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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:CT_454
OrganismiChlamydia trachomatis (strain D/UW-3/Cx)
Taxonomic identifieri272561 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000431 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515481 – 563Arginine--tRNA ligaseAdd BLAST563

Interactioni

Subunit structurei

Monomer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO84460.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
InParanoidiO84460.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

O84460-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTLLSFLTS LCSAAIHQAF PELEELTLDI TPSTKEHFGH YQCNDAMKLA
60 70 80 90 100
RVLHKSPRAI AESIVAHIPP TPFSSIEIAG AGFINFTFSK EFLASQLQTF
110 120 130 140 150
SKELANGFRA ASPQKVIIDF SSPNIAKDMH VGHLRSTIIG DCLARCFSFV
160 170 180 190 200
GHDVLRLNHI GDWGTAFGML ITYLQETSQE AIHQLEDLTA LYKKAHARFA
210 220 230 240 250
EDSEFKKRSQ HNVVALQSGD AQALALWKQI CSVSEKSFQT IYSILDVELH
260 270 280 290 300
TRGESFYNPF LAEVVADLES KNLVTLSDGA KCVFHEAFSI PLMIQKSDGG
310 320 330 340 350
YNYATTDVAA MRYRIQQDQA DRILIVTDSG QSLHFQLLEA TCLAAGYLPS
360 370 380 390 400
KGIFSHVGFG LVLDTQGRKF KTRSGENIKL RELLDTAVEK AKESLKAHRP
410 420 430 440 450
DISEEELAYQ GPILGINAIK YADLSSHRIN DYVFSFEKML RFEGNTAMSL
460 470 480 490 500
LYAYVRIQGI KRRMGLESPP QEGPLAVHEP AEEALALTLL RFPEILDLTL
510 520 530 540 550
RELCPHFLTD YLYALTNKFN AFFRDCHIEG SDSQQERLYL CGLTERTLST
560
GMHLLGLKTL NHL
Length:563
Mass (Da):62,980
Last modified:November 1, 1998 - v1
Checksum:i335C9A0CF6E00553
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA. Translation: AAC68054.1.
AF087268 Genomic DNA. Translation: AAD04046.1.
PIRiA71513.
RefSeqiNP_219967.1. NC_000117.1.
WP_009871812.1. NC_000117.1.

Genome annotation databases

EnsemblBacteriaiAAC68054; AAC68054; CT_454.
GeneIDi884196.
KEGGictr:CT_454.
PATRICifig|272561.5.peg.491.

Similar proteinsi

Entry informationi

Entry nameiSYR_CHLTR
AccessioniPrimary (citable) accession number: O84460
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: August 30, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families