O85739 (O85739_PSEAI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydroaeruginoic acid synthetase EMBL AAC83656.1

Gene names

Name:

pchE EMBL AAC83656.1

Organism

Pseudomonas aeruginosa EMBL AAC83656.1

Taxonomic identifier

287 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	1438 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Gene Ontology (GO)
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro ligase activity Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O85739 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 22194DF7BC07E234	FASTA	1,438	156,422
	10 20 30 40 50 60 MDLPPDSRTA LRDWLTEQLA DLLGEPLADV RALADDDDLL GCGLDSIRLM YLQERLRARG 70 80 90 100 110 120 STLDFAQLAQ RPCLGAWLDL LACADRLSAP ATVALPTAQD RDQPFELSSV QQAYWLGRGA 130 140 150 160 170 180 GEVLGNVSCH AFLEFRTRDV DPQRLAAAAE CVRQRHPMLR ARFLDGRQQI LPTPPLSCFD 190 200 210 220 230 240 LQDWRTLQVD EAERDWQALR DWRAHECLAV ERGQVFLLGL VRMPGGEDRL WLSLDLLAAD 250 260 270 280 290 300 VESLRLLLAE LGVAYLAPER LAEPPALHFA DYLAHRAAQR AEAAARARDY WLERLPRLPD 310 320 330 340 350 360 APALPLACAP ESIRQPRTRR LAFQLSAGES RRLERLAAQH GVTLSSVFGC AFALVLARWS 370 380 390 400 410 420 ESAEFLLNVP LFDRHADDPR IGEVIADFTT LLLLECRMQA GVSFAEAVKS FQRNLHGAID 430 440 450 460 470 480 HAAFPALEVL REARRQGQPR SAPVVFASNL GEEGFVPAAF RDAFGDLHDM LSQTPQVWLD 490 500 510 520 530 540 HQLYRVGDGI LLAWDSVVGL FPEGLPETMF EAYVGLLQRL CDSAWGQPAD LPLPWAQQAR 550 560 570 580 590 600 RALLNGQPAC ATARTLHRDF FLRAAEAPDA DALLYRDQRV TRGELAERAL RIAGGLREAG 610 620 630 640 650 660 VRPGDAVEVS LPRGPQQVAA VFGVLAAGAC YVPLDIDQPP ARRRLIEEAA GVCLAITEED 670 680 690 700 710 720 DPQALPPRLD VQRLLRGPAL AAPVPLAPQA SAYVIYTSGS TGVPKGVEVS HAAAINTIDA 730 740 750 760 770 780 LLDLLRVNAS DRLLAVSALD FDLSVFDLFG GLGAGASLVL PAQEQARDAA AWAEAIQRHA 790 800 810 820 830 840 VSLWNSAPAL LEMALSLPAS QADYRSLRAV LLSGDWVALD LPGRLRPRCA EGCRLHVLGG 850 860 870 880 890 900 ATEAGIWSNL QSVDTVPPHW RSIPYGRPLP GQAYRVVDTH GRDVPDLVVG ELWIGGASLA 910 920 930 940 950 960 RGYRNDPELS ARRFVHDAQG RWYRTGDRGR YWGDGTLEFL GRVDQQVKVR GQRIELGEVE 970 980 990 1000 1010 1020 AALCAQAGVE SACAAVLGGG VASLGAVLVP RLAPRAEGSM DLPAAQPFAG LAEAEAVLTR 1030 1040 1050 1060 1070 1080 EILGALLEAP LELDDGLRRR WLDWLADSAA SALPSLDEAL RRLGWQAAGL TAMGNALRGL 1090 1100 1110 1120 1130 1140 LAGEQAPAAL LLDPWLAPQA VAARLPDGRE ALARLLEALP TPAAGERLRV AVLDTRAGLW 1150 1160 1170 1180 1190 1200 LDQGMASLLR PGLELTLFER SRVLLDAAAT RLPERIVVQA LDDGLLPAEH LGRYDRVISF 1210 1220 1230 1240 1250 1260 AALHAYEASR EGLALAAALL RPQGRLLLVD LLCESPLALL GAALLDDRPL RLAELPSLLA 1270 1280 1290 1300 1310 1320 DLAAAGLAPR CLWRSERIAL VEALAPGLGL DAAALQAGLE QRLPQAMRPE RLWCLPSLPL 1330 1340 1350 1360 1370 1380 NGNGKVDRRR LAESMTRALG ECRHEPSAEE PLEAHEQALA ECWEAVLKRP VRRREASFFS 1390 1400 1410 1420 1430 LGGDSLLATR LLAGIRERFG VRLGMADFYR QPTLAGLARH LQVQTVEIEE TQLEEGVL

References

[1]	"Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa." Reimmann C., Serino L., Beyeler M., Haas D. Microbiology 144:3135-3148(1998) [PubMed: 9846750] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: PAO1 EMBL AAC83656.1.
[2]	"Essential PchG-dependent reduction in pyochelin biosynthesis of Pseudomonas aeruginosa." Reimmann C., Patel H.M., Serino L., Barone M., Walsh C.T., Haas D. J. Bacteriol. 183:813-820(2001) [PubMed: 11208777] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: PAO1 EMBL AAC83656.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF074705 Genomic DNA. Translation: AAC83656.1.
PIR	T17402.
RefSeq	NP_252916.1. NC_002516.2.
3D structure databases
HSSP	HSSP built from PDB template 1DNY based on UniProtKB O30409.
ProteinModelPortal	O85739.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	880048.
GenomeReviews	Gene locus PA4226 in contig AE004091_GR.
KEGG	pae:PA4226.
NMPDR	fig|208964.1.peg.4226.
PATRIC	19843142. VBIPseAer58763_4427.
Organism-specific databases
PseudoCAP	PA4226.
Phylogenomic databases
HOGENOM	HBG676528.
OMA	CAPESIR.
ProtClustDB	CLSK868537.
Enzyme and pathway databases
BioCyc	PAER208964:PA4226-MONOMER.
Family and domain databases
InterPro	IPR010071. AA_adenyl_domain. IPR009081. Acyl_carrier_prot-like. IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. IPR001242. Condensatn. IPR013624. NRPS. IPR006163. Phsphopanteth-bd. IPR006162. PPantetheine_attach_site. [Graphical view]
Gene3D	G3DSA:1.10.1200.10. ACP_like. 2 hits.
KO	K12239.
Pfam	PF00501. AMP-binding. 1 hit. PF00668. Condensation. 1 hit. PF08415. NRPS. 1 hit. PF00550. PP-binding. 2 hits. [Graphical view]
SUPFAM	SSF47336. ACP_like. 2 hits.
TIGRFAMs	TIGR01733. AA-adenyl-dom. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 2 hits. PS00455. AMP_BINDING. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O85739_PSEAI

Accession

Primary (citable) accession number: O85739
Secondary accession number(s): Q7DC78

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	December 14, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)