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Protein
Submitted name:

Putative two-component sensor

Gene

SCO6353

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Two-component regulatory systemSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative two-component sensorImported
Gene namesi
Ordered Locus Names:SCO6353Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 5124HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

PhosphoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO6353.

Structurei

3D structure databases

ProteinModelPortaliO86622.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini194 – 24754HAMPInterPro annotationAdd
BLAST
Domaini255 – 459205Histidine kinaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG4107ISH. Bacteria.
COG0642. LUCA.
HOGENOMiHOG000115203.
InParanoidiO86622.
OMAiTMTDQAT.
OrthoDBiEOG6G4VQG.
PhylomeDBiO86622.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003660. HAMP_dom.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O86622-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGTRHRTRP ALTAFLHRLA PRTLRGRLSL VALTTAALLM LILTVAFNAV
60 70 80 90 100
AQHRLQHQAD DELRTRAAAV ATTIDTTGTT VRVLETSNDA LLDTNVWIYA
110 120 130 140 150
DGRLLEEPPN AGPLTRVADA LAGHGGRRCV TAGVDGPLRL CSQPVSGDNS
160 170 180 190 200
EATVVTALGL SPYRSSADTL LLGSLALDAV MLACTYALTR LAVGRALRPV
210 220 230 240 250
RTMTDQATQW SAVASEERFG HTRHPSELTR LGTSLDAILD RIRTLLRHER
260 270 280 290 300
QLTGELSHEL RTPLSRIIAE LDWWQTRPRT ADQTHATHKV IAEAAQSMRT
310 320 330 340 350
ICDTLLDDAR GGAPTAPGTA EILPTLRRLT EVLDAPSHLT VTADGPPLEA
360 370 380 390 400
GVPPALLERI ISPLLTNASR YARSKITVHA YRAPDGVRIE VIDDGPGVPP
410 420 430 440 450
PFAGQLFEPG RRADPGDGHS GAGLGLPLAR RLARSAGGEM TYDPDHTPGA

RFVVSLPAG
Length:459
Mass (Da):49,137
Last modified:November 1, 1998 - v1
Checksum:i7189FF2EFA11B367
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939127 Genomic DNA. Translation: CAA20084.1.
PIRiT29443.
RefSeqiNP_630445.1. NC_003888.3.
WP_011030850.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAA20084; CAA20084; CAA20084.
GeneIDi1101794.
KEGGisco:SCO6353.
PATRICi23742636. VBIStrCoe124346_6465.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939127 Genomic DNA. Translation: CAA20084.1.
PIRiT29443.
RefSeqiNP_630445.1. NC_003888.3.
WP_011030850.1. NC_003888.3.

3D structure databases

ProteinModelPortaliO86622.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO6353.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAA20084; CAA20084; CAA20084.
GeneIDi1101794.
KEGGisco:SCO6353.
PATRICi23742636. VBIStrCoe124346_6465.

Phylogenomic databases

eggNOGiENOG4107ISH. Bacteria.
COG0642. LUCA.
HOGENOMiHOG000115203.
InParanoidiO86622.
OMAiTMTDQAT.
OrthoDBiEOG6G4VQG.
PhylomeDBiO86622.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003660. HAMP_dom.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145Imported.

Entry informationi

Entry nameiO86622_STRCO
AccessioniPrimary (citable) accession number: O86622
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.