O84189 (6PGL_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
6-phosphogluconolactonase
Short name=6PGL
EC=3.1.1.31

Gene names

Name:	pgl
Synonyms:	devB
Ordered Locus Names:	CT_186

Organism

Chlamydia trachomatis

Taxonomic identifier

813 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	256 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.
Sequence similarities	Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 256	256	6-phosphogluconolactonase		PRO_0000090093

Sequences

	Sequence		Length	Mass (Da)
	O84189 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: CA1D6B5668101BF0	FASTA	256	29,014
	10 20 30 40 50 60 MATLISLNDA NRMLIADSQE EFLQIACYDW ISTANKAIHK RGAFYVALSG GKTPLQIFQE 70 80 90 100 110 120 IVKKRAAISD CSKIVVFWGD ERANEDVEAG SNYLKAMDIL KGLRIPEDQI FRMDTADPKG 130 140 150 160 170 180 DEAYEALIQK YVPDAIFDMV MLGVGEDGHT LSLFPETHAL EEKERFVVFN EVPQLHTRRM 190 200 210 220 230 240 TLTFPIVRQA RHLVAYVQGE NKQDLFHKLV HPLGRDTFPI ERVGTPLNPV QWVLSSDSCR 250 KTDLADIPAD CKLEMF

References

[1]

"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed: 9784136] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC67778.1.
PIR	C71546.
RefSeq	NP_219690.1. NC_000117.1.
3D structure databases
ProteinModelPortal	O84189.
ModBase	Search...
2D gel databases
PHCI-2DPAGE	O84189.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	884943.
GenomeReviews	Gene locus CT_186 in contig AE001273_GR.
KEGG	ctr:CT186.
PATRIC	20379875. VBIChlTra43535_0200.
Phylogenomic databases
HOGENOM	HBG725991.
OMA	APFNSEI.
PhylomeDB	O84189.
ProtClustDB	CLSK871240.
Family and domain databases
InterPro	IPR005900. 6-phosphogluconolactonase_DevB. IPR006148. Glc/Gal-6P_isomerase. [Graphical view]
KO	K01057.
Pfam	PF01182. Glucosamine_iso. 1 hit. [Graphical view]
TIGRFAMs	TIGR01198. Pgl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_CHLTR

Accession

Primary (citable) accession number: O84189

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program