O84322 (NUSG_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transcription antitermination protein nusG

Gene names

Name:	nusG
Ordered Locus Names:	CT_320

Organism

Chlamydia trachomatis

Taxonomic identifier

813 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	182 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase By similarity.
Sequence similarities	Belongs to the nusG family. Contains 1 KOW domain.

Ontologies

Keywords
Biological process	Transcription Transcription antitermination Transcription regulation Transcription termination
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	positive regulation of transcription elongation from RNA polymerase II promoter Inferred from electronic annotation. Source: InterPro transcription antitermination Inferred from electronic annotation. Source: UniProtKB-KW transcription termination, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 182	182	Transcription antitermination protein nusG		PRO_0000113924
Regions
	Domain	121 – 158	38	KOW

Sequences

	Sequence		Length	Mass (Da)
	O84322 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: E397E0456989B86A	FASTA	182	20,746
	10 20 30 40 50 60 MFKWYVVQVF TAQEKKVKKS LEDFKEASGM SDFIQQIILP SENVMEVKKG EHKIVEKYIW 70 80 90 100 110 120 PGYLLVKMHL TDESWSYVKK TQGVVEFLGG GAPVALSEEE VKNILADLEE KKSGVVQKHK 130 140 150 160 170 180 FEVGSQVKIN DGVFVNFVGV VSEVFHDKGR LSVMVSIFGR ETRVDDLEFW QVEEVVPGQE SE

References

[1]	"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed: 9784136] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC67913.1.
PIR	E71528.
RefSeq	NP_219825.1. NC_000117.1.
3D structure databases
ProteinModelPortal	O84322.
ModBase	Search...
2D gel databases
PHCI-2DPAGE	O84322.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	884799.
GenomeReviews	Gene locus CT_320 in contig AE001273_GR.
KEGG	ctr:CT320.
PATRIC	20380167. VBIChlTra43535_0342.
Phylogenomic databases
HOGENOM	HBG751162.
OMA	VASGCEK.
PhylomeDB	O84322.
ProtClustDB	PRK05609.
Family and domain databases
InterPro	IPR005824. KOW. IPR001062. Transcrpt_antiterm_NusG. IPR006645. Transcrpt_antiterm_NusG_N. IPR014722. Transl_SH3-like_sub. IPR008991. Translation_prot_SH3-like. [Graphical view]
Gene3D	G3DSA:2.30.30.30. Ribosomal_L2. 1 hit. G3DSA:3.30.70.940. Transcrpt_antiterm_NusG_N. 1 hit.
KO	K02601.
Pfam	PF02357. NusG. 1 hit. [Graphical view]
PRINTS	PR00338. NUSGTNSCPFCT.
SMART	SM00739. KOW. 1 hit. SM00738. NGN. 1 hit. [Graphical view]
SUPFAM	SSF82679. Transcrpt_antiterm_NusG_N. 1 hit. SSF50104. Transl_SH3_like. 1 hit.
TIGRFAMs	TIGR00922. NusG. 1 hit.
PROSITE	PS01014. NUSG. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NUSG_CHLTR

Accession

Primary (citable) accession number: O84322

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 26, 2001
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program