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O84457

- CDSA_CHLTR

UniProt

O84457 - CDSA_CHLTR

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Protein

Phosphatidate cytidylyltransferase

Gene
cdsA, CT_451
Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:CT_451
OrganismiChlamydia trachomatis (strain D/UW-3/Cx)
Taxonomic identifieri272561 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000431: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei27 – 4721Helical; Reviewed predictionAdd
BLAST
Transmembranei67 – 8721Helical; Reviewed predictionAdd
BLAST
Transmembranei96 – 11621Helical; Reviewed predictionAdd
BLAST
Transmembranei124 – 14421Helical; Reviewed predictionAdd
BLAST
Transmembranei150 – 17021Helical; Reviewed predictionAdd
BLAST
Transmembranei202 – 22221Helical; Reviewed predictionAdd
BLAST
Transmembranei232 – 25221Helical; Reviewed predictionAdd
BLAST
Transmembranei277 – 29721Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 305305Phosphatidate cytidylyltransferasePRO_0000090733Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272561.CT451.

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575.
KOiK00981.
OMAiTLFSILY.
OrthoDBiEOG6TBHJT.

Family and domain databases

InterProiIPR000374. PC_trans.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O84457-1 [UniParc]FASTAAdd to Basket

« Hide

MFDSDHNSIF QSDLCQRLVV HSILLTFLVI LLCTSLYPSS AFIVGLLSSA    50
CAALGTYEMG AMVRIKFPFS FTRYSALGSA IFIALTCLTA RCKMCFPEHI 100
DLLPWFFLFF WTIRLVFKSR HYKLGPIGST GLALFCMLYV SVPIRLFLHI 150
LYGFVHTDTP FVGIWWAIFL IATTKSSDIF GYFFGKAFGK KRIAPVISPN 200
KTVVGFIAGC CGSILVSLLF YSHLPKAFAD QIAVPWILIA LGTVLGVSGF 250
FGDIIESTFK RDAQIKNSSD LESIGGMLDV LDSLLLSTPI VYAILLITQN 300
RTFLG 305
Length:305
Mass (Da):33,805
Last modified:November 1, 1998 - v1
Checksum:iBAC435DC5677FFCC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001273 Genomic DNA. Translation: AAC68051.1.
PIRiF71512.
RefSeqiNP_219964.1. NC_000117.1.

Genome annotation databases

EnsemblBacteriaiAAC68051; AAC68051; CT_451.
GeneIDi884225.
KEGGictr:CT_451.
PATRICi20380471. VBIChlTra43535_0488.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001273 Genomic DNA. Translation: AAC68051.1 .
PIRi F71512.
RefSeqi NP_219964.1. NC_000117.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272561.CT451.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC68051 ; AAC68051 ; CT_451 .
GeneIDi 884225.
KEGGi ctr:CT_451.
PATRICi 20380471. VBIChlTra43535_0488.

Phylogenomic databases

eggNOGi COG0575.
KOi K00981.
OMAi TLFSILY.
OrthoDBi EOG6TBHJT.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .

Family and domain databases

InterProi IPR000374. PC_trans.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis."
    Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.
    Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: D/UW-3/Cx.

Entry informationi

Entry nameiCDSA_CHLTR
AccessioniPrimary (citable) accession number: O84457
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: May 14, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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