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Protein

Probable ATP-dependent Clp protease ATP-binding subunit

Gene

clpC

Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi234 – 2418ATPSequence analysis
Nucleotide bindingi571 – 5788ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ATP-dependent Clp protease ATP-binding subunit
Gene namesi
Name:clpC
Ordered Locus Names:CT_286
OrganismiChlamydia trachomatis (strain D/UW-3/Cx)
Taxonomic identifieri272561 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000431 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 854854Probable ATP-dependent Clp protease ATP-binding subunitPRO_0000191232Add
BLAST

Proteomic databases

PRIDEiO84288.

Interactioni

Protein-protein interaction databases

STRINGi272561.CT286.

Structurei

3D structure databases

ProteinModelPortaliO84288.
SMRiO84288. Positions 186-378.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini443 – 47836UVRPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ClpA/ClpB family. ClpC subfamily.Curated
Contains 1 UVR domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105C2Z. Bacteria.
COG0542. LUCA.
InParanoidiO84288.
KOiK03696.
OMAiIMVEPTS.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
3.40.50.300. 3 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR001270. ClpA/B.
IPR027417. P-loop_NTPase.
IPR001943. UVR_dom.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 2 hits.
PF10431. ClpB_D2-small. 1 hit.
PF02151. UVR. 1 hit.
[Graphical view]
PRINTSiPR00300. CLPPROTEASEA.
SMARTiSM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF81923. SSF81923. 1 hit.
PROSITEiPS50151. UVR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O84288-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFEKFTNRAK QVIKLAKKEA QRLNHNYLGT EHILLGLLKL GQGVAVNVLR
60 70 80 90 100
TLGVDFDTAK HEVERLIGYG PEIQVCGDPA LTGRVKKSFE SANEEAALLE
110 120 130 140 150
HNYVGTEHLL LGILNQSDGV ALQVLENLHV DPKEIRKEIL KELETFNLQL
160 170 180 190 200
PPSSSITPRN TNSSSSSKSS SPLGGHTLGG DKPEKLSALK AYGYDLTEMF
210 220 230 240 250
KESRLDPVIG RSAEVERLIL ILCRRRKNNP VLVGEAGVGK TAIVEGLAQK
260 270 280 290 300
IVSGEVPEAL RKKRLITLDL ALMIAGTKYR GQFEERIKAV MDEVRKHGNI
310 320 330 340 350
LLFIDELHTI VGAGAAEGAI DASHILKPAL ARGEIQCIGA TTLDEYRKHI
360 370 380 390 400
EKDAALERRF QKIVVQPPSV DETVEILRGL KKKYEEHHNV FITDEALVAA
410 420 430 440 450
AKLSDQYVHG RFLPDKAIDL LDEAGARVRV NTMGQPSDLV RLEAEIEKTK
460 470 480 490 500
QAKEQAIGTQ EYEKAASLRD EEKKLREKLG NMKQQWESNK EEHQVPVDEE
510 520 530 540 550
AVAQVVSVQT GIPAARLTEA ESEKLLTLET TLQKKVIGQS QAVASICRAI
560 570 580 590 600
RRSRTGIKDP NRPMGSFLFL GPTGVGKTLL AQQIAIEMFG GEDSLIQVDM
610 620 630 640 650
SEYMEKFAAT KMMGSPPGYV GHEEGGHLTE QVRRRPYCVV LFDEIEKAHP
660 670 680 690 700
DIMDLMLQIL EQGRLTDSFG RKIDFRNTII IMTSNLGADL IRKSGEIGFG
710 720 730 740 750
LRSHMDYAVI KEKIDAAVKK HLKPEFINRL DESVIFKPLE KEALSEIIHL
760 770 780 790 800
EINKLGSRLQ NYQMDLNIPD SVISFLVTKG HSPEMGARPL RRVVEQYLED
810 820 830 840 850
PLAEMLLKES CRQEARKLRA RLTEERVVFE REEEAVSALA IEGDGSEPIT

ADES
Length:854
Mass (Da):95,146
Last modified:November 1, 1998 - v1
Checksum:i7AD3FA9914B1D189
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA. Translation: AAC67879.1.
PIRiC71533.
RefSeqiNP_219791.1. NC_000117.1.
WP_010725148.1. NC_000117.1.

Genome annotation databases

EnsemblBacteriaiAAC67879; AAC67879; CT_286.
GeneIDi884839.
KEGGictr:CT_286.
PATRICi20380095. VBIChlTra43535_0306.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA. Translation: AAC67879.1.
PIRiC71533.
RefSeqiNP_219791.1. NC_000117.1.
WP_010725148.1. NC_000117.1.

3D structure databases

ProteinModelPortaliO84288.
SMRiO84288. Positions 186-378.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272561.CT286.

Proteomic databases

PRIDEiO84288.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC67879; AAC67879; CT_286.
GeneIDi884839.
KEGGictr:CT_286.
PATRICi20380095. VBIChlTra43535_0306.

Phylogenomic databases

eggNOGiENOG4105C2Z. Bacteria.
COG0542. LUCA.
InParanoidiO84288.
KOiK03696.
OMAiIMVEPTS.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
3.40.50.300. 3 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR001270. ClpA/B.
IPR027417. P-loop_NTPase.
IPR001943. UVR_dom.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 2 hits.
PF10431. ClpB_D2-small. 1 hit.
PF02151. UVR. 1 hit.
[Graphical view]
PRINTSiPR00300. CLPPROTEASEA.
SMARTiSM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF81923. SSF81923. 1 hit.
PROSITEiPS50151. UVR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCLPC_CHLTR
AccessioniPrimary (citable) accession number: O84288
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.