ID   O86136_9BURK            Unreviewed;       454 AA.
AC   O86136;
DT   01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1998, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   SubName: Full=Biphenyl dioxygenase alpha subunit {ECO:0000313|EMBL:CAA08985.1};
GN   Name=bphA1 {ECO:0000313|EMBL:CAA08985.1};
OS   Burkholderia sp. JB1.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=80621 {ECO:0000313|EMBL:CAA08985.1};
RN   [1] {ECO:0000313|EMBL:CAA08985.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=JB1 {ECO:0000313|EMBL:CAA08985.1};
RA   Dignum M., Parsons J.R., van Thor J.J., Hellingwerf K.J.;
RT   "Substrate specificity of the (chloro)biphenyl degradation pathway of
RT   Burkholderia strain JB1.";
RL   Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the bacterial ring-hydroxylating dioxygenase
CC       alpha subunit family. {ECO:0000256|ARBA:ARBA00008751}.
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DR   EMBL; AJ010057; CAA08985.1; -; Genomic_DNA.
DR   AlphaFoldDB; O86136; -.
DR   SMR; O86136; -.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd08881; RHO_alpha_C_NDO-like; 1.
DR   CDD; cd03472; Rieske_RO_Alpha_BPDO_like; 1.
DR   Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR   InterPro; IPR043266; RHO_NdoB-like_C.
DR   InterPro; IPR017941; Rieske_2Fe-2S.
DR   InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR   InterPro; IPR015881; Ring-hydroxy_dOase_2Fe2S_BS.
DR   InterPro; IPR015879; Ring_hydroxy_dOase_asu_C_dom.
DR   InterPro; IPR001663; Rng_hydr_dOase-A.
DR   PANTHER; PTHR43756:SF1; 3-PHENYLPROPIONATE_CINNAMIC ACID DIOXYGENASE SUBUNIT ALPHA; 1.
DR   PANTHER; PTHR43756; CHOLINE MONOOXYGENASE, CHLOROPLASTIC; 1.
DR   Pfam; PF00355; Rieske; 1.
DR   Pfam; PF00848; Ring_hydroxyl_A; 1.
DR   PRINTS; PR00090; RNGDIOXGNASE.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
DR   SUPFAM; SSF50022; ISP domain; 1.
DR   PROSITE; PS51296; RIESKE; 1.
DR   PROSITE; PS00570; RING_HYDROXYL_ALPHA; 1.
PE   3: Inferred from homology;
KW   2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW   Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797};
KW   Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000313|EMBL:CAA08985.1};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          58..174
FT                   /note="Rieske"
FT                   /evidence="ECO:0000259|PROSITE:PS51296"
SQ   SEQUENCE   454 AA;  51410 MW;  3D8F906E3AEF9DDF CRC64;
     MSSTMKDTQE APVRWSRNWT PDAIRALVDQ DNGKLDARIY ADQDLYQLEL ERVFGRSWLM
     LGHETHIPKI GDYLTTYMGE DPVIMVRQKD QSIKVFLNQC RHRGMRIVRS DGGNAKAFTC
     TYHGWAYDIA GNLVNVPFEK EAFCDKKEGD CGFDKADWGP LQARVETYKG LVFANWDPEA
     PDLKTYLSDA MPYMDVMLDR TEAGTEAIGG IQKWVIPCNW KFAAEQFCSD MYHAGTMSHL
     SGVLAGLPPE MDLTQIQLSK NGNQFRSAWG GHGAGWFIND SSILLSVMGP KITQYWTQGP
     AAEKAASVPQ LPILDMFGQH MTVFPTCSFL PGINTIRTWH PRGPNEVEVW AFVLVDADAP
     EDIKEEFRLQ NIRTFNAGVF EQDDGENWVE IQRVMRGHKA KSTFAVPKMG LNVPNKNNPA
     YPGKTAYVYA EEARGMYHHW SRMMSEPSWD TLKP
//