O84307 (VATI_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type ATP synthase subunit I

Alternative name(s):
V-ATPase subunit I

Gene names

Name:	atpI
Ordered Locus Names:	CT_305

Organism

Chlamydia trachomatis

Taxonomic identifier

813 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	649 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the V-ATPase 116 kDa subunit family.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting two-sector ATPase complex, proton-transporting domain Inferred from electronic annotation. Source: InterPro
Molecular function	hydrogen ion transmembrane transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 649	649	V-type ATP synthase subunit I		PRO_0000119240
Regions
	Transmembrane	312 – 332	21	Helical; Potential
	Transmembrane	360 – 380	21	Helical; Potential
	Transmembrane	453 – 473	21	Helical; Potential
	Transmembrane	485 – 505	21	Helical; Potential
	Transmembrane	520 – 540	21	Helical; Potential
	Transmembrane	556 – 576	21	Helical; Potential
	Transmembrane	593 – 613	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	O84307 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 1D3FC48CF49850FB	FASTA	649	73,214
	10 20 30 40 50 60 MRVDVDKYLF IGREKSEFFS ACREIGAVEF LSKSKLKDSE KVRKLSEGLK VLNLLTKSCS 70 80 90 100 110 120 PADLVSTKSG YLVTEQLLQE IFDLNQEITT LTESLKALGK EIVRVKPLGD FSSEEIRELT 130 140 150 160 170 180 LKTGLAVRFL YKRHIEGAPL EVEEENVFYL ATAYNYDYYA VIGIVSLSKD IFTEIEAPRS 190 200 210 220 230 240 VNELREEEGH LQALLRKKKA RVCELYAYRE DLLEALCEQC NEQSLQHAEV SAEDLFDDKV 250 260 270 280 290 300 FSALGWVIVD RLDEVKKLCD SLGIYLERVQ PDPDEVIPTY LENHGLGALG ESLVNIYDTP 310 320 330 340 350 360 ASTDKDPSLW VFFSFFVFFS MIINDAGYGL VFLATSLFLS FKARKQIKRS IALKRFLQMF 370 380 390 400 410 420 MILGLGCVCW GGATTSFFGV SVSYTSPFRE YSLTHFLALK KAEYYLKERP KGYKELVHDY 430 440 450 460 470 480 PILKEKKTPK EFLLAQSTSS GDSVYKAVVY DKFIDNILME IALLVGVVHL SLGMLRYCRQ 490 500 510 520 530 540 RYSSIGWVIF MCGAYMYLPI YLQAVSLIHY ALHIPYELGG LVGYYVAFIG LGVAILGGVI 550 560 570 580 590 600 QRGLRGLDEI TAVIQVFSDV LSYLRLYALS LAGAMVGNTV MVMSERFSPA VGILIIIFGH 610 620 630 640 TVNIALSIMG GVIHGLRLNF IEWYHYSFDG GGKLLHPLKK VICQKSQNL

References

[1]

"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed: 9784136] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC67898.1.
PIR	G71530.
RefSeq	NP_219810.1. NC_000117.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	884819.
GenomeReviews	Gene locus CT_305 in contig AE001273_GR.
KEGG	ctr:CT305.
PATRIC	20380135. VBIChlTra43535_0326.
Phylogenomic databases
HOGENOM	HBG414031.
OMA	YIRLFAV.
ProtClustDB	PRK05771.
Family and domain databases
InterPro	IPR002490. ATPase_V0/A0-cplx_116kDa_su. [Graphical view]
KO	K02123.
PANTHER	PTHR11629. ATPase_V0/A0_116. 1 hit.
Pfam	PF01496. V_ATPase_I. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VATI_CHLTR

Accession

Primary (citable) accession number: O84307

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program