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O85142 (O85142_STAAU) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Repressor protein EMBL AAC32484.1
Gene names
Name:rzcA EMBL AAC32484.1
Synonyms:CzrA EMBL BAA36687.1
OrganismStaphylococcus aureus EMBL AAC32484.1
Taxonomic identifier1280 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length106 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 HTH arsR-type DNA-binding domain. RuleBase RU000711

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding841Zinc PDB 1R1V PDB 2M30
Metal binding861Zinc; via pros nitrogen PDB 1R1V PDB 2M30
Metal binding971Zinc; via pros nitrogen PDB 1R1V PDB 2M30
Metal binding1001Zinc; via tele nitrogen PDB 1R1V PDB 2M30

Sequences

Sequence LengthMass (Da)Tools
O85142 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: D3EB24D10D5EA4BC

FASTA10611,989
        10         20         30         40         50         60 
MSEQYSEINT DTLERVTEIF KALGDYNRIR IMELLSVSEA SVGHISHQLN LSQSNVSHQL 

        70         80         90        100 
KLLKSVHLVK AKRQGQSMIY SLDDIHVATM LKQAIHHANH PKESGL 

« Hide

References

[1]"Molecular characterization of a chromosomal determinant conferring resistance to zinc and cobalt ions in Staphylococcus aureus."
Xiong A., Jayaswal R.K.
J. Bacteriol. 180:4024-4029(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: RN450 EMBL AAC32484.1.
[2]"Chromosome-determined zinc-responsible operon czr in Staphylococcus aureus strain 912."
Kuroda M., Hayashi H., Ohta T.
Microbiol. Immunol. 43:115-125(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 912 EMBL BAA36687.1.
[3]"A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins."
Eicken C., Pennella M.A., Chen X., Koshlap K.M., VanZile M.L., Sacchettini J.C., Giedroc D.P.
J. Mol. Biol. 333:683-695(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEX WITH ZINC.
[4]"Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state."
Arunkumar A.I., Campanello G.C., Giedroc D.P.
Proc. Natl. Acad. Sci. U.S.A. 106:18177-18182(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR.
[5]"Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods."
Chakravorty D.K., Wang B., Lee C.W., Guerra A.J., Giedroc D.P., Merz K.M.
J. Biomol. NMR 56:125-137(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR IN COMPLEX WITH ZINC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF044951 Genomic DNA. Translation: AAC32484.1.
AB016431 Genomic DNA. Translation: BAA36687.1.
PIRT44366.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1R1UX-ray2.00A/B/C/D1-106[»]
1R1VX-ray2.30A/B1-106[»]
2KJBNMR-A/B1-106[»]
2KJCNMR-A/B1-106[»]
2M30NMR-A/B1-106[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-49001N.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR001845. HTH_ArsR_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PRINTSPR00778. HTHARSR.
SMARTSM00418. HTH_ARSR. 1 hit.
[Graphical view]
PROSITEPS50987. HTH_ARSR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceO85142.

Entry information

Entry nameO85142_STAAU
AccessionPrimary (citable) accession number: O85142
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: March 19, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)