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O85290

- DAPD_BUCAP

UniProt

O85290 - DAPD_BUCAP

Protein

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Gene

dapD

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 2 (30 Aug 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei104 – 1041SubstrateUniRule annotation
    Binding sitei141 – 1411SubstrateUniRule annotation

    GO - Molecular functioni

    1. 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. diaminopimelate biosynthetic process Source: UniProtKB-HAMAP
    2. lysine biosynthetic process via diaminopimelate Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Diaminopimelate biosynthesis, Lysine biosynthesis

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-233-MONOMER.
    UniPathwayiUPA00034; UER00019.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferaseUniRule annotation (EC:2.3.1.117UniRule annotation)
    Alternative name(s):
    Tetrahydrodipicolinate N-succinyltransferaseUniRule annotation
    Short name:
    THDP succinyltransferaseUniRule annotation
    Short name:
    THP succinyltransferaseUniRule annotation
    Short name:
    Tetrahydropicolinate succinylaseUniRule annotation
    Gene namesi
    Name:dapDUniRule annotation
    Ordered Locus Names:BUsg_223
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2732732,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferasePRO_0000196924Add
    BLAST

    Interactioni

    Subunit structurei

    Homotrimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi198804.BUsg223.

    Structurei

    3D structure databases

    ProteinModelPortaliO85290.
    SMRiO85290. Positions 1-271.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the transferase hexapeptide repeat family.UniRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG2171.
    KOiK00674.
    OMAiYIARNTV.
    OrthoDBiEOG68H8BV.

    Family and domain databases

    Gene3Di1.10.166.10. 1 hit.
    HAMAPiMF_00811. DapD.
    InterProiIPR005664. DapD_Trfase_Hexpep_rpt_fam.
    IPR001451. Hexapep_transf.
    IPR023180. THP_succinylTrfase_dom1.
    IPR011004. Trimer_LpxA-like.
    [Graphical view]
    PANTHERiPTHR19136:SF52. PTHR19136:SF52. 1 hit.
    PfamiPF00132. Hexapep. 1 hit.
    PF14805. THDPS_N_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF51161. SSF51161. 1 hit.
    TIGRFAMsiTIGR00965. dapD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O85290-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKYYDIIEN AYLKKNEVNT KNIDIETKQT IHHVIELLNS GKIRVAEKKD    50
    NIWITNQWIK KSILLYMYLN QNNVFQGSFS NYYDKIPLKY ENYNEKKFKE 100
    ERIRVVPPAT IRYGSFINSN TIIMPSYVNI GAYVDQGTMI DTWTTVGSCA 150
    QIGKNVHLSG GVGIGGVLEP LQNNPTIIED NCFIGARSEI VEGVIIEEGS 200
    VISMGVFIGQ STKIYNRETG EILYGRVPAN SVVVSGSLPS KDRKYNLYAA 250
    VIVKRVDSKT LNKVEINQLL RDK 273
    Length:273
    Mass (Da):30,928
    Last modified:August 30, 2002 - v2
    Checksum:i58D7AEE35DE356C9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67782.1.
    AF060492 Genomic DNA. Translation: AAC32330.1.
    RefSeqiNP_660571.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM67782; AAM67782; BUsg_223.
    GeneIDi1005422.
    KEGGibas:BUsg223.
    PATRICi21247241. VBIBucAph100086_0234.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67782.1 .
    AF060492 Genomic DNA. Translation: AAC32330.1 .
    RefSeqi NP_660571.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali O85290.
    SMRi O85290. Positions 1-271.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg223.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM67782 ; AAM67782 ; BUsg_223 .
    GeneIDi 1005422.
    KEGGi bas:BUsg223.
    PATRICi 21247241. VBIBucAph100086_0234.

    Phylogenomic databases

    eggNOGi COG2171.
    KOi K00674.
    OMAi YIARNTV.
    OrthoDBi EOG68H8BV.

    Enzyme and pathway databases

    UniPathwayi UPA00034 ; UER00019 .
    BioCyci BAPH198804:GHMG-233-MONOMER.

    Family and domain databases

    Gene3Di 1.10.166.10. 1 hit.
    HAMAPi MF_00811. DapD.
    InterProi IPR005664. DapD_Trfase_Hexpep_rpt_fam.
    IPR001451. Hexapep_transf.
    IPR023180. THP_succinylTrfase_dom1.
    IPR011004. Trimer_LpxA-like.
    [Graphical view ]
    PANTHERi PTHR19136:SF52. PTHR19136:SF52. 1 hit.
    Pfami PF00132. Hexapep. 1 hit.
    PF14805. THDPS_N_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51161. SSF51161. 1 hit.
    TIGRFAMsi TIGR00965. dapD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.
    2. "Sequence analysis of a DNA fragment from Buchnera aphidicola (Aphid endosymbiont) containing the genes dapD-htrA-ilvI-ilvH-ftsL-ftsI-murE."
      Thao M.L., Baumann P.
      Curr. Microbiol. 37:214-216(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 103-273.

    Entry informationi

    Entry nameiDAPD_BUCAP
    AccessioniPrimary (citable) accession number: O85290
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: August 30, 2002
    Last modified: October 1, 2014
    This is version 94 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3