O84217 (ALF1_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable fructose-bisphosphate aldolase class 1
EC=4.1.2.13

Alternative name(s):
Probable fructose-bisphosphate aldolase class I
Short name=FBP aldolase

Gene names

Name:	fbaB
Ordered Locus Names:	CT_215

Organism

Chlamydia trachomatis (strain D/UW-3/Cx) [Reference proteome] [HAMAP]

Taxonomic identifier

272561 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Chlamydiae/Verrucomicrobia group › Chlamydiae › Chlamydiia › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia › Chlamydia trachomatis

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. FbaB subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 348	348	Probable fructose-bisphosphate aldolase class 1		PRO_0000138943
Sites
	Active site	236	1	Schiff-base intermediate with dihydroxyacetone-P By similarity

Sequences

	Sequence		Length	Mass (Da)
	O84217 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: D68CA2CDB498A752	FASTA	348	37,988
	10 20 30 40 50 60 MTTIFDLLGK DADYLLNHKC VIKKEALTLP SGDLVSRVFA ESDRNNRVLR SLQQMFSCGR 70 80 90 100 110 120 LGGTGYLSIL PVDQGVEHTA GASFAKNPMY FDPENIVRLA MEAGCSAVAS SYGVLSILAR 130 140 150 160 170 180 RYAHKIPFLL KLNHNELLSY PTTYHQIFFS QVEDAYNMGA VAVGATIYFG SESSSEEIVA 190 200 210 220 230 240 VAEAFARARE LGLATVLWCY LRNPHFVVNN VDYHTAADLT GQADHLGATL GADIVKQKLP 250 260 270 280 290 300 TLQGGFKTIN FSKTDDLVYS ELSSNHPIDL CRYQVLNSYC GKVGLINSGG PSGQDDFAEA 310 320 330 340 VKTAVINKRA GGMGLILGRK AFQRPFSEGV RLLNLIQDIY LDPTISIS

References

[1]

"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC67807.1.
PIR	F71542.
RefSeq	NP_219719.1. NC_000117.1.
3D structure databases
ProteinModelPortal	O84217.
ModBase	Search...
Protein-protein interaction databases
STRING	272561.CT215.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC67807; AAC67807; CT_215.
GeneID	884913.
KEGG	ctr:CT215.
PATRIC	20379939. VBIChlTra43535_0230.
Phylogenomic databases
eggNOG	COG1830.
KO	K11645.
OMA	RYQVLNC.
ProtClustDB	PRK09250.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
InterPro	IPR013785. Aldolase_TIM. IPR002915. DeoC/FbaB/lacD_aldolase. [Graphical view]
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALF1_CHLTR

Accession

Primary (citable) accession number: O84217

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1998
Last modified:	May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program