Reviewed, UniProtKB/Swiss-Prot O84250 (PHSG_CHLTR)

Names and origin

Protein names

Recommended name:
    Glycogen phosphorylase
    EC=2.4.1.1

Gene names

Name:	glgP
Ordered Locus Names:	CT_248

Organism

Chlamydia trachomatis [Complete proteome] [HAMAP]

Taxonomic identifier

813 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia

Protein attributes

Sequence length	814 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity.
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the glycogen phosphorylase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glycogen metabolism
Ligand	Pyridoxal phosphate
Molecular function	Glycosyltransferase Transferase
Technical term	Allosteric enzyme Complete proteome
Gene Ontology (GO)
Biological process	glycogen metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 814	814	Glycogen phosphorylase		PRO_0000188552
Amino acid modifications
	Modified residue	662	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	O84250-1 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 54DB793A7DFE4E5A	FASTA	814	92,725
	10 20 30 40 50 60 MYFDRTKINV ESMKQAILER VYCGVVQTPQ SASTRDIFTA VAKTVLEWMA KGWLKTQSSY 70 80 90 100 110 120 YDNDVKRVYY ISMEFLLGRS LKSNLLNLGL LDLVKEALFD LGYDFDQLVE MEHDAGLGNG 130 140 150 160 170 180 GLGRLAACFL DSMATLEIPA YGYGLRYDYG IFDQKIENGF QVESPDEWLR YGNPWEICRG 190 200 210 220 230 240 EYLYPVHFYG KVKHSIDSRG RDVAELVDSQ EVLAMAYDVP VPGFNNDAVN SLRLWQAQSR 250 260 270 280 290 300 HGFEFSYFNH GNYIRAIEDI ALAGNITRVL YPNDSISEGQ ELRLKQEYFL VSATIQDILR 310 320 330 340 350 360 RYTKTHLSLD KLSEKVSVQL NDTHPALGIA EMMRLLVDRE ELDWDVAWDA TTKIFNYTNH 370 380 390 400 410 420 TILPEALERW SLDLFSKVLP RHLEIIYEIN ARWLAKVSQK YPGDNDKRRA LSIIEEGSSK 430 440 450 460 470 480 FVNMANLAVV GTNKVNGVST FHSQLIKSTL FKDFVEFFPD KFINVTNGIT PRRWLALSNK 490 500 510 520 530 540 KLSSLLNRTI GTEYLTNLTH LHKVIPLAED SGFREEWRNI KIQNKEELAA RIYKELGVTV 550 560 570 580 590 600 NPQSIFDCHI KRIHEYKRQL MNILRVIYFY NEIRNGSGEI VPTTVIFGGK AAPGYAMAKL 610 620 630 640 650 660 IIKLINNVAA VVNNDPKVND QLKVIFWPNY RVSLAEAIIP ATDLSEQIST AGMEASGTGN 670 680 690 700 710 720 MKFALNGALT IGTMDGANIE MAEHIGKEHM FIFGLLEEEI SELRKEYYPQ GICNANPTIQ 730 740 750 760 770 780 EILDMIAQAK FSQEDKDLFK PIVNRLLNEG DPFFVLADLE AYINTQNRVA SLFKQPEEWT 790 800 810 KKSIYNVGGI GFFSSDRSIA EYASNIWNVS RPTS

References

[1]

"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed: 9784136] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE001273 Genomic DNA. Translation: AAC67841.1.
PIR	A71540.
RefSeq	NP_219753.1.
3D structure databases
HSSP	HSSP built from PDB template 2GPN based on UniProtKB P00489.
ModBase	Search...
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Genome annotation databases
GeneID	884873.
GenomeReviews	Gene locus CT_248 in contig AE001273_GR.
KEGG	ctr:CT248.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O84250.
OMA	RFNAGDH.
Enzyme and pathway databases
BioCyc	CTRA315277:CT248-MON.
BRENDA	2.4.1.1. 108.
Family and domain databases
InterPro	IPR011833. Glycg_phsphrylas. IPR000811. Glyco_trans_35. [Graphical view]
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02093. P_ylase. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHSG_CHLTR

Accession

Primary (citable) accession number: O84250

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1998
Last modified:	November 3, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)