Reviewed, UniProtKB/Swiss-Prot O86130 (ARGR_BACLD)

Names and origin

Protein names

Recommended name:
    Arginine repressor

Gene names

Name:	argR
Synonyms:	ahrC
Ordered Locus Names:	BLi02596, BL01521

Organism

Bacillus licheniformis (strain DSM 13 / ATCC 14580) [Complete proteome] [HAMAP]

Taxonomic identifier

279010 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	149 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Regulates arginine biosynthesis genes and activates arginine deiminase pathway genes. HAMAP MF_00173
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis. [regulation] HAMAP MF_00173 Amino-acid degradation; L-arginine degradation via ADI pathway. HAMAP MF_00173
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the argR family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis Arginine metabolism Transcription Transcription regulation
Cellular component	Cytoplasm
Ligand	DNA-binding
Molecular function	Activator Repressor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: HAMAP transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transcription factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 149	149	Arginine repressor HAMAP MF_00173		PRO_0000205069

Sequences

	Sequence		Length	Mass (Da)
	O86130-1 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 86638F0E3EF9B1F2	FASTA	149	16,832
	10 20 30 40 50 60 MNKGQRHIKI REIITANEIE TQDELVDILK KDGYNVTQAT VSRDIKELHL VKVPTNNGSY 70 80 90 100 110 120 KYSLPADQRF NPLSKLKRSL MDAFVKIDSA SHLIVLKTMP GNAQAIGALM DNLDWEEIMG 130 140 TICGDDTILI ICRTHDDTKV VQKKILELL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The arcABDC gene cluster, encoding the arginine deiminase pathway of Bacillus licheniformis, and its activation by the arginine repressor argR." Maghnouj A., de Sousa Cabral T.F., Stalon V., Vander Wauven C. J. Bacteriol. 180:6468-6475(1998) [PubMed: 9851988] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential." Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G. J. Mol. Microbiol. Biotechnol. 7:204-211(2004) [PubMed: 15383718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species." Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A. , Galleron N., Ehrlich S.D., Berka R.M. Genome Biol. 5:RESEARCH077.1-RESEARCH077.12(2004) [PubMed: 15461803] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y17553 Genomic DNA. Translation: CAA76776.1. AE017333 Genomic DNA. Translation: AAU41470.1. CP000002 Genomic DNA. Translation: AAU24111.1.
RefSeq	YP_079749.1. YP_092163.1.
3D structure databases
HSSP	HSSP built from PDB template 1F9N based on UniProtKB P17893.
SMR	O86130. Positions 1-149.
ModBase	Search...
Protein-protein interaction databases
STRING	O86130.
Genome annotation databases
GeneID	3027539. 3100124.
GenomeReviews	Gene locus BLi02596 in contig AE017333_GR. Gene locus BL01521 in contig CP000002_GR.
KEGG	bld:BLi02596. bli:BL01521.
NMPDR	fig|279010.5.peg.439.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O86130.
OMA	IGALMDN.
Enzyme and pathway databases
BioCyc	BLIC279010:BL01521-MON.
Family and domain databases
HAMAP	MF_00173. [Tree]
InterPro	IPR001669. Arg_repress. IPR011991. Wing_hlx_DNA_bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.40. Arg_repress. 1 hit. G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF01316. Arg_repressor. 1 hit. PF02863. Arg_repressor_C. 1 hit. [Graphical view]
PRINTS	PR01467. ARGREPRESSOR.
ProDom	PD007402. Arg_repress. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01529. argR_whole. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGR_BACLD

Accession

Primary (citable) accession number: O86130
Secondary accession number(s): Q65HJ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1998
Last modified:	November 3, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)