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O84840 (IF3_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-3
Gene names
Name:infC
Ordered Locus Names:CT_833
OrganismChlamydia trachomatis (strain D/UW-3/Cx) [Reference proteome] [HAMAP]
Taxonomic identifier272561 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Protein attributes

Sequence length175 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins By similarity. HAMAP-Rule MF_00080

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00080

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00080.

Sequence similarities

Belongs to the IF-3 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 175175Translation initiation factor IF-3 HAMAP-Rule MF_00080
PRO_0000177506

Sequences

Sequence LengthMass (Da)Tools
O84840 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: F93AD7302F1DD084

FASTA17519,770
        10         20         30         40         50         60 
MALNLRINRQ IRAPRVRVIG SAGEQLGILS IKEALDLAKE ANLDLVEVAS NSEPPVCKIM 

        70         80         90        100        110        120 
DYGKYRYDVT KKEKDSKKAQ HQVRIKEVKL KPNIDDNDFL TKAKQARAFI EKGNKVKVSC 

       130        140        150        160        170 
MFRGRELAYP EHGYKVIQRM CQGLEDIGFV ESEPKLNGRS LICVIAPGTL KTKKK 

« Hide

References

[1]"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis."
Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.
Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: D/UW-3/Cx.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE001273 Genomic DNA. Translation: AAC68430.2.
PIRA71465.
RefSeqNP_220354.1. NC_000117.1.

3D structure databases

ProteinModelPortalO84840.
SMRO84840. Positions 4-78.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272561.CT833.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC68430; AAC68430; CT_833.
GeneID884636.
KEGGctr:CT_833.
PATRIC20381382. VBIChlTra43535_0920.

Phylogenomic databases

eggNOGCOG0290.
KOK02520.
OMAIKIDQHA.
OrthoDBEOG63JRGJ.
ProtClustDBPRK00028.

Family and domain databases

Gene3D3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPMF_00080. IF_3.
InterProIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERPTHR10938. PTHR10938. 1 hit.
PfamPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsTIGR00168. infC. 1 hit.
PROSITEPS00938. IF3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF3_CHLTR
AccessionPrimary (citable) accession number: O84840
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: April 16, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries