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Protein

Phosphocarrier protein HPr

Gene

ptsH

Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei36Pros-phosphohistidine intermediatePROSITE-ProRule annotation1

GO - Biological processi

Keywordsi

Biological processPhosphotransferase system, Sugar transport, Transport

Enzyme and pathway databases

BioCyciCTRA272561:G1G18-356-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphocarrier protein HPr
Alternative name(s):
Histidine-containing protein
Gene namesi
Name:ptsH
Ordered Locus Names:CT_337
OrganismiChlamydia trachomatis (strain D/UW-3/Cx)
Taxonomic identifieri272561 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000431 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001078491 – 109Phosphocarrier protein HPrAdd BLAST109

Structurei

3D structure databases

ProteinModelPortaliO84341
SMRiO84341
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 109HPrPROSITE-ProRule annotationAdd BLAST88

Sequence similaritiesi

Belongs to the HPr family.Curated

Phylogenomic databases

eggNOGiCOG1925 LUCA
InParanoidiO84341
KOiK11189
OMAiSEFYIEM

Family and domain databases

CDDicd00367 PTS-HPr_like, 1 hit
Gene3Di3.30.1340.10, 1 hit
InterProiView protein in InterPro
IPR000032 HPr-like
IPR035895 HPr-like_sf
IPR002114 PTS_HPr_Ser_P_site
PfamiView protein in Pfam
PF00381 PTS-HPr, 1 hit
PRINTSiPR00107 PHOSPHOCPHPR
SUPFAMiSSF55594 SSF55594, 1 hit
TIGRFAMsiTIGR01003 PTS_HPr_family, 1 hit
PROSITEiView protein in PROSITE
PS51350 PTS_HPR_DOM, 1 hit
PS00589 PTS_HPR_SER, 1 hit

Sequencei

Sequence statusi: Complete.

O84341-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGGNDSVLH RPVEAPLMED GELSAVFTIR NSSGIHVRPA GTIVKLFEGE
60 70 80 90 100
ECEATLTYLG KTVNARSVMS ILMLGASYNG EVAVHIKGPS ASRVMQKLSE

VFNSGFGEL
Length:109
Mass (Da):11,597
Last modified:November 1, 1998 - v1
Checksum:i031527B84906CDFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA Translation: AAC67932.1
PIRiD71528
RefSeqiNP_219844.1, NC_000117.1
WP_009871687.1, NC_000117.1

Genome annotation databases

EnsemblBacteriaiAAC67932; AAC67932; CT_337
GeneIDi35556554
884777
KEGGictr:CT_337
PATRICifig|272561.5.peg.363

Similar proteinsi

Entry informationi

Entry nameiPTHP_CHLTR
AccessioniPrimary (citable) accession number: O84341
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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