O86478 (O86478_STRAG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase EMBL CAA75865.1
EC=4.2.2.1 EMBL CAA75865.1

Gene names

Name:

hylB EMBL CAA75865.1

Organism

Streptococcus agalactiae EMBL CAA75865.1

Taxonomic identifier

1311 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	1072 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

Ontologies

Keywords
Domain	Signal EMBL CAA75865.1
Molecular function	Lyase EMBL CAA75865.1
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 30	30	Potential EMBL CAA75865.1
	Chain	31 – 1072	1042	Potential EMBL CAA75865.1		PRO_5000147264

Sequences

	Sequence		Length	Mass (Da)
	O86478 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 3AF734A8DF40A08A	FASTA	1,072	121,165
	10 20 30 40 50 60 MEIKKKYRIM LYSALILGTI LVNNSYQAKA EELTKTTSTS QIRDTQTNNI EVLQTESTTV 70 80 90 100 110 120 KETSTTTTQQ DLSNPTASTA TATATHSTMK QVVDNQTQNK ELVKNGDFNQ TNPVSGSWSH 130 140 150 160 170 180 TSAREWSAWI DKENTADKSP IIQRTEQGQV SLSSDKGFRG AVTQKVNIDP TKKYEVKFDI 190 200 210 220 230 240 ETSNKAGQAF LRIMEKKDNN TRLWLSEMTS GTTNKHTLTK IYNPKLNVSE VTLELYYEKG 250 260 270 280 290 300 TGSATFDNIS MKAKGPKDSE HPQPVTTQIE ESVNTALNKN YVFNKADYQY TLTNPSLGKI 310 320 330 340 350 360 VGGILYPNAT GSTTVKISDK SGKIIKEVPL SVTASTEDKF TKLLDKWNDV TIGNHVYDTN 370 380 390 400 410 420 DSNMQKINQK LDETNAKNIK TIKLDSNHTF LWKDLDNLNN SAQLTATYRR LEDLAKQITN 430 440 450 460 470 480 PHSTIYKNEK AIRTVKESLA WLHQNFYNVN KDIEGSANWW DFEIGVPRSI TATLALMNNY 490 500 510 520 530 540 FTDAEIKTYT DPIEHFVPDA GYFRKTLDNP FKALGGNLVD MGRVKIIEGL LRKDNTIIEK 550 560 570 580 590 600 TSHSLKNLFT TATKAEGFYA DGSYIDHTNV AYTGAYGNVL IDGLTQLLPI IQETDYKISN 610 620 630 640 650 660 QELDMVYKWI NQSFLPLIVK GELMDMSRGR SISREAASSH AAAVEVLRGF LRLANMSNEE 670 680 690 700 710 720 RNLDLKSTIK TIITSNKFYN VFNNLKSYSD IANMNKMLND STVATKPLKS NLSTFNSMDR 730 740 750 760 770 780 LAYYNAEKDF GFALSLHSKR TLNYEGMNDE NTRGWYTGDG MFYLYNSDQS HYSNHFWPTV 790 800 810 820 830 840 NPYKMAGTTE KDAKREDTTK EFMSKHSKDA KEKTGQVTGT SDFVGSVKLN DHFALAAMDF 850 860 870 880 890 900 TNWDRTLTAQ KGWVILNDKI VFLGSNIKNT NGIGNVSTTI DQRKDDSKTP YTTYVNGKTI 910 920 930 940 950 960 DLKQASSQQF TDTKSVFLES KEPGRNIGYI FFKNSTIDIE RKEQTGTWNS INRTSKNTSI 970 980 990 1000 1010 1020 VSNPFITISQ KHDNKGDSYG YMMVPNIDRT SFDKLANSKE VELLENSSKQ QVIYDKNSQT 1030 1040 1050 1060 1070 WAVIKHDNQE SLINNQFKMN KAGLYLVQKV GNDYQNVYYQ PQTMTKTDQL AI

References

[1]	"The Streptococcus agalactiae hylB gene encoding hyaluronate lyase: completion of the sequence and expression analysis." Gase K., Ozegowski J., Malke H. Biochim. Biophys. Acta 1398:86-98(1998) [PubMed: 9602074] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Group B EMBL CAA75865.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y15903 Genomic DNA. Translation: CAA75865.1.
3D structure databases
HSSP	HSSP built from PDB template 1LXM based on UniProtKB Q53591.
ProteinModelPortal	O86478.
SMR	O86478. Positions 259-1072.
ModBase	Search...
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
BRENDA	4.2.2.1. 3065.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR008979. Galactose-bd-like. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR023295. Hyaluronate_lyase_beta_dom. IPR014756. Ig_E-set. IPR011071. Lyase_8-like_C. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.40.1380. Hyaluronate_lyase_beta_dom. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
Pfam	PF02278. Lyase_8. 1 hit. PF02884. Lyase_8_C. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF49785. Gal_bind_like. 1 hit. SSF74650. Gal_mut_like. 1 hit. SSF81296. Ig_E-set. 1 hit. SSF49863. Lyase_like_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O86478_STRAG

Accession

Primary (citable) accession number: O86478

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	March 8, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)