O84331 (TRPF_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	CT_327

Organism

Chlamydia trachomatis (strain D/UW-3/Cx) [Reference proteome] [HAMAP]

Taxonomic identifier

272561 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Chlamydiae/Verrucomicrobia group › Chlamydiae › Chlamydiia › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia › Chlamydia trachomatis

Protein attributes

Sequence length	208 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 208	208	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_0000154355

Sequences

	Sequence		Length	Mass (Da)
	O84331 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 586B86A93AEF705C	FASTA	208	22,739
	10 20 30 40 50 60 MKVKICGITH PDDAREAAKA GADYIGMIFA KDSRRCVSEE KAKYIVEAIQ EGNSEPVGVF 70 80 90 100 110 120 PEHSVEEILA ITETTGITSI QLSGEDILFK FSQLREHFSI FYVVSVYSNG QPSAALPPMN 130 140 150 160 170 180 DAVTVVYDHI GGERGSPFDW KAFSPFQHNN WMLGGGVNLW NIKEGISLLS PRGIDVSSGV 190 200 ECPGILRKDI FLMQALINSA KELSSSTL

References

[1]

"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC67920.1.
PIR	D71529.
RefSeq	NP_219834.1. NC_000117.1.
3D structure databases
ProteinModelPortal	O84331.
ModBase	Search...
Protein-protein interaction databases
STRING	272561.CT327.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC67920; AAC67920; CT_327.
GeneID	884791.
KEGG	ctr:CT327.
PATRIC	20380193. VBIChlTra43535_0352.
Phylogenomic databases
eggNOG	COG0135.
KO	K01817.
OMA	ISALHCE.
ProtClustDB	PRK01222.
Enzyme and pathway databases
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_CHLTR

Accession

Primary (citable) accession number: O84331

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1998
Last modified:	May 1, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program