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O85142 (O85142_STAAU) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

CzrA protein EMBL BAA36687.1

HTH-type transcriptional repressor CzrA EMBL AHW65763.1

Repressor protein EMBL AAC32484.1
Gene names
Name:rzcA EMBL AAC32484.1
Synonyms:CzrA EMBL BAA36687.1, czrA EMBL AHW65763.1
ORF Names:CH52_08235 EMBL AHM70293.1, X998_2124 EMBL AHW65763.1
OrganismStaphylococcus aureus [Complete proteome] [HAMAP] EMBL AAC32484.1
Taxonomic identifier1280 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length106 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 HTH arsR-type DNA-binding domain. RuleBase RU000711

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding841Zinc PDB 1R1V PDB 2M30
Metal binding861Zinc; via pros nitrogen PDB 1R1V PDB 2M30
Metal binding971Zinc; via pros nitrogen PDB 1R1V PDB 2M30
Metal binding1001Zinc; via tele nitrogen PDB 1R1V PDB 2M30

Sequences

Sequence LengthMass (Da)Tools
O85142 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: D3EB24D10D5EA4BC

FASTA10611,989
        10         20         30         40         50         60 
MSEQYSEINT DTLERVTEIF KALGDYNRIR IMELLSVSEA SVGHISHQLN LSQSNVSHQL 

        70         80         90        100 
KLLKSVHLVK AKRQGQSMIY SLDDIHVATM LKQAIHHANH PKESGL 

« Hide

References

[1]"Molecular characterization of a chromosomal determinant conferring resistance to zinc and cobalt ions in Staphylococcus aureus."
Xiong A., Jayaswal R.K.
J. Bacteriol. 180:4024-4029(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: RN450 EMBL AAC32484.1.
[2]"Chromosome-determined zinc-responsible operon czr in Staphylococcus aureus strain 912."
Kuroda M., Hayashi H., Ohta T.
Microbiol. Immunol. 43:115-125(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 912 EMBL BAA36687.1.
[3]"A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins."
Eicken C., Pennella M.A., Chen X., Koshlap K.M., VanZile M.L., Sacchettini J.C., Giedroc D.P.
J. Mol. Biol. 333:683-695(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH ZINC.
[4]"Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state."
Arunkumar A.I., Campanello G.C., Giedroc D.P.
Proc. Natl. Acad. Sci. U.S.A. 106:18177-18182(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR.
[5]"Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods."
Chakravorty D.K., Wang B., Lee C.W., Guerra A.J., Giedroc D.P., Merz K.M.
J. Biomol. NMR 56:125-137(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR IN COMPLEX WITH ZINC.
[6]"Genome Sequence of Bacterial Interference Strain Staphylococcus aureus 502A."
Parker D., Narechania A., Sebra R., Deikus G., Larussa S., Ryan C., Smith H., Prince A., Mathema B., Ratner A.J., Kreiswirth B., Planet P.J.
Genome Announc. 2:e00284-14(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 502A EMBL AHM70293.1.
[7]"Genome sequence of Bacterial Interference Strain Staphylococcus aureus 502A."
Parker D., Narechania A., Sebra R., Planet P.J.
Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[8]"Genome sequence of Staphylococcus aureus NRS 100."
Sichtig H., Utter B., Tallon L.J., Deshong S.Lisa., Sengamalay N., Nagaraj S., McCracken C.L., Daugherty S.
Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NRS 100 EMBL AHW65763.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF044951 Genomic DNA. Translation: AAC32484.1.
CP007454 Genomic DNA. Translation: AHM70293.1.
CP007539 Genomic DNA. Translation: AHW65763.1.
AB016431 Genomic DNA. Translation: BAA36687.1.
PIRT44366.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1R1UX-ray2.00A/B/C/D1-106[»]
1R1VX-ray2.30A/B1-106[»]
2KJBNMR-A/B1-106[»]
2KJCNMR-A/B1-106[»]
2M30NMR-A/B1-106[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-49001N.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

CMRSearch...

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR001845. HTH_ArsR_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PRINTSPR00778. HTHARSR.
SMARTSM00418. HTH_ARSR. 1 hit.
[Graphical view]
PROSITEPS50987. HTH_ARSR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceO85142.

Entry information

Entry nameO85142_STAAU
AccessionPrimary (citable) accession number: O85142
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: June 11, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)