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Protein

Translation initiation factor IF-3

Gene

infC

Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.UniRule annotation

GO - Molecular functioni

  1. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-3UniRule annotation
Gene namesi
Name:infCUniRule annotation
Ordered Locus Names:CT_833
OrganismiChlamydia trachomatis (strain D/UW-3/Cx)
Taxonomic identifieri272561 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000431: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 175175Translation initiation factor IF-3PRO_0000177506Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi272561.CT833.

Structurei

3D structure databases

ProteinModelPortaliO84840.
SMRiO84840. Positions 4-78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IF-3 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0290.
InParanoidiO84840.
KOiK02520.
OMAiGKFIYEQ.
OrthoDBiEOG63JRGJ.

Family and domain databases

Gene3Di3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPiMF_00080. IF_3.
InterProiIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERiPTHR10938. PTHR10938. 1 hit.
PfamiPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMiSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsiTIGR00168. infC. 1 hit.
PROSITEiPS00938. IF3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O84840-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALNLRINRQ IRAPRVRVIG SAGEQLGILS IKEALDLAKE ANLDLVEVAS
60 70 80 90 100
NSEPPVCKIM DYGKYRYDVT KKEKDSKKAQ HQVRIKEVKL KPNIDDNDFL
110 120 130 140 150
TKAKQARAFI EKGNKVKVSC MFRGRELAYP EHGYKVIQRM CQGLEDIGFV
160 170
ESEPKLNGRS LICVIAPGTL KTKKK
Length:175
Mass (Da):19,770
Last modified:May 30, 2000 - v2
Checksum:iF93AD7302F1DD084
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA. Translation: AAC68430.2.
PIRiA71465.
RefSeqiNP_220354.1. NC_000117.1.

Genome annotation databases

EnsemblBacteriaiAAC68430; AAC68430; CT_833.
GeneIDi884636.
KEGGictr:CT_833.
PATRICi20381382. VBIChlTra43535_0920.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA. Translation: AAC68430.2.
PIRiA71465.
RefSeqiNP_220354.1. NC_000117.1.

3D structure databases

ProteinModelPortaliO84840.
SMRiO84840. Positions 4-78.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272561.CT833.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC68430; AAC68430; CT_833.
GeneIDi884636.
KEGGictr:CT_833.
PATRICi20381382. VBIChlTra43535_0920.

Phylogenomic databases

eggNOGiCOG0290.
InParanoidiO84840.
KOiK02520.
OMAiGKFIYEQ.
OrthoDBiEOG63JRGJ.

Family and domain databases

Gene3Di3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPiMF_00080. IF_3.
InterProiIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERiPTHR10938. PTHR10938. 1 hit.
PfamiPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMiSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsiTIGR00168. infC. 1 hit.
PROSITEiPS00938. IF3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis."
    Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.
    Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: D/UW-3/Cx.

Entry informationi

Entry nameiIF3_CHLTR
AccessioniPrimary (citable) accession number: O84840
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: February 4, 2015
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.