
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002493 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 377377Polar flagellin FPRO_0000182657Add
BLAST

Interactioni

Subunit structurei

Heteropolymer of multiple flagellin subunits including FlaA, FlaB/D, FlaC, FlaE and FlaF.

Protein-protein interaction databases

STRINGi223926.VP2261.

Structurei

3D structure databases

ProteinModelPortaliO87081.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili98 – 13134Sequence analysisAdd
BLAST
Coiled coili302 – 33938Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the bacterial flagellin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
KOiK02406.
OMAiNIHENIA.
OrthoDBiEOG6M9DVB.

Family and domain databases

Gene3Di1.20.1330.10. 2 hits.
InterProiIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
IPR010810. Flagellin_hook_IN_motif.
[Graphical view]
PfamiPF00700. Flagellin_C. 1 hit.
PF07196. Flagellin_IN. 1 hit.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSiPR00207. FLAGELLIN.

Sequencei

Sequence statusi: Complete.

O87081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAITVNTNVA ALVAQRHLTS ATDMLNQSME RLSSGKRINS AKDDAAGLQI
60 70 80 90 100
SNRLQSQMSG LDVAVRNAND GISIMQTAEG AMNEVTNIMQ RMRDLSLQSA
110 120 130 140 150
NGSNSQVERT ALQEEVTALN DELNRIAETT SFGGRKLLNG AFGKSSFQIG
160 170 180 190 200
AASGEAVQIE LKSMRTDGLE MGGFSYVAQG RADSDWQVKE NANDLTMSFI
210 220 230 240 250
NRSGETEKIQ INAKSGDDIE ELATYINGQT DKVTASVNEK GQLQIFMAGE
260 270 280 290 300
DTAGTISFSG DLASELGMSL KGYDAVNNLN ITTVGGAQQA VAVLDTAMKF
310 320 330 340 350
VDSQRAELGA YQNRFNHAIN NLDNIHENLA ASNSRIQDTD YAKETTQMVK
360 370
QQILQQVSTT ILAQAKQAPN LALTLLG
Length:377
Mass (Da):40,501
Last modified:April 4, 2003 - v2
Checksum:iD8EEA4338CF0E6BB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti59 – 591S → R in AAC27808 (PubMed:10850984).Curated
Sequence conflicti107 – 1071V → A in AAC27808 (PubMed:10850984).Curated
Sequence conflicti141 – 1411A → T in AAC27808 (PubMed:10850984).Curated
Sequence conflicti200 – 2001I → T in AAC27808 (PubMed:10850984).Curated
Sequence conflicti215 – 2151S → A in AAC27808 (PubMed:10850984).Curated
Sequence conflicti251 – 2511D → E in AAC27808 (PubMed:10850984).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069392 Genomic DNA. Translation: AAC27808.1.
BA000031 Genomic DNA. Translation: BAC60524.1.
RefSeqiNP_798640.1. NC_004603.1.
WP_005481067.1. NC_004603.1.

Genome annotation databases

EnsemblBacteriaiBAC60524; BAC60524; BAC60524.
GeneIDi1189774.
KEGGivpa:VP2261.
PATRICi20142670. VBIVibPar50997_2164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069392 Genomic DNA. Translation: AAC27808.1.
BA000031 Genomic DNA. Translation: BAC60524.1.
RefSeqiNP_798640.1. NC_004603.1.
WP_005481067.1. NC_004603.1.

3D structure databases

ProteinModelPortaliO87081.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi223926.VP2261.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC60524; BAC60524; BAC60524.
GeneIDi1189774.
KEGGivpa:VP2261.
PATRICi20142670. VBIVibPar50997_2164.

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
KOiK02406.
OMAiNIHENIA.
OrthoDBiEOG6M9DVB.

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-2318-MONOMER.

Family and domain databases

Gene3Di1.20.1330.10. 2 hits.
InterProiIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
IPR010810. Flagellin_hook_IN_motif.
[Graphical view]
PfamiPF00700. Flagellin_C. 1 hit.
PF07196. Flagellin_IN. 1 hit.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSiPR00207. FLAGELLIN.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the polar flagellar gene system of Vibrio parahaemolyticus."
    Kim Y.-K., McCarter L.L.
    J. Bacteriol. 182:3693-3704(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: BB22.
  2. "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae."
    Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K., Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S., Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.
    Lancet 361:743-749(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RIMD 2210633.

Entry informationi

Entry nameiFLAF_VIBPA
AccessioniPrimary (citable) accession number: O87081
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: April 4, 2003
Last modified: December 9, 2015
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

V.parahaemolyticus possesses two flagellar systems: a single polar flagellum propels the bacterium in liquid (swimming), while multiple lateral (peritrichous) flagella move the bacterium over surfaces (swarming). The polar flagellum is synthesized constitutively but lateral flagella are produced only under conditions in which the polar flagellum is not functional.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.