Chlorophenol-4-monooxygenase component 1

Preferred order of sections

Names and origin

Protein names

Submitted name:
Chlorophenol-4-monooxygenase component 1 EMBL AAC23547.1

Gene names

Name:

tftC EMBL AAC23547.1

Organism

Burkholderia cepacia (Pseudomonas cepacia) EMBL AAC23547.1

Taxonomic identifier

292 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	179 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	FAD PDB 3K88 PDB 3K87 Flavoprotein PDB 3K88 PDB 3K87 NAD PDB 3K88 Nucleotide-binding PDB 3K88 PDB 3K87
Molecular function	Monooxygenase EMBL AAC23547.1 Oxidoreductase
Technical term	3D-structure PDB 3K88 PDB 3K87 PDB 3K86
Gene Ontology (GO)
Molecular function	FMN binding Inferred from electronic annotation. Source: InterPro flavin reductase activity Inferred from electronic annotation. Source: InterPro monooxygenase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Nucleotide binding

48 – 51

4

FAD PDB 3K88 PDB 3K87

Nucleotide binding

54 – 57

4

NAD PDB 3K88

Nucleotide binding

65 – 71

7

FAD PDB 3K88 PDB 3K87

Nucleotide binding

104 – 109

6

FAD PDB 3K88 PDB 3K87

Nucleotide binding

166 – 169

4

NAD PDB 3K88

Sites

Binding site

99

1

FAD; via carbonyl oxygen PDB 3K88 PDB 3K87

Binding site

144

1

FAD PDB 3K88

Binding site

145

1

NAD PDB 3K88

Binding site

166

1

FAD PDB 3K88 PDB 3K87

Sequences

Sequence

Length

Mass (Da)

Tools

O87008 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 8944587144256B80
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FASTA

179

19,028

        10         20         30         40         50         60 
MHAGEAVQQL KKAFETVASF DFRDALSKAS TPVTVVATNG PFGLAGLTCS AVCSVCDRPP 

        70         80         90        100        110        120 
TVLLCINRKS YAAGIIKSNG VLSVNWLAAG QAVISQTFAG VGSVPMEERF ADKGWQTIAT 

       130        140        150        160        170 
GAPYRMDAAV SFDCTIANIV DVGSHSVIFA EVVARNHAEE CTPLIYHRRQ YATTRSLAE

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References

[1]	"Genes for 2,4,5-trichlorophenoxyacetic acid metabolism in Burkholderia cepacia AC1100: characterization of the tftC and tftD genes and locations of the tft operons on multiple replicons." Hubner A., Danganan C.E., Xun L., Chakrabarty A.M., Hendrickson W. Appl. Environ. Microbiol. 64:2086-2093(1998) [PubMed: 9603818] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: AC1100 EMBL AAC23547.1.
[2]	Gisi M.R., Xun L. Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: AC1100 EMBL AAC23547.1.
[3]	"Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:FAD oxidoreductase (TftC) of Burkholderia cepacia AC1100." Webb B.N., Ballinger J.W., Kim E., Belchik S.M., Lam K.S., Youn B., Nissen M.S., Xun L., Kang C. J. Biol. Chem. 285:2014-2027(2010) [PubMed: 19915006] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH FAD AND NAD.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U83405 Genomic DNA. Translation: AAC23547.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3K86	X-ray	2.00	A/B	1-179	[»]
3K87	X-ray	2.00	A/B	1-179	[»]
3K88	X-ray	2.00	A/B	1-179	[»]

ProteinModelPortal

O87008.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR002563. Flavin_Rdtase_FMN-bd.
IPR012349. Split_barrel_FMN-bd.
IPR009002. Split_barrel_FMN-bd-related.
[Graphical view]

Gene3D

G3DSA:2.30.110.10. PNPOx_FMN_bd. 1 hit.

Pfam

PF01613. Flavin_Reduct. 1 hit.
[Graphical view]

SMART

SM00903. Flavin_Reduct. 1 hit.
[Graphical view]

SUPFAM

SSF50475. FMN_binding. 1 hit.

ProtoNet

Search...

Entry information

Entry name

O87008_BURCE

Accession

Primary (citable) accession number: O87008

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	September 21, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)