Reviewed, UniProtKB/Swiss-Prot O84904 (GALT_LACCA)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase
      Short name=Gal-1-P uridylyltransferase
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:

galT

Organism

Lactobacillus casei

Taxonomic identifier

1582 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	486 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 486	486	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169906

Sequences

	Sequence		Length	Mass (Da)
	O84904-1 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 91A8EDE4F449B035	FASTA	486	54,162
	10 20 30 40 50 60 MTAISNHVGT IVKLNPDYTQ MDAVYLTNKL LNLIGDAALD LPGDADPLTN LDLMVKAAQE 70 80 90 100 110 120 NGKIPDSQAA RQILEAQLMD LATPTPSRIN QLFWDKYQAG PRVATDWFFA LSRANNYIQT 130 140 150 160 170 180 RAIAKNVVFP AKTEYGDLEI TINLSKPEKD PKDIAAAAHA AQSGYPACAL CLQTEGYAGR 190 200 210 220 230 240 TDFAARTNHR IIRFLLGGKT WGFQYSPYAY FNEHAIFLDA IHEPMVIDQS TFSNLLSIVS 250 260 270 280 290 300 MFPTYFVGSN ADLPIVGGSM LTHEHYQGGR HTFPMAKAPI ETQVEISGHP HVFAGIVKWP 310 320 330 340 350 360 MSVIRLVSAD SDELINAAEH VRQVWNQYTD ETVDVRAFVD GKPHHTVTPI ARRVGSEFQL 370 380 390 400 410 420 DLVLRDNQTS AEHPDGIFHP HQDVQHIKKE NIGLIEVMGR AILPARLKSE LAEVQKYLLG 430 440 450 460 470 480 EANTMKPMHK TWADQLKAKY DWTPENVEAQ MQAAVGRVFA RVLEDAGVFK RDEVGQKAFA RFCRAL

References

[1]	"The gal genes for the Leloir pathway of Lactobacillus casei 64H." Bettenbrock K., Alpert C.-A. Appl. Environ. Microbiol. 64:2013-2019(1998) [PubMed: 9603808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 64H.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF005933 Genomic DNA. Translation: AAC19330.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.7.7.12. 610.
Family and domain databases
HAMAP	MF_00571. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. galT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_LACCA

Accession

Primary (citable) accession number: O84904

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 26, 2002
Last sequence update:	November 1, 1998
Last modified:	June 16, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)