ID   NTPA_CHLTR              Reviewed;         209 AA.
AC   O84611;
DT   30-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   16-JUN-2009, entry version 44.
DE   RecName: Full=Nucleoside-triphosphatase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
DE            Short=NTPase;
GN   OrderedLocusNames=CT_606;
OS   Chlamydia trachomatis.
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydia.
OX   NCBI_TaxID=813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D/UW-3/Cx;
RX   MEDLINE=99000809; PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA   Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA   Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V.,
RA   Davis R.W.;
RT   "Genome sequence of an obligate intracellular pathogen of humans:
RT   Chlamydia trachomatis.";
RL   Science 282:754-759(1998).
CC   -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and
CC       dITP/ITP. Might exclude non-standard purines from DNA precursor
CC       pool, preventing thus incorporation into DNA and avoiding
CC       chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC   -!- COFACTOR: Divalent cations (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
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DR   EMBL; AE001273; AAC68209.1; -; Genomic_DNA.
DR   PIR; B71493; B71493.
DR   RefSeq; NP_220122.1; -.
DR   GeneID; 884386; -.
DR   GenomeReviews; AE001273_GR; CT_606.
DR   KEGG; ctr:CT606; -.
DR   HOGENOM; O84611; -.
DR   OMA; O84611; NACLKAS.
DR   BioCyc; CTRA315277:CT606-MON; -.
DR   BRENDA; 3.6.1.15; 108.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_01405; -; 1.
DR   InterPro; IPR002637; Ham1p-like.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    209       Nucleoside-triphosphatase.
FT                                /FTId=PRO_0000178152.
SQ   SEQUENCE   209 AA;  23315 MW;  63C1B9D2F02758F5 CRC64;
     MKILIASSHG YKVRETKVFL KKLGEFDIFS LVDYPSYHPP KETGETPEEN AIQKGLFAAQ
     TFRCWTIADD SMLIIPALGG LPGKLSASFA GEQANDKDHR KKLLENMRLL ENTIDRSAYF
     ECCVALISPF GKIFKAHASC EGTIAFEERG SSGFGYDPLF VKHDYKQTYA ELPEAIKNQV
     SHRAKALVKL QPYVETVLAN HLLAGKESL
//