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Protein

GTPase Obg

Gene

obg

Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi172MagnesiumUniRule annotation1
Metal bindingi192MagnesiumUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi165 – 172GTPUniRule annotation8
Nucleotide bindingi190 – 194GTPUniRule annotation5
Nucleotide bindingi215 – 218GTPUniRule annotation4
Nucleotide bindingi285 – 288GTPUniRule annotation4
Nucleotide bindingi315 – 317GTPUniRule annotation3

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandGTP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCTRA272561:G1G18-442-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase ObgUniRule annotation (EC:3.6.5.-UniRule annotation)
Alternative name(s):
GTP-binding protein ObgUniRule annotation
Gene namesi
Name:obgUniRule annotation
Ordered Locus Names:CT_418
OrganismiChlamydia trachomatis (strain D/UW-3/Cx)
Taxonomic identifieri272561 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000431 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003858151 – 335GTPase ObgAdd BLAST335

Proteomic databases

PRIDEiO84423

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO84423
SMRiO84423
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini159 – 334OBG-type GUniRule annotationAdd BLAST176

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9R Bacteria
COG0536 LUCA
InParanoidiO84423
KOiK03979
OMAiPHVGIVH

Family and domain databases

CDDicd01898 Obg, 1 hit
Gene3Di2.70.210.12, 1 hit
HAMAPiMF_01454 GTPase_Obg, 1 hit
InterProiView protein in InterPro
IPR031167 G_OBG
IPR035101 GTP-bd_Obg
IPR014100 GTP-bd_Obg/CgtA
IPR006169 GTP1_OBG_dom
IPR036726 GTP1_OBG_dom_sf
IPR006073 GTP_binding_domain
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
PfamiView protein in Pfam
PF01018 GTP1_OBG, 1 hit
PF01926 MMR_HSR1, 1 hit
PIRSFiPIRSF002401 GTP_bd_Obg/CgtA, 1 hit
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 1 hit
SSF82051 SSF82051, 1 hit
TIGRFAMsiTIGR02729 Obg_CgtA, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51710 G_OBG, 1 hit

Sequencei

Sequence statusi: Complete.

O84423-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFVDQITLEL RAGKGGNGVV AWRKEKYLPK GGPYGGNGGN GGSILIEAVT
60 70 80 90 100
NMYSFEEYRN LRFLKADDGQ AGASNNRTGR NGKDLVLKVP EGTLLRDAAT
110 120 130 140 150
GELIHDFTKD GERIVVCQGG RGGKGNVFFK TSTNRAPTKA TPGKPGEIRL
160 170 180 190 200
VELELKLIAD IGLVGFPNAG KSTLFNTLAR TEVKVGAYPF TTLHPSLGLV
210 220 230 240 250
HQEGMLYQKP WIMADIPGII EGASQNRGLG LDFLRHIERT RLLLFVIDIS
260 270 280 290 300
GIERHSPEQD LKILMGELLA YKEELKDKDM VIALNKIDQL LPDEREERVA
310 320 330
LLKQQFPDQE FILLSGLTGE GVDALYDLFK SKLSE
Length:335
Mass (Da):36,837
Last modified:November 1, 1998 - v1
Checksum:i171B7359C22F95D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA Translation: AAC68015.1
PIRiE71517
RefSeqiNP_219928.1, NC_000117.1
WP_009871770.1, NC_000117.1

Genome annotation databases

EnsemblBacteriaiAAC68015; AAC68015; CT_418
GeneIDi35556641
884698
KEGGictr:CT_418
PATRICifig|272561.5.peg.449

Similar proteinsi

Entry informationi

Entry nameiOBG_CHLTR
AccessioniPrimary (citable) accession number: O84423
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 13, 2009
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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