O84545 (O84545_CHLTR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Putative tRNA (cytidine(34)-2'-O)-methyltransferase HAMAP MF_01885
EC=2.1.1.207 HAMAP MF_01885

Alternative name(s):
tRNA (cytidine/uridine-2'-O-)-methyltransferase HAMAP MF_01885

Gene names

Name:	yibK EMBL AAC68142.1
Ordered Locus Names:	CT_540

Organism

Chlamydia trachomatis

Taxonomic identifier

813 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	151 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Could methylate the ribose at the nucleotide 34 wobble position in tRNA By similarity. HAMAP MF_01885
Catalytic activity	S-adenosyl-L-methionine + 5-carboxymethylaminomethyluridine(34) in tRNA(Leu) = S-adenosyl-L-homocysteine + 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu). HAMAP MF_01885 S-adenosyl-L-methionine + cytidine(34) in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine(34) in tRNA. HAMAP MF_01885
Subcellular location	Cytoplasm By similarity HAMAP MF_01885.
Sequence similarities	Belongs to the RNA methyltransferase TrmH family. TrmL subfamily. HAMAP MF_01885

Ontologies

Keywords
Biological process	tRNA processing HAMAP MF_01885
Cellular component	Cytoplasm HAMAP MF_01885
Ligand	S-adenosyl-L-methionine HAMAP MF_01885
Molecular function	Methyltransferase HAMAP MF_01885 SAAS SAAS001537 EMBL AAC68142.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro S-adenosylmethionine-dependent methyltransferase activity Inferred from electronic annotation. Source: HAMAP tRNA methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Binding site	77	1	S-adenosyl-L-methionine; via carbonyl oxygen By similarity HAMAP MF_01885
	Binding site	99	1	S-adenosyl-L-methionine; via amide nitrogen By similarity HAMAP MF_01885
	Binding site	120	1	S-adenosyl-L-methionine; via amide nitrogen and carbonyl oxygen By similarity HAMAP MF_01885
	Binding site	128	1	S-adenosyl-L-methionine By similarity HAMAP MF_01885

Sequences

	Sequence		Length	Mass (Da)
	O84545 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 9AA2C054DEF22529	FASTA	151	16,757
	10 20 30 40 50 60 MRIVLHNPDI PQNTGNIGRT CVALGAELIL VRPLGFSLAD KFVKRAGMDY WERLSLSVVD 70 80 90 100 110 120 SLEEALLGVP KERIFCLTTK GSSYYGEREL PLDGTYIFGA ESKGLPQTVL DAYSSQCLYI 130 140 150 PMIEGTRSLN LATSVGIVMY EVARQNYKTL F

References

[1]	"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed: 9784136] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC68142.1.
PIR	C71503.
RefSeq	NP_220055.1. NC_000117.1.
3D structure databases
HSSP	HSSP built from PDB template 1MXI based on UniProtKB P44868.
ProteinModelPortal	O84545.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	884326.
GenomeReviews	Gene locus CT_540 in contig AE001273_GR.
KEGG	ctr:CT540.
PATRIC	20380677. VBIChlTra43535_0585.
Phylogenomic databases
HOGENOM	HBG309728.
OMA	EAWRQNG.
PhylomeDB	O84545.
ProtClustDB	CLSK871433.
Family and domain databases
HAMAP	MF_01885. tRNA_methyltr_TrmL. [Tree]
InterPro	IPR001537. SpoU_MeTrfase. IPR016914. tRNA_cyt/urid_MeTfrase. [Graphical view]
KO	K03216.
PANTHER	PTHR12029:SF26. PTHR12029:SF26. 1 hit.
Pfam	PF00588. SpoU_methylase. 1 hit. [Graphical view]
PIRSF	PIRSF029256. SpoU_TrmH_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O84545_CHLTR

Accession

Primary (citable) accession number: O84545

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)