O84320 (RL1_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L1

Gene names

Name:	rplA
Synonyms:	rl1
Ordered Locus Names:	CT_318

Organism

Chlamydia trachomatis

Taxonomic identifier

813 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. HAMAP MF_01318_B Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity. HAMAP MF_01318_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	50S ribosomal protein L1 HAMAP MF_01318_B		PRO_0000125642

Sequences

	Sequence		Length	Mass (Da)
	O84320 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: BFB438DB498DDDFE	FASTA	232	24,728
	10 20 30 40 50 60 MTKHGKRIRG IQETYDLAKS YSLGEAIDIL KQCPTVRFDQ TVDVSVKLGI DPRKSDQQIR 70 80 90 100 110 120 GSVSLPHGTG KVLRILVFAA GDKAAEAIEA GADFVGSDDL VEKIKGGWVD FDVAVATPDM 130 140 150 160 170 180 MREVGKLGKV LGPRNLMPTP KAGTVTTDVV KTVAELRKGK IEFKADRAGV CNVGVAKLSF 190 200 210 220 230 DSAQIKENVE ALCAALVKAK PATAKGQYLV NFTISSTMGP GVTVDTRELI AL

References

[1]	"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed: 9784136] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC67911.1.
PIR	C71530.
RefSeq	NP_219823.1. NC_000117.1.
3D structure databases
ProteinModelPortal	O84320.
SMR	O84320. Positions 6-226.
ModBase	Search...
2D gel databases
PHCI-2DPAGE	O84320.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	884805.
GenomeReviews	Gene locus CT_318 in contig AE001273_GR.
KEGG	ctr:CT318.
PATRIC	20380163. VBIChlTra43535_0340.
Phylogenomic databases
HOGENOM	HBG297400.
OMA	KAGTVTM.
PhylomeDB	O84320.
ProtClustDB	PRK05424.
Family and domain databases
HAMAP	MF_01318_B. Ribosomal_L1_B. [Tree]
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. IPR016095. Ribosomal_L1_3-a/b-sand. IPR023673. Ribosomal_L1_CS. IPR023674. Ribosomal_L1_SF. [Graphical view]
Gene3D	G3DSA:3.30.190.20. Ribosomal_L1_2-a/b-sand. 2 hits. G3DSA:3.40.50.790. Ribosomal_L1_3-a/b-sand. 1 hit.
KO	K02863.
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAM	SSF56808. Ribosomal_L1. 1 hit.
TIGRFAMs	TIGR01169. RplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL1_CHLTR

Accession

Primary (citable) accession number: O84320

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program