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Protein

Alpha-glycerophosphate oxidase

Gene

glpO

Organism
Enterococcus casseliflavus (Enterococcus flavescens)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + O2 = glycerone phosphate + H2O2.

Cofactori

Pathwayi: glycerophospholipid metabolism

This protein is involved in the pathway glycerophospholipid metabolism, which is part of Membrane lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway glycerophospholipid metabolism and in Membrane lipid metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 49FADSequence analysisAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processGlycerol metabolism
LigandFAD, Flavoprotein

Enzyme and pathway databases

SABIO-RKiO86963
UniPathwayiUPA00940

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-glycerophosphate oxidase (EC:1.1.3.21)
Alternative name(s):
Glycerol-3-phosphate oxidase
Gene namesi
Name:glpO
OrganismiEnterococcus casseliflavus (Enterococcus flavescens)
Taxonomic identifieri37734 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001261072 – 609Alpha-glycerophosphate oxidaseAdd BLAST608

Proteomic databases

PRIDEiO86963

Structurei

3D structure databases

ProteinModelPortaliO86963
SMRiO86963
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C6V Bacteria
COG0578 LUCA

Family and domain databases

Gene3Di1.10.8.870, 1 hit
InterProiView protein in InterPro
IPR031656 DAO_C
IPR038299 DAO_C_sf
IPR006076 FAD-dep_OxRdtase
IPR036188 FAD/NAD-bd_sf
IPR000447 G3P_DH_FAD-dep
PANTHERiPTHR11985 PTHR11985, 1 hit
PfamiView protein in Pfam
PF01266 DAO, 1 hit
PF16901 DAO_C, 1 hit
PRINTSiPR01001 FADG3PDH
SUPFAMiSSF51905 SSF51905, 2 hits
PROSITEiView protein in PROSITE
PS00977 FAD_G3PDH_1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O86963-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFSQKDRKE TIQETAKTTY DVLIIGGGIT GAGVAVQTAA AGMKTVLLEM
60 70 80 90 100
QDFAEGTSSR STKLVHGGIR YLKTFDVEVV ADTVRERAIV QQIAPHIPKP
110 120 130 140 150
DPMLLPIYDE PGATFSLFSV KVAMDLYDRL ANVTGSKYEN YLLTKEEVLA
160 170 180 190 200
REPQLQAENL VGGGVYLDFR NNDARLVIEN IKRAQADGAA MISKAKVVGI
210 220 230 240 250
LHDEQGIING VEVEDQLTNE RFEVHAKVVI NTTGPWSDIV RQLDKNDELP
260 270 280 290 300
PQMRPTKGVH LVVDREKLKV PQPTYFDTGK NDGRMVFVVP RENKTYFGTT
310 320 330 340 350
DTDYTGDFAH PTVTQEDVDY LLTIVNERFP HAQITLDDIE ASWAGLRPLI
360 370 380 390 400
TNNGGSDYNG GGKGKLSDES FEQIVESVKE YLADERQRPV VEKAVKQAQE
410 420 430 440 450
RVEASKVDPS QVSRGSSLER SKDGLLTLAG GKITDYRLMA EGAVKRINEL
460 470 480 490 500
LQESGASFEL VDSTTYPVSG GELDAANVEE ELAKLADQAQ TAGFNEAAAT
510 520 530 540 550
YLAHLYGSNL PQVLNYKTKF EGLDEKESTA LNYSLHEEMV LTPVDYLLRR
560 570 580 590 600
TNHILFMRDT LDDVKAGVVA AMTDFFGWSE EEKAAHVLEL NQVIAESDLT

ALKGGKKDE
Length:609
Mass (Da):67,216
Last modified:January 23, 2007 - v3
Checksum:i38A17281C16990F6
GO

Mass spectrometryi

Molecular mass is 67082 Da from positions 2 - 609. Determined by ESI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U57498 Genomic DNA Translation: AAC34739.1

Similar proteinsi

Entry informationi

Entry nameiGLPO_ENTCA
AccessioniPrimary (citable) accession number: O86963
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 82 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing
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Main funding by: National Institutes of Health