O84840 (IF3_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor IF-3

Gene names

Name:	infC
Ordered Locus Names:	CT_833

Organism

Chlamydia trachomatis (strain D/UW-3/Cx) [Reference proteome] [HAMAP]

Taxonomic identifier

272561 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Chlamydiae/Verrucomicrobia group › Chlamydiae › Chlamydiia › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia › Chlamydia trachomatis

Protein attributes

Sequence length	175 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins By similarity. HAMAP-Rule MF_00080
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the IF-3 family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 175	175	Translation initiation factor IF-3 HAMAP-Rule MF_00080		PRO_0000177506

Sequences

	Sequence		Length	Mass (Da)
	O84840 [UniParc]. Last modified May 30, 2000. Version 2. Checksum: F93AD7302F1DD084	FASTA	175	19,770
	10 20 30 40 50 60 MALNLRINRQ IRAPRVRVIG SAGEQLGILS IKEALDLAKE ANLDLVEVAS NSEPPVCKIM 70 80 90 100 110 120 DYGKYRYDVT KKEKDSKKAQ HQVRIKEVKL KPNIDDNDFL TKAKQARAFI EKGNKVKVSC 130 140 150 160 170 MFRGRELAYP EHGYKVIQRM CQGLEDIGFV ESEPKLNGRS LICVIAPGTL KTKKK

References

[1]

"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC68430.2.
PIR	A71465.
RefSeq	NP_220354.1. NC_000117.1.
3D structure databases
ProteinModelPortal	O84840.
SMR	O84840. Positions 4-78.
ModBase	Search...
Protein-protein interaction databases
STRING	272561.CT833.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC68430; AAC68430; CT_833.
GeneID	884636.
KEGG	ctr:CT833.
PATRIC	20381382. VBIChlTra43535_0920.
Phylogenomic databases
eggNOG	COG0290.
KO	K02520.
OMA	HDYQTKV.
ProtClustDB	PRK00028.
Family and domain databases
Gene3D	3.10.20.80. 1 hit.
HAMAP	MF_00080. IF-3.
InterPro	IPR019813. Translation_initiation_fac3_CS. IPR001288. Translation_initiation_fac_3. IPR019815. Translation_initiation_fac_3_C. IPR019814. Translation_initiation_fac_3_N. [Graphical view]
PANTHER	PTHR10938. PTHR10938. 1 hit.
Pfam	PF00707. IF3_C. 1 hit. PF05198. IF3_N. 1 hit. [Graphical view]
SUPFAM	SSF54364. IF3. 1 hit. SSF55200. IF3. 1 hit.
TIGRFAMs	TIGR00168. infC. 1 hit.
PROSITE	PS00938. IF3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IF3_CHLTR

Accession

Primary (citable) accession number: O84840

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 30, 2000
Last modified:	May 1, 2013
This is version 75 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program